Results 141 to 150 of about 13,881 (340)
Clonal haematopoiesis, ageing and kidney disease.
Nature Reviews Nephrology, 2023 C. Vlasschaert +4 more
semanticscholar +1 more source
Advanced Science, EarlyView.This study uses gut microbiome data to predict corticosteroid response in patients with immune thrombocytopenia (ITP). Fecal samples from 212 patients with ITP are sequenced. Six machine‐learning algorithms are used to train predictive models. The support vector machine‐based model integrated clinical data and selected microbial species, diversities ...
Feng‐Qi Liu +38 more
wiley +1 more source
Animal Models and Experimental Medicine, Volume 5, Issue 6, Page 542-549, December 2022., 2022 Schematic diagram showing RHAU can bind and unwind the G4 “knots” to modulate embryonic development and post‐natal organ function. Deficiency of RHAU gives rise to embryonic lethality, impaired organogenesis and organ dysfunction. RHAU modulates Nkx2‐5 mRNA and Yap1 mRNA at the post‐transcriptional level and facilitates the transcription of c‐Kit and ...
Chensi Yang +5 more
wiley +1 more source
Single-cell multi-omics and lineage tracing to dissect cell fate decision-making
Stem Cell Reports, 2023 Summary: The concept of cell fate relates to the future identity of a cell, and its daughters, which is obtained via cell differentiation and division. Understanding, predicting, and manipulating cell fate has been a long-sought goal of developmental and
Laleh Haghverdi, Leif S. Ludwig
doaj
Mitochondrial oxygen consumption and ineffective haematopoiesis in patients with myelodysplastic syndromes [PDF]
, 2002 David Bowen, Clare Peddie
openalex +1 more source
HNF3α Targets Nckap1l and Promotes Renal Fibrosis Following Ischemia‐Reperfusion Injury
Advanced Science, EarlyView.Hepatocyte Nuclear Factor 3 alpha (HNF3α) is significantly upregulated in renal tubular epithelial cells of CKD patients and fibrotic mice. Deletion of HNF3α mitigates IRI‐induced renal fibrosis, while overexpression worsens it. HNF3α directly regulates NCK‐associated protein 1‐like (Nckap1l), whose overexpression exacerbates fibrosis.
Ling Hou +7 more
wiley +1 more source
The protective effects of Xuebijing injection on intestinal injuries of mice exposed to irradiation
Animal Models and Experimental Medicine, Volume 5, Issue 6, Page 565-574, December 2022., 2022 Xuebijing injections (XBJ) is a traditional Chinese medicine (TCM), approved for the sepsis treatment of by the China Food and Drug Administration. XBJ can effectively enhance the mice survival rate after total body irradiation (TBI). XBJ protects the crypt‐villus structure, maintains the proliferation and differentiation of the small intestine after ...
Yinping Dong +9 more
wiley +1 more source
Suppression of haematopoiesis during therapy of chronic hepatitis C with different interferon mono and combination therapy regimens [PDF]
, 2005 M Schmid
openalex +1 more source
Advanced Science, EarlyView.UniMap introduces a novel multiselective adversarial network that functions as a discerner in single‐cell dataset integration. It enables type‐level integration, ensuring accurate cell type annotation across diverse biological contexts while preserving shared and domain‐specific features.
Haitao Hu +11 more
wiley +1 more source
Frontiers in Tropical DiseasesThe parasitic worm-derived immunomodulator, ES-62 rescues defective levels of IL-10-producing regulatory B cells (Bregs) and suppresses chronic Th1/Th17-driven inflammation to protect against joint destruction in the mouse collagen-induced arthritis (CIA)
Margaret M. Harnett +9 more
doaj +1 more source