Results 81 to 90 of about 4,030 (202)

Using an Adapted Job Demands–Resources Model to Examine the Use of Legal, Prescription, and Illegal Drugs for Cognitive Enhancement in the Working Population in Germany

open access: yesSociological Inquiry, EarlyView.
Chronic stress is a global issue with detrimental effects on health and productivity, often leading individuals to adopt health‐related coping strategies. This study uses an adapted Job Demands–Resources model to examine how various job demands and resources impact perceived stress and, consequently, the use of legal, prescription, and illegal drugs ...
Sebastian Sattler   +3 more
wiley   +1 more source

Three-layer circulation in the world deepest hadal trench. [PDF]

open access: yesNat Commun
The Challenger Deep (CD) is the deepest known hadal trench in the world. Due to challenges in data sampling at extreme ocean depths, the Lower Circumpolar Deep Water (LCDW) transport and ocean circulation structure in the CD remain unclear. By analyzing data from an extra-deep current meter mooring array, here we find a three-layer circulation in the ...
Jiang H   +8 more
europepmc   +4 more sources

Differential effect of lead and cadmium on mitochondrial function and NLRP3 inflammasome activation in human trophoblast

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend The human placenta not only detects the presence of Pb and Cd but also carries hypoxia and inflammatory risks, which are associated with pregnancy complications. To understand the impact of these factors on the placental trophoblast, we evaluated the effect of Pb and Cd on mitochondrial function and the NLRP3 inflammasome in ...
Yifeng Dai   +4 more
wiley   +1 more source

Calciprotein particle‐induced calcium overload triggers mitochondrial dysfunction in endothelial cells

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Calciprotein particles (CPPs) are small calcium‐ and phosphate‐containing nanoaggregates associated with the development of vascular disease (CVD) in chronic kidney disease (CKD). Previously, we have shown that CPPs induce endothelial cell (EC) dysfunction, possibly contributing to CVD in CKD, but the underlying molecular ...
Lian Feenstra   +9 more
wiley   +1 more source

Bridging the gap: Co‐produced neurodiversity‐affirming resources for undiagnosed children aged 7–11: Insights from children, families and stakeholders

open access: yesJournal of Research in Special Educational Needs, Volume 26, Issue 2, April 2026.
Abstract This qualitative study investigated the acceptability and suitability of neurodiversity‐affirming psychoeducational resources for children aged 7–11 years without formal autism or attention deficit hyperactivity disorder (ADHD) diagnoses. Using a reflexive thematic analysis of semi‐structured interviews with 24 families and written feedback ...
E. Shore, L. Powell
wiley   +1 more source

Genome Reduction in Psychromonas Species within the Gut of an Amphipod from the Ocean’s Deepest Point

open access: yesmSystems, 2018
Amphipods are the dominant scavenging metazoan species in the Mariana Trench, the deepest known point in Earth’s oceans. Here the gut microbiota of the amphipod Hirondellea gigas collected from the Challenger and Sirena Deeps of the Mariana Trench were ...
Weipeng Zhang   +13 more
doaj   +1 more source

Infants' General Movements Were Not Affected by Exposure to Maternal Severe Acute Respiratory Syndrome Coronavirus 2 Infections

open access: yesActa Paediatrica, Volume 115, Issue 4, Page 913-922, April 2026.
ABSTRACT Aim Prenatal maternal infections may impair infant brain development. This study investigated the effect of maternal infections with the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) during pregnancy on infant neurodevelopment by assessing general movements (GMs).
Kathrin Neumayr   +14 more
wiley   +1 more source

Cameras and carcasses: historical and current methods for using artificial food falls to study deep-water animals [PDF]

open access: yes, 2007
Deep-ocean animals remain poorly understood compared to their shallow-water relatives, mainly because of the great cost and difficulty involved in obtaining reliable ecological data.
Bailey, D.M., King, N.J., Priede, I.G.
core   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, Volume 20, Issue 3, Page 779-803, March 2026.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Ocean Worlds : May 21–23, 2018, Houston, Texas [PDF]

open access: yes, 2018
The focus will be on the potential for silicate-water interactions to occur on Ocean Worlds beyond Earth, from a multi-disciplinary and inter-disciplinary perspective.Organizers Lunar and Planetary Institute, Universities Space Research Association ...

core  

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