Results 51 to 60 of about 250,996 (256)

Antiphospholipid syndrome and pregnancy—a hematologic perspective

Research and Practice in Thrombosis and Haemostasis
A state-of-the-art lecture entitled “APS and pregnancy: a haematologic perspective” was presented at the International Society on Thrombosis and Haemostasis (ISTH) Congress in 2025.
Andrew J. Doyle, Catrin Cox, Karen A. Breen   +2 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Estilo de vida de pré-vestibulandos da cidade de Lages/SC: nível de atividade física habitual, vulnerabilidade ao estresse e hábitos alimentares [PDF]

, 2002
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Desportos. Programa de Pós-Graduação em Educação Física.O objetivo principal deste estudo foi observar o estilo de vida dos pré-vestibulandos da cidade de Lages/SC, no que se ...
Marcon, Marcelo Alexandre
core  

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Teachers' use of reported habitual thoughts in research interviews

Use of reported thoughts in research interviews has rarely been examined although research interviews are a major source of data in qualitative research.
Edwards-Groves, Christine, Davidson, Christina   +1 more
core   +1 more source

On the incompatibility of object fronting and progressive aspect in Yucatec Maya

Frontiers in Language Sciences
In this paper, we present data from an elicitation study and a corpus study that support the observation that the Yucatec Maya progressive aspect auxiliary táan is replaced by the habitual auxiliary k in sentences with contrastively focused fronted ...
Melanie Uth, Rodrigo Gutiérrez-Bravo, Jan Fliessbach   +2 more
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

"The rate of Chlamydia Trachomatis, Mycoplasma Hominis and Ureaplasma Urealyticum in females with habitual abortion and its comparison with control group " [PDF]

Acta Medica Iranica, 2002
Females abortion is one of the most important sequela of genital infection with chlamydia trachomatis, Mycoplasma hominis and Ureaplasma urealyticum.In this study frequency of Chlamydia trachomatis, Mycoplasma hominis and Ureaplasma urealyticum was ...
Salari MH, Badami N
doaj   +1 more source

From LIKE/LOVE to habitual: the case of Mainland East and Southeast Asian languages

Linguistics
This paper documents the common grammaticalization path of the LIKE/LOVE constructions into expressing habitual aspect in Mainland East and Southeast Asian languages. The stages and degrees of grammaticalization for the LIKE/LOVE constructions vary cross-
Fang Hongmei
doaj   +1 more source