Results 61 to 70 of about 117,342 (294)

Habitus and Field

open access: yes, 2010
The terms habitus and field are useful heuristic devices for thinking about power relations in international studies. Habitus refers to a person’s taken-for-granted, unreflected—hence largely habitual—way of thinking and acting. The habitus is a “structuring structure” shaping understandings, attitudes, behavior, and the body.
openaire   +4 more sources

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

open access: yesFEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi   +2 more
wiley   +1 more source

An approach for coherent periodogram averaging of tilt‐series data for improved contrast transfer function estimation

open access: yesFEBS Open Bio, EarlyView.
The contrast transfer function (CTF) is an imaging aberration that is a major resolution‐limiting factor in cryo‐electron microscopy (cryo‐EM). Precise CTF estimation is key to overcoming this limitation, but is particularly challenging in cryo‐electron tomography (cryo‐ET) data. Here, we present an approach for using geometric information to assist in
Sagar Khavnekar, William Wan
wiley   +1 more source

LEXAMBIENTE Rivista Trimestrale di Diritto Penale dell’Ambiente Fasc. n. 4/2019 38 Il reato di trasporto di rifiuti (art. 256, 1° comma, d.lgs. 152/06): istantaneità vs permanenza The crime of transportation of waste (art. 256, 1st paragraph, d.lgs. 152/06): instantaneousness vs permanence

open access: yesLexambiente, 2019
The paper criticizes the Court of Cassation which qualifies the case of the illegal transport of waste (art. 256, 1st paragraph, Legislative Decree 152/06) as an instantaneous or, at the most, possibly habitual offense and instead affirms its nature ...
Vincenzo Paone
doaj  

Identifying prognostic targets in metastatic prostate cancer beyond AR

open access: yesFEBS Open Bio, EarlyView.
Genome‐wide functional screens combined with a large gene expression database and clinical outcomes can identify new therapeutic vulnerabilities in prostate cancer. Eight potentially druggable targets demonstrated strong dependency in cell lines, were associated with worse prognosis clinically, and showed evidence of protein expression in prostate ...
Emily Feng   +13 more
wiley   +1 more source

Influence of Estrogen Receptor α Polymorphisms on Bone Density in Response to Habitual Exercise in Japanese Postmenopausal Women

open access: yesThe Scientific World Journal, 2014
Estrogen receptor α (ERα) is one of candidate genes for osteoporosis. This study examined the influence of ERα gene, PvuII, and XbaI genotypes on bone density of calcaneus in response to habitual exercise.
Hiroyo Kondo   +3 more
doaj   +1 more source

Pharmacotherapy with Using Vitamins and Minerals of Idiopathic Habitual Miscarriage

open access: yesЛьвівський клінічний вісник, 2014
Introduction. The presence in the history of two spontaneous miscarriages and more in the first trimester is treated as the usual miscarriage of pregnancy.
Markin L. , Kunynets H.
doaj   +1 more source

Co‐overexpression of the caloric restriction‐induced mitochondrial factors PGC‐1α and MIPEP upregulates Phospho1 expression in adipocytes

open access: yesFEBS Open Bio, EarlyView.
Caloric restriction that extends lifespan induces the expression of PGC‐1α and MIPEP in white adipose tissue. In this study, co‐overexpression of Pgc‐1α and Mipep upregulated the gene expression of PHOSPHO1. These findings provide new insights into mitochondria‐related mechanisms underlying the effects of caloric restriction in adipocytes.
Mamiko Ishimatsu   +9 more
wiley   +1 more source

The E3 ubiquitin ligase, RNF219, suppresses CNOT6L expression to exhibit antiproliferative activity

open access: yesFEBS Open Bio, EarlyView.
We identified RNF219 as a CCR4‐NOT complex‐interacting E3 ubiquitin ligase that targets the CCR4‐NOT subunit CNOT6L for ubiquitination. RNF219 directly binds to the DUF3819 domain of CNOT1 through its putative α‐helix spanning amino acids 521–542. Our findings also suggest that antiproliferative activity of RNF219 is at least partially mediated by ...
Shou Soeda   +9 more
wiley   +1 more source

Motivational salience drives habitual gazes during value memory retention and facilitates relearning of forgotten value

open access: yesiScience, 2022
Summary: A habitual gaze is critical to efficiently identify and exploit valuable objects. However, it is unclear what salience components drive the habitual gaze choice.
Seong-Hwan Hwang   +3 more
doaj  

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