Results 101 to 110 of about 1,612,091 (336)

Halorotetin B, A Novel Terpenoid Compound Derived from Marine Ascidian, Suppresses Tumor Growth by Targeting the Cell Cycle Regulator UBE2C

open access: yesAdvanced Science, EarlyView.
Halorotetin B, a novel small‐molecule terpenoid identified from an edible marine ascidian, exhibits strong anti‐tumor activity both in vitro and in vivo through direct targeting UBE2C to induce tumor cell cycle arrest and then lead tumor cell senescence. As a newly discovered UBE2C inhibitor, Halorotetin B can serve as a novel potential cell senescence
Shanhao Han   +6 more
wiley   +1 more source

Organic farms as refuges for small mammal biodiversity in agro ecosystems [PDF]

open access: yes, 2011
Habitat fragmentation, the process by which relatively continuous habitats is broken into smaller pieces, occurs in natural systems but is to a high degree also human-induced through landscape use.
Hansen, Tine Sussi   +2 more
core  

DR5 Governs Compound Exocytosis in Colonic Goblet Cells via TATA‐Box Binding Protein‐Dependent Bestrophin‐2 Transcriptional Regulation

open access: yesAdvanced Science, EarlyView.
DR5 knockout exhibits a thinner colonic mucus layer, leading to mild dysbiosis, increased susceptibility to Citrobacter rodentium invasion, and exacerbated epithelial injury. Mechanistically, DR5 binds transcription factor TBP, which regulates the expression of gene Best2 via its promoter.
Ying Wang   +9 more
wiley   +1 more source

Ion‐Electron Fusion Transparent Film for Interactive Soft Robotics

open access: yesAdvanced Science, EarlyView.
An ion‐electron fusion transparent film with stable conductivity, high optical transmittance, and a broad linear strain‐sensing range of up to 300% is developed, attributed to the synergistic effects of ion penetration and microcrack design. When applied to soft robots, this film imparts proprioceptive sensing and underwater visible light communication
Zhiqiu Ye   +12 more
wiley   +1 more source

Encapsulating Textiles with Dynamic Covalent Networks for Sustainable and Efficient Oil Spill Cleanup

open access: yesAdvanced Science, EarlyView.
By encapsulating industrially relevant fabrics with dynamic imine networks, we show that the resulting composites exhibit exceptional oil absorbtion capability and chemical recyclability. It is poised for sustainable oil spill cleanup. ABSTRACT The development of high‐performance sorbents for oil spill remediation is highly desirable, which now calls ...
Changyi You   +9 more
wiley   +1 more source

Reconfigurable Acoustofluidic Microvortices for Selective Microcargo Delivery

open access: yesAdvanced Science, EarlyView.
This work introduces a frequency‐encoded, reconfigurable acoustofluidic system that overcomes the low throughput and poor selectivity of conventional micro‐delivery methods. By exploiting discrete microbubble resonances to program adaptive microvortex modes, the platform enables real‐time switching and selective guidance of microscale payloads through ...
Lei Wang   +6 more
wiley   +1 more source

Linking species habitat and past palaeoclimatic events to evolution of the teleost innate immune system [PDF]

open access: hybrid, 2017
Monica Hongrø Solbakken   +3 more
openalex   +1 more source

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