Results 151 to 160 of about 14,069 (340)
FLASH Irradiation Modulates Immune Responses and Accelerates Lung Recovery: A Single‐Cell Perspective
Advanced Science, EarlyView.Single‐cell RNA sequencing reveals distinct immune responses to FLASH versus conventional dose rate irradiation in early radiation‐induced lung injury. FLASH irradiation reduces Ccrl2⁺ neutrophil infiltration, activates CD4⁺ CD40L⁺ Th cells, restrains pro‐inflammatory Mefv⁺ monocytes, and enhances epithelial repair via TGF‐β signaling, underscoring its Hao Lu, Menghua Li, Cheng Quan, Caihui Li, Dawei Li, Zhihui Li, Jing Xu, Lihui Zhang, Qixiang Liu, Guofu Dong, Changzhen Wang +10 morewiley +1 more sourceHistone Demethylase UTX Suppresses Tumor Cell Proliferation by Regulating Stress Granules
Advanced Science, EarlyView.These findings indicate that cytoplasmic UTX forms puncta and co‐localizes in stress granules (SGs) upon various stresses. UTX TPR‐domain‐dependently and demethylase‐activity‐independently destabilize SGs by binding G3BP1, the SG hub protein, to disrupt SG network, thus affects tumorigenesis.Xikai Liu, Xinran Liu, Mei Xue, Yushuo Xiao, Yuchen Chen, Rong Qiu, Di Wu, Yihao Zhou, Jiao Wang, Yan Yuan, Linwei Yu, Tianyi Shi, Yangkai Li, Hua Su, Hong Chen, Yong Liu, Kun Huang, Ling Zheng +17 morewiley +1 more sourcePrevalence and prognostic significance of DNMT3A- and TET2- clonal haematopoiesis-driver mutations in patients presenting with ST-segment elevation myocardial infarction
EBioMedicine, 2022 Sheng-yi Wang, Sining Hu, Xing Luo, Xiaoyi Bao, Ji Li, Minghao Liu, Ying Lv, Chen Zhao, Ming Zeng, Xi Chen, Amanda J. Unsworth, Sarah Jones, Thomas W. Johnson, Stephen White, H. Jia, Bo Yu +15 moresemanticscholar +1 more sourceBionic Nanostructures Create Mechanical Signals to Mediate the Composite Structural Bone Regeneration Through Multi‐System Regulation
Advanced Science, EarlyView.Inspired by the structural and functional characteristics of bone, bionic nanomaterials combined with nanotechnology can more accurately replicate stem cell niches, enabling the design of bone tissue engineering scaffolds with diverse nanoscale properties to promote stem cell migration, proliferation, and differentiation. This precise control over stem Yangfan Pei, Yihan Wang, Jingxia Chen, Jing Zhou, Yuzhu Han, Xiuyu Liu, Siyu Chen, Sheng Chen, Dixin He, Yunxiao Wu, Huixin Lv, Yanmin Zhou +11 morewiley +1 more sourceInherited causes of clonal haematopoiesis in 97,691 whole genomes
Nature, 2020 A. Bick, J. Weinstock, Satish K. Nandakumar, C. Fulco, Erik L. Bao, S. Zekavat, M. Szeto, Xiaotian Liao, Matthew J. Leventhal, J. Nasser, K. Chang, C. Laurie, B. Burugula, C. Gibson, A. Niroula, A. E. Lin, M. Taub, F. Aguet, K. Ardlie, B. Mitchell, K. Barnes, A. Moscati, M. Fornage, S. Redline, B. Psaty, E. Silverman, S. Weiss, Nicholette D. Palmer, R. Vasan, E. Burchard, S. Kardia, Jiang He, R. Kaplan, N. Smith, D. Arnett, D. A. Schwartz, A. Correa, M. de Andrade, Xiuqing Guo, B. Konkle, B. Custer, J. Peralta, H. Gui, D. Meyers, S. McGarvey, I. Chen, M. B. Shoemaker, P. Peyser, J. Broome, S. Gogarten, F. Wang, Q. Wong, M. Montasser, M. Daya, E. Kenny, K. North, L. Launer, B. Cade, J. Bis, M. Cho, J. Lasky-Su, Don Bowden, L. Cupples, Angel C. Y. Mak, L. Becker, Jennifer A. Smith, T. Kelly, Stella Aslibekyan, S. Heckbert, Hemant K. Tiwari, Ivana V. Yang, J. Heit, S. Lubitz, J. Johnsen, J. Curran, S. Wenzel, D. Weeks, D. Rao, D. Darbar, Jee-Young Moon, R. Tracy, Erin Buth, N. Rafaels, R. Loos, P. Durda, Yongmei Liu, L. Hou, Jiwon Lee, P. Kachroo, B. Freedman, D. Levy, Larry Bielak, J. Hixson, J. Floyd, E. Whitsel, P. Ellinor, M. Irvin, T. Fingerlin, L. Raffield, Sebastian M. Armasu, Marsha M. Wheeler, E. Sabino, J. Blangero, L. Williams, B. Levy, W. Sheu, D. Roden, E. Boerwinkle, J. Manson, R. Mathias, Pinkal M. Desai, K. Taylor, Andrew D. Johnson, Namiko Christine Laura Alvaro Seth Peter Pramod Deborah D Abe Albert Almasy Alonso Ament Anderson Anugu Appl, Namiko Abe, Christine Albert, L. Almasy, Álvaro Alonso, S. Ament, Peter Anderson, Pramod Anugu, Deborah Applebaum-Bowden, D. Arking, Allison Ashley-Koch, Stella Aslibekyan, T. Assimes, D. Avramopoulos, J. Barnard, R. G. Barr, E. Barron-Casella, L. Barwick, Terri L Beaty, Gerald Beck, D. Becker, Rebecca Beer, A. Beitelshees, E. Benjamin, P. Benos, Marcos Bezerra, Larry Bielak, Russell P Bowler, Jennifer A. Brody, U. Broeckel, Karen L. Bunting, Carlos Bustamante, J. Cardwell, V. Carey, C. Carty, R. Casaburi, James M. Casella, P. Castaldi, M. Chaffin, Christy Chang, Yi-Cheng Chang, D. Chasman, S. Chavan, Bo-Juen Chen, Wei-Min Chen, S. Choi, Lee-Ming Chuang, M. Chung, R. Chung, C. Clish, S. Comhair, E. Cornell, Carolyn Crandall, J. Crapo, J. Curtis, C. Damcott, Sayantan Das, S. David, Colleen Davis, Michael R. DeBaun, R. Deka, D. Demeo, Scott Devine, Qing Duan, R. Duggirala, S. Dutcher, Charles B. Eaton, L. Ekunwe, A. Boueiz, L. Emery, S. Erzurum, Charles Farber, M. Flickinger, N. Franceschini, C. Frazar, Mao Fu, Stephanie M. Fullerton, L. Fulton, S. Gabriel, Weiniu Gan, Shanshan Gao, Yan Gao, Margery Gass, B. Gelb, Xiaoqi (Priscilla) Geng, M. Geraci, S. Germer, R. Gerszten, Auyon J. Ghosh, Richard Gibbs, Christopher R. Gignoux, M. Gladwin, David E. Glahn, Daoping Gong, H. Goring, S. Graw, Daniel Grine, C. Gu, Y. Guan, N. Gupta, J. Haessler, Michael Hall, Daniel Harris, N. Hawley, Benjamin D. Heavner, Ryan Hernandez, David M. Herrington, C. Hersh, Bertha A Hidalgo, B. Hobbs, J. Hokanson, Elliott Hong, Karin Hoth, Chao (Agnes) Hsiung, Y. Hung, H. Huston, C. Hwu, Rebecca Jackson, D. Jain, C. Jaquish, Min A. Jhun, Craig Johnson, R. Johnston, Kimberly Jones, H. M. Kang, Shannon Kelly, Michael D. Kessler, Alyna T Khan, Wonji Kim, G. Kinney, Holly Kramer, C. Lange, M. LeBoff, S. Lee, Wen-Jane Lee, J. Lefaive, David Levine, J. Lewis, Xiaohui Li, Yun Li, Henry Lin, Honghuang Lin, Keng-Han Lin, Xihong Lin, Simin Liu, Yu Liu, K. Lunetta, James Luo, Michael P. Mahaney, B. Make, A. Manichaikul, L. Margolin, Lisa Martin, S. Mathai, Susanne May, P. McArdle, Merry-Lynn N. McDonald, Sean McFarland, Daniel McGoldrick, Caitlin P. McHugh, H. Mei, L. Mestroni, Julie Mikulla, N. Min, Mollie A Minear, R. Minster, M. Moll, C. Montgomery, S. Musani, Stanford E. Mwasongwe, J. Mychaleckyj, Girish N. Nadkarni, Rakhi Naik, T. Naseri, S. Nekhai, Sarah C. Nelson, Bonnie Neltner, D. Nickerson, Jeffery R O'connell, T. O'Connor, H. Ochs-Balcom, David T. Paik, J. Pankow, G. Papanicolaou, A. Parsa, Marco V. Perez, James Perry, U. Peters, P. Peyser, Lawrence S. Phillips, T. Pollin, Wendy S. Post, Julia Powers Becker, M. Boorgula, Michael H. Preuss, P. Qasba, D. Qiao, Zhaohui Qin, L. Rasmussen-Torvik, A. Ratan, Robert Reed, E. Regan, Muagututi’a Sefuiva Reupena, Kenneth M. Rice, C. Roselli, I. Ruczinski, Pamela H. Russell, S. Ruuska, K. Ryan, D. Saleheen, S. Salimi, Steven Salzberg, Kevin Sandow, Christopher Scheller, Ellen M. Schmidt, K. Schwander, F. Sciurba, C. Seidman, J. Seidman, V. Sheehan, Stephanie L. Sherman, Amol Shetty, Aniket Shetty, Brian Silver, Josh Smith, Tanja Smith, S. Smoller, B. Snively, M. Snyder, T. Sofer, N. Sotoodehnia, A. Stilp, G. Storm, E. Streeten, J. Su, Y. Sung, Jody Sylvia, Adam A. Szpiro, C. Sztalryd, D. Taliun, Hua Tang, M. Taylor, Simeon I. Taylor, M. Telen, T. Thornton, M. Threlkeld, Lesley Tinker, D. Tirschwell, S. Tishkoff, Hemant K. Tiwari, Catherine Tong, Michael Tsai, Dhananjay Vaidya, D. V. Berg, Peter Vandehaar, S. Vrieze, Tarik Walker, R. Wallace, A. Walts, Heming Wang, K. Watson, Bruce Weir, L. Weng, J. Wessel, C. Willer, Kayleen Williams, Carla Wilson, Joseph Wu, Huichun Xu, L. Yanek, Rongze Yang, N. Zaghloul, Yingze Zhang, Snow Xueyan Zhao, Wei Zhao, Degui Zhi, Xiang Zhou, Xiaofeng Zhu, M. Zody, S. Zoellner, P. Auer, C. Kooperberg, Cathy C. Laurie, T. Blackwell, A. Smith, Hongyu Zhao, E. Lange, L. Lange, S. Rich, J. Rotter, James G. Wilson, P. Scheet, J. Kitzman, E. Lander, J. Engreitz, B. Ebert, A. Reiner, S. Jaiswal, G. Abecasis, V. Sankaran, S. Kathiresan, P. Natarajan +414 moresemanticscholar +1 more source
