Results 81 to 90 of about 2,939,571 (305)

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

TEST: A Tropic, Embodied, and Situated Theory of Cognition [PDF]

open access: yes, 2013
TEST is a novel taxonomy of knowledge representations based on three distinct hierarchically organized representational features: Tropism, Embodiment, and Situatedness.
Fischer, Martin   +3 more
core   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Boundary Spanning in Academia: Antecedents and Near-Term Consequences of Academic Entrepreneurialism [PDF]

open access: yes, 2013
Analyzing the pathways of people who earned interdisciplinary research doctorates in the United States in 2010, we generate three main findings while controlling for gender, ethnicity, discipline, and age.
Hanks, Andrew S, Kniffen, Kevin M
core   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Recovery from eating disorders: psychometric properties of a patient-related measure

open access: yesPatient Related Outcome Measures, 2012
Gunn Pettersen,1 Kari-Brith Thune-Larsen,2 Jan H Rosenvinge31Department of Health and Care Sciences, Faculty of Health Sciences, University of Tromsø, Tromsø, Norway; 2Oslo University Hospital, Oslo, Norway; 3Department of ...
Rosenvinge JH   +2 more
doaj  

Assessment of Post-COVID-19 Quality of Life Using the Quality of Life Index

open access: yesPatient Preference and Adherence, 2021
Maaidah M Algamdi Department of Nursing, Faculty of Applied Medical Sciences, University of Tabuk, Tabuk, Saudi ArabiaCorrespondence: Maaidah M AlgamdiDepartment of Nursing, Faculty of Applied Medical Sciences, University of Tabuk, Tabuk, Saudi ArabiaTel
Algamdi MM
doaj  

Centerscope [PDF]

open access: yes, 1981
Centerscope, formerly Scope, was published by the Boston University Medical Center "to communicate the concern of the Medical Center for the development and maintenance of improved health care in contemporary society.
Black, Paul H.
core   +1 more source

Finding a consensus between philosophy of applied and social sciences: A case of biology of human rights [PDF]

open access: yes, 2020
This paper is an attempt to provide an adequate theoretical framework to understand the biological basis of human rights. We argue that the skepticism about human rights is increasing especially among the most rational, innovative and productive ...
Younas, Ammar
core  

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

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