Results 61 to 70 of about 250,996 (256)

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

In conversation with habitual entrepreneurs [PDF]

open access: yes, 2019
In 2000 and 2001 a team at the University of Surrey researched best practice in small businesses in hospitality and tourism as part of the ‘Profit through productivity’ initiative.
Bowen, Andrea   +2 more
core   +1 more source

Hubungan Habitual Snoring dengan Prestasi Akademis Anak Sekolah Dasar

open access: yesSari Pediatri, 2016
Latar belakang. Habitual snoring dapat menimbulkan berbagai komplikasi. Berbagai penelitian menunjukkan terdapat hubungan antara habitual snoring dengan prestasi akademis anak yang rendah, tetapi belum terdapat penelitian mengenai hal ini di Indonesia ...
Hendri Tanu Jaya   +2 more
doaj   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

Atividade física habitual e desempenho motor de indivíduos com e sem a doença de Parkinson [PDF]

open access: yes, 2012
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Desportos, Programa de Pós-Graduação em Educação Física, Florianópolis, 2011Objetivo: Descrever a atividade física habitual e sua associação com o desempenho motor em indivíduos ...
Guimarães, Alexsander Vieira
core  

Caffeine promotes global spatial processing in habitual and non-habitual caffeine consumers

open access: yesFrontiers in Human Neuroscience, 2013
Information processing is generally biased toward global cues, often at the expense of local information. Equivocal extant data suggests that arousal states may accentuate either a local or global processing bias, at least partially dependent on the ...
Grace E. Giles   +4 more
doaj   +1 more source

Level of habitual physical activity and parameters of the cardio-respiratory system in students

open access: yesСпортивная медицина: наука и практика, 2020
Objective: to analyze the parameters of the cardio-respiratory system in healthy students with different levels of habitual physical activity. Materials and methods: 106 students of Tula State University (61W, 45M, mean age - 22.9±0.4 years (M±m), mean ...
N. Tsarev, Y. Venevtseva
doaj   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

open access: yesMolecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler   +3 more
wiley   +1 more source

Effect of the reinforcement rate on goal-directed and habitual choices in a multiple schedule

open access: yesFrontiers in Psychology
Voluntary behaviors can be either goal-directed, sensitive to changes in their consequences, or habitual, lacking such sensitivity. In this study, we conducted three experiments to investigate how forced-choice training influences goal-directed and ...
Ting Hu   +4 more
doaj   +1 more source

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