Results 221 to 230 of about 212,248 (255)

Healthcare-community partnership to improve nutrition insecurity for optimal glycaemic control and pregnancy outcomes in women with pregestational diabetes: clinical trial protocol for the NOURISH study. [PDF]

BMJ Open
Venkatesh KK, Joseph JJ, Headings A, Gillespie S, Garner J, Brock GN, Seiber E, Wu J, Kutay H, Parsons J, Shrodes J, Fonge A, Sawyer L, Shilling E, Vickers S, Remley D, Clark A, Baker C, Bartholomew A, Summerfield T, Grobman WA, Walker S, Field C, Walker D.   +23 more
europepmc   +1 more source

Engineered Cyanobacteria‐Hydrogel Microecological System for Oxygen Reprogramming Synergizes Immunomodulation With Anabolism in Osteoarthritis Therapy

Advanced Science, EarlyView.
An injectable cyanobacteria‐laden hydrogel enables light‐dependent oxygen metabolism engineering for osteoarthritis therapy. Photosynthetic oxygen release under red light irradiation suppresses synovial inflammation via HIF‐1α inhibition and M2 macrophage polarization, while respiratory oxygen consumption in darkness stabilizes chondrocyte HIF‐1α to ...
Lerong Yang, Chong Shen, Hongjun Huang, Siyi Liu, Zeyu Huang, Licheng Xi, Huan Cao, Li Zheng, Zainen Qin   +8 more
wiley   +1 more source

p-Chloroaniline - Derivation of a BAR: Assessment Values in Biological Material - Translation of the German version from 2026. [PDF]

MAK Collect Occup Health Saf
Schönrath I, Leng G, Drexler H, Hartwig A, MAK Commission.   +4 more
europepmc   +1 more source

Overcoming Drug Resistance by Paclitaxel Resistance in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
In the murine triple‐negative breast cancer (TNBC) model, chemotherapy effectively increases tumor neoantigen burden (TNB). Here, the study constructs a liposomal nanovaccine using antigens derived from in vitro chemotherapy‐treated paclitaxel‐resistant TNBC 4T1 cells.
Bo Chen, Yangyi Wang, Tingting Li, Changqing Guo, Zhe Xie, Zhixian Zhang, Xinghua Han, Wei Wang, Jian Wang, Xiaopeng Ma, Yuanzeng Min   +10 more
wiley   +1 more source

Switching Spike Plasticity Shapes ACE2 Engagement Across SARS‐CoV‐2 Variants

Advanced Science, EarlyView.
Conformational plasticity governs SARS‐CoV‐2 spike function and ACE2 recognition. Using high‐speed AFM and single‐molecule force spectroscopy, we analyzed the ancestral spike and nine variants, revealing progressive rigidification from Delta, variable plasticity in Omicron sublineages, and JN.1 compaction.
Sarah Stainer, Rong Zhu, Manuel Reithofer, Gerhard Stadlmayr, Katharina Stadlbauer, Panchika Prangkio, Christoph Rippel, Markus Hahn, Aniko Eva Kasztner, Stefanie Stohl, Petr Bednar, Daniel Ruzek, David Glück, Robert Tampé, Gordana Wozniak‐Knopp, Yoo Jin Oh, Miriam Klausberger, Peter Hinterdorfer   +17 more
wiley   +1 more source

Haematological pre-staging of colorectal cancer: Longitudinal trends identify high-risk metastatic phenotypes 24 months prior to diagnosis. [PDF]

Transl Oncol
Sala RJ, Ery J, Cuesta-Peredo D, Muedra V, Rodilla V.   +4 more
europepmc   +1 more source

Translational Barriers and AI‐Driven Challenges of Microfluidics‐Enabled Wearables and Implantable Systems in Personalized Medicine

Advanced Science, EarlyView.
An integrative review of microfluidics‐enabled wearables and implantable systems reveals a single‐track translation pipeline, bridging functional biomaterials with clinical utility. Dynamic feedback loops driven by artificial intelligence advance diagnostics toward personalized closed‐loop theranostics.
Ke Huang, Ching Yin Fong, Xin Huang, Bee Luan Khoo   +3 more
wiley   +1 more source

Early-onset, treatment-cycle-linked hyperinsulinaemic insulin resistance during capivasertib therapy: a case report. [PDF]

Cardiovasc Diabetol Endocrinol Rep
Motai Y, Nakamura S, Sekine N, Sugimoto D, Satoh H.   +4 more
europepmc   +1 more source

Antenatal maternal anaemia and infant brain structure: high-field (3 T) and ultra-low-field (64 mT) MRI findings from South Africa. [PDF]

Brain Commun
Ringshaw JE, Zieff MR, Bourke NJ, Casella C, Bradford LE, Williams SR, Herr D, Miles M, Bennallick C, Khula South Africa Data Collection Team, Deoni S, O'Muircheartaigh J, Stein DJ, Alexander DC, Jones DK, Williams SCR, Donald KA, Khula South Africa Data Collection Team .   +17 more
europepmc   +1 more source