Results 91 to 100 of about 1,228,072 (312)

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

RETRACTED: Comparison of the effect of dydrogesterone and natural micronized progesterone for luteal‐phase support in assisted reproductive technology cycles: A single‐blind randomized clinical trial study

Health Science Reports
Background and Aims One of the causes of preterm labor and recurrent abortion is progesterone deficiency in the luteal phase. The aim of the study was a comparison of the effect of oral dydrogesterone and vaginal progesterone for luteal‐phase support ...
Masoomeh Atarieh, Maryam Javadian, Zahra Basirat, Mehdi Kashifard, Shahla Yazdani, Hajar Adib‐Rad, Maryam Abdollahzade‐Delavar, Hemmat Gholinia   +7 more
doaj   +1 more source

Exploration of running in minimal and conventional footwear on tibial stress fracture probability in habitual and non-habitual minimal users

Baltic Journal of Health and Physical Activity
This research sought to investigate the impact of minimal and conventional footwear on the likelihood of tibial stress fractures among individuals who habitually and do not habitually use minimal footwear. Ten males who habitually ran in minimal footwear
Jonathan K. SINCLAIR, Paul J. TAYLOR
doaj   +1 more source

Influence of Estrogen Receptor α Polymorphisms on Bone Density in Response to Habitual Exercise in Japanese Postmenopausal Women

The Scientific World Journal, 2014
Estrogen receptor α (ERα) is one of candidate genes for osteoporosis. This study examined the influence of ERα gene, PvuII, and XbaI genotypes on bone density of calcaneus in response to habitual exercise.
Hiroyo Kondo, Hidemi Fujino, Fumiko Nagatomo, Akihiko Ishihara   +3 more
doaj   +1 more source

Evolutionary dynamics of the chloroplast genome in Daphne (Thymelaeaceae): comparative analysis with related genera and insights into phylogenetics

FEBS Open Bio, EarlyView.
Comparative analysis of chloroplast genomes from 14 genera of Thymelaeaceae revealed variation in gene content, ranging from 128 to 142 genes, primarily influenced by IR expansion/contraction events and pseudogenization of ndhF, ndhI, and ndhG. Two large inversions were detected within the large single‐copy region, including a synapomorphic inversion ...
Abdullah, Hui Li, Rushan Yan, Chengyu Chen, Madiha Islam, Abdul Majid, Ibrar Ahmed, Parviz Heidari, Xiaoxuan Tian   +8 more
wiley   +1 more source

Pharmacotherapy with Using Vitamins and Minerals of Idiopathic Habitual Miscarriage

Львівський клінічний вісник, 2014
Introduction. The presence in the history of two spontaneous miscarriages and more in the first trimester is treated as the usual miscarriage of pregnancy.
Markin L. , Kunynets H.
doaj   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Linux Security [PDF]

, 2017
Information age has brought a new colossal change in a person’s habitual life. The level of computer literacy has grown greatly and even a middle level specialist is able to perform the tasks intended for the programming experts.
Gubkina, V.V., Hryhorenko, Vladyslav, Mieshkov, V.I.   +2 more
core  

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

METABOLOMICS IN THE IDENTIFICATION OF BIOMARKERS OF DIETARY INTAKE

Computational and Structural Biotechnology Journal, 2013
Traditional methods for assessing dietary exposure can be unreliable, with under reporting one of the main problems. In an attempt to overcome such problems there is increasing interest in identifying biomarkers of dietary intake to provide a more ...
Aoife O'Gorman, Helena Gibbons, Lorraine Brennan   +2 more
doaj   +1 more source