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Goal-directed therapy: what is the goal again? [PDF]
Perioperative MedicineRecent attention has focused on intraoperative hypotension (IOH) and hemodynamic instability. This enhanced awareness to limit IOH, combined with fluid restriction and increased vasopressor use, has been associated with an increase in postoperative acute
Amy Yerdon +5 more
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Delayed rewards weaken human goal directed actions [PDF]
npj Science of LearningGoal-directed actions are sensitive to the causal association between actions and outcomes, as well as the value of those outcomes. Such sensitivity diminishes when actions become habitual.
Omar David Perez, Gonzalo P. Urcelay
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Neural correlates of goal-directed and non-goal-directed movements [PDF]
Proceedings of the National Academy of Sciences, 2019 AbstractWhat are the neural correlates that distinguish goal-directed (G) from non-goal-directed movements (nG)? We investigated this question in the monkey frontal eye field, which is implicated in voluntary control of saccades. We found that only for G-saccades, the variability in spike rate across trials decreased, the regularity of spike timings ...
Sendhilnathan, Naveen +4 more
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Frontiers in Medicine, 2022 BackgroundPost-operative delirium is common in elderly patients and associated with increased morbidity and mortality. We evaluated in this pilot study whether a perioperative goal-directed hemodynamic optimization algorithm improves cerebral oxygenation
Kristina E. Fuest +10 more
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Perioperative Goal-Directed Therapy [PDF]
Journal of Cardiothoracic and Vascular Anesthesia, 2014 From the Department of Anesthesiology, Duke University, Durham, North Carolina. T.E.M. is a consultant for Edwards Lifesciences, Covidien, and Hospira. Research funding from Cheetah Medical and Retia Medical. T.J.G. is a consultant for Baxter, Edwards Life Science, Hospira and QRx.
Waldron, Nathan H +2 more
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Neural processing of goal and non-goal-directed movements on the smartphone
NeuroImage: Reports, 2023 The discrete behavioral events captured on the smartphone touchscreen may help unravel real-world neural processing. We find that neural signals (EEG) surrounding a touchscreen event show a distinctly contralateral motor preparation followed by visual ...
Ruchella Kock +3 more
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Temporal hierarchy of observed goal-directed actions
Scientific Reports, 2023 During social interactions, we continuously integrate current and previous information over varying timescales to infer other people's action intentions.
Shahar Aberbach-Goodman, Roy Mukamel
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Brain Sciences, 2021 Shifting between goal-directed and habitual behaviors is essential for daily functioning. An inability to do so is associated with various clinical conditions, such as obsessive–compulsive disorder (OCD).
Maya Bar Or, Oded Klavir
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Neuromodulatory control of a goal-directed decision. [PDF]
PLoS ONE, 2014 Many cost-benefit decisions reduce to simple choices between approach or avoidance (or active disregard) to salient stimuli. Physiologically, critical factors in such decisions are modulators of the homeostatic neural networks that bias decision ...
Keiko Hirayama +3 more
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Goal salience affects infants’ goal-directed gaze shifts
Frontiers in Psychology, 2012 Around their first year of life, infants are able to anticipate the goal of others’ ongoing actions. For instance, 12-month-olds anticipate the goal of everyday feeding actions and manual actions such as reaching and grasping.
Ivanina eHenrichs +3 more
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