Results 111 to 120 of about 387,641 (271)

Embodiment in social psychology

, 2012
Psychologists are increasingly interested in embodiment based on the assumption that thoughts, feelings, and behaviors are grounded in bodily interaction with the environment.
Simone Schnall, Schwarz, Norbert, Schnall, Simone S., John A. Bargh, Meier, Brian P., Brian P. Meier, Norbert Schwarz, Schnall, Simone, Bargh, John A.   +8 more
core   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Young people and illicit drug use: A health promotion model to differentiate abstinence or recreational drug use from misuse

, 2004
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University, 27/04/2004.The thesis is a study of illicit drug use and attitudes to drugs education amongst young people from different socio-economic backgrounds.
Allen, Deborah
core  

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Mathemetics and Statistics Skills in the Social Sciences

, 2010
The issues concerning numeracy and quantitative skills that exist for social scientists are somewhat different from those affecting many within the natural sciences and technology-related disciplines.
Gibbs, Graham R.
core  

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Intimate partner violence and HIV: embracing complexity

The Lancet Global Health, 2015
Guy Harling, Alexander C Tsai, S V Subramanian   +2 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

House Unpassed Legislation 1918, H 45 committee on rules - referred to next General Court, SC1/series 230, Petition of Vincent E. Barnes

Petition subject: Court cases Original: http://nrs.harvard.edu/urn-3:FHCL:25763643 Date of creation: (unknown) Petition location: Massachusetts Legislator, committee, or address that the petition was sent to: Alvin E.
Digital Archive of Massachusetts Anti-Slavery and Anti-Segregation Petitions, Massachusetts Archives, Boston MA
core   +2 more sources

The contribution of social networks to the health and self-management of patients with long-term conditions: a longitudinal study

, 2014
Aim: to determine how the social networks of people with long-term conditions (diabetes and heart disease) are associated with health-related outcomes and changes in outcomes over time.Methods: patients with chronic heart disease (CHD) or diabetes (n ...
Vassilev, I., Christian Blickem, Christian Blickem (397641), Brooks Helen, Brooks, Helen; id_orcid, Anne Kennedy, Anne Rogers, Vassilev Ivaylo, Kennedy, A, Gerry Richardson (571072), Brooks, H., Vassilev, Ivaylo, Reeves, David, Helen Brooks, David Reeves, Richardson, G, Rogers, A, Reeves David, David Reeves (164641), Brooks, H, Reeves, D, Blickem Christian, Blickem, C, Ivaylo Vassilev (397639), Blickem, Christian, Anne Kennedy (397644), Rogers, Anne, Kennedy, Anne, Richardson, Gerry, Rogers Anne, Helen Brooks (397642), Ivaylo Vassilev, Anne Rogers (397640), Richardson Gerry, Vassilev, I, Kennedy Anne, Gerry Richardson   +36 more
core   +1 more source