Results 131 to 140 of about 387,641 (271)

GENERAL AND THEORETICAL: For a Science of Social Man: Convergences in Anthropology, Psychology, and Sociology. Howard Becker, John Gillin, A. Irving Hallowell, George Peter Murdock, Theodore M. Newcomb, Talcott Parsons, and M. Brewster Smith [PDF]

American Anthropologist, 1955
openaire   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

H Indez of the spanish journals of Social Sciences and Law according to Google Scholar (2002-2011) [PDF]

, 2013
Se presentan rankings por disciplinas de las revistas científicas españolas de Ciencias Sociales y Jurídicas según Google Scholar (GS) para el periodo 2002-2011. Se ordenan de acuerdo con el índice h que es el indicador bibliométrico adoptado por Google.
Delgado López-Cózar, Emilio, Ruiz-Pérez, Rafael, Jiménez Contreras, Evaristo, Marcos Cartagena, Diego   +3 more
core  

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Assessing Students’ Knowledge and Attitudes Regarding the Risks and Prevention of Consanguineous Marriage: A Cross-Sectional Online Survey

Journal of Multidisciplinary Healthcare
Ammar Abdulrahman Jairoun,1,2 Sabaa Saleh Al-Hemyari,2,3 Moyad Shahwan,4,5 Hidayah Karuniawati,6,7 Samer H Zyoud,4,8– 10 Eman Abu-Gharbieh,11 Sa’ed H Zyoud,12,13 Mena Al-Ani,14 Mustafa Habeb,15 Maimona Jairoun5 1Health and Safety Department, Dubai ...
Jairoun AA, Al-Hemyari SS, Shahwan M, Karuniawati H, Zyoud SH, Abu-Gharbieh E, Zyoud SH, Al-Ani M, Habeb M, Jairoun M   +9 more
doaj  

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Retirement villages: An alternative form of housing on an ageing landscape

, 2006
Retirement villages are a relatively new form of housing to appear on the ageing landscape. The demand for this style of living by a small, but increasing, proportion of the older population suggests these places provide a viable alternative lifestyle to
Grant, Bevan C.
core  

Constructing an understanding of mind : the development of children's social understanding within social interaction [PDF]

, 2004
Theories of children's developing understanding of mind tend to emphasize either individualistic processes of theory formation, maturation, or introspection, or the process of enculturation.
Lewis, Charlie, Carpendale, Jeremy I.
core