Results 111 to 120 of about 918,155 (301)

HD‐tDCS Restores Perivascular AQP4 Polarization via PPARγ Modulation to Enhance Glymphatic Clearance After Intracerebral Hemorrhage in Mice

open access: yesAdvanced Science, EarlyView.
HD‐tDCS promotes recovery after intracerebral hemorrhage by enhancing PPARγ‐dependent astrocyte remodeling in a mouse model of ICH. This process suppresses proinflammatory astrocytic activation, restores perivascular AQP4 repolarization, and improves glymphatic influx and efflux, thereby facilitating hematoma and perihematomal edema clearance and ...
Zhiming Li   +8 more
wiley   +1 more source

THE PATHOLOGY OF HABIT [PDF]

open access: yesBritish Journal of Inebriety, 1905
n ...
openaire   +1 more source

NSD2 Coordinates the Neurogenic‐to‐Gliogenic Transition via H3K36me2‐Dependent Activation of the EGFR‐ERK Pathway

open access: yesAdvanced Science, EarlyView.
NSD2 coordinates the neurogenic‐to‐gliogenic transition in the developing neocortex through H3K36me2‐dependent activation of EGFR–ERK signaling. Loss of NSD2 disrupts astroglial and oligodendroglial development, whereas ERK activation rescues gliogenic defects in vitro and in vivo.
Hanxue Chen   +7 more
wiley   +1 more source

Tomorrow Never Comes: The Risks of Procrastination for Adolescent Health

open access: yesEuropean Journal of Investigation in Health, Psychology and Education
This study explores the relationship between procrastination and declining healthy habits among adolescents, a topic lacking systematic reviews in the existing literature.
David Pérez-Jorge   +3 more
doaj   +1 more source

In Situ Profiling of Nanoscale Strains Uncovers Mechano‐Architectural Predictors of Aging and Osteoarthritis Emergence

open access: yesAdvanced Science, EarlyView.
In situ mechanical loading of osteoarthritis‐prone murine knee joints reveals that spatial alterations in subchondral plate microarchitecture precede cartilage loss and promote a shift from coordinated epiphyseal strain dissipation in healthy joints to focal subchondral strain concentration in osteoarthritis‐prone joints.
Aikta Sharma   +10 more
wiley   +1 more source

Loss of SHP1 in Spinal Astrocytes Triggers T‐Lymphocyte Infiltration and Nociceptive Hypersensitivity

open access: yesAdvanced Science, EarlyView.
Astrocyte‐specific SHP1 deletion disrupts astrocyte–vascular interactions and compromises BBB integrity while enhancing STAT1‐dependent CXCL10 expression. These changes synergistically promote peripheral CD4+ and CD8+ T‐cell infiltration into the SDH. The infiltrating T cells secrete IFN‐γ, which in turn activates microglia.
Lan‐Xing Yi   +7 more
wiley   +1 more source

Relationship between unilateral posterior crossbite and deleterious oral habits in preschool children from a municipality in southwestern Bahia

open access: yesRevista de Odontopediatria Latinoamericana, 2019
Objective: The objective of the study was to verify the prevalence of malocclusion in pre-school children in a municipality in southwest Bahia, focusing on the presence of unilateral posterior crossbite and its relation with deleterious oral habits ...
Alice Katarina Rosa Araújo Pina   +4 more
doaj  

Signatures of Perseveration and Heuristic-Based Directed Exploration in Two-Step Sequential Decision Task Behaviour

open access: yesComputational Psychiatry
Processes formalized in classic Reinforcement Learning (RL) theory, such as model-based (MB) control, habit formation, and exploration have proven fertile in cognitive and computational neuroscience, as well as computational psychiatry. Dysregulations in
Angela Mariele Brands   +2 more
doaj   +1 more source

Gestational Hypoxia Disrupts Medial Ganglionic Eminence Progenitor Dynamics and Interneuron Development in Schizophrenia

open access: yesAdvanced Science, EarlyView.
FES‐derived MGE spheroids exhibit progenitor‐stage alterations in developmental trajectory and hypoxia‐responsive transcriptional programs, followed by functional disruption. Gestational hypoxia recapitulates impaired progenitor proliferation, shortened cell‐cycle progression, interneuron developmental abnormalities, and schizophrenia‐like behaviors in
Peiyan Ni   +17 more
wiley   +1 more source

Driving dangerously: law, culture and driving habits in Iran

open access: yes, 2012
Iran has the highest rate of road traffic accidents (RTAs) worldwide. Iranian studies of the growing levels of RTAs are often conducted by medical doctors, who view them in light of the increase in the production and ownership of cars and the changed ...
Banakar, R., Nasrolahi Fard, S.
core   +1 more source

Home - About - Disclaimer - Privacy