Results 151 to 160 of about 10,512 (289)

Transcription factor PBX4 regulates limb development and haematopoiesis in mice [PDF]

Yan Ning, Shuguang Duo, Xiwen Lin, Hongbo Zhang, Ji‐Feng Fei, Bao Zhang, Yanyun Zeng, Dan Xie, Jian Chen, Xiaowei Liu, Chunsheng Han   +10 more
openalex   +1 more source

LMO7 Suppresses Tumor‐Associated Macrophage Phagocytosis of Tumor Cells Through Degradation of LRP1

Advanced Science, EarlyView.
LMO7 in tumor‐associated macrophages suppresses phagocytosis of tumor cells and limits cytotoxic T lymphocytes infiltration, fostering tumor progression. Mechanistically, LMO7 mediates the ubiquitination and degradation of the phagocytic receptor LRP1, impairing its ability to engulf tumor cells and driving macrophages toward an antitumor phenotype ...
Mengkai Li, Tao Wang, Yuwen Zhong, Zhiming Wang, Wei Li, Zejian Wang, Xinyi Yang, Yu Qiao, Jianfeng Xiang, Wei Gu, Zishu Wang, Lei Sun, Feng Qian   +12 more
wiley   +1 more source

Editorial: Plasticity of the haematopoietic niche: from embryonic development to aging and disease. [PDF]

Front Mol Biosci
Sugimura R, Fidanza A, Azzoni E, Canu G.
europepmc   +1 more source

Promiscuous and lineage-specific roles of cell cycle regulators in haematopoiesis. [PDF]

, 2007
Stephen S. Myatt, Eric W.‐F. Lam
openalex   +1 more source

CDK4/6 Inhibition Induces CD8+ T Cell Antitumor Immunity via MIF‐Induced Functional Orchestration of Tumor‐Associated Macrophages

Advanced Science, EarlyView.
CDK4/6 inhibition promotes CD8+ T cell expansion through tumor‐macrophage crosstalk by activating HIF‐1α and enhancing MIF‐CD44/CD74 signaling. This reprograms TAMs to boost MHC‐I antigen presentation, and CDK4/6 inhibitor‐trained M1 TAM supernatant therapy synergizes with low‐dose PD‐1 blockade to restore antitumor immunity.
Lin He, Yuzhong Peng, Lat‐lun Leong, Jingbo Zhou, Dongyang Tang, Weilu Wang, Xiaoran Wu, Josh haipeng Lei, Yongqin Ye, Yangyang Feng, Yunfeng Qiao, Xiangpeng Chu, Di Mu, Qi Zhao, Tzuming Liu, Yan Chen, Paul Kwonghang Tam, Chu‐Xia Deng   +17 more
wiley   +1 more source

Western lifestyle linked to maladaptive trained immunity. [PDF]

Elife
Merbecks AJ, Mennicken C, de Graaf DM, Shkarina K, Wagner T, Latz E.   +5 more
europepmc   +1 more source

Red Blood Cells Internalize Extracellular DNA via Apoptotic Bodies with Clinical Relevance to Cancer Patients

Advanced Science, EarlyView.
Mature red blood cells (RBCs) can capture extracellular DNA, with short fragments homologous to cfDNA. This uptake is mediated by apoptotic bodies, which induce RBC oxidative stress, deformation, and accelerated in vivo clearance. The rbcDNA abundance correlates with tumor burden and therapeutic response, highlighting its potential as a liquid biopsy ...
Zihang Zeng, Zongbi Yi, Jing Hu, Jiali Li, Yu Xu, Xiuli Guo, Qian Ji, Kaixiang Feng, Ying Zhang, Sirui Bai, Yushuang Tan, Yufei Yan, Linzhi Han, Jing Jiang, Tengfei Wang, Xiang Wang, Ziqing Zhan, Ruiying Huang, Jinfang Zhang, Conghua Xie, Binghe Xu   +20 more
wiley   +1 more source

Discovery of New Markers for Haemogenic Endothelium and Haematopoietic Progenitors in the Mouse Yolk Sac. [PDF]

J Dev Biol
Diez-Pinel G, Muratore A, Ruhrberg C, Canu G.   +3 more
europepmc   +1 more source

Role of PDGF-B/PDGFR: signalling in definitive haematopoiesis

, 2020
Diana Sá da Bandeira
openalex   +1 more source

Normal development of fetal hepatic haematopoiesis during the second trimester of gestation is upregulated by fibronectin expression in the stromal cells of the portal triads [PDF]

, 2007
D Tamiolakis, Ioannis Venizelos, S. Nikolaidou, T. Jivanakis   +3 more
openalex   +1 more source