Results 201 to 210 of about 298,827 (312)

Impact of Preoperative Anaemia on Blood Transfusion and Clinical Outcomes in Total Knee Arthroplasty: A Retrospective Observational Study. [PDF]

Turk J Anaesthesiol Reanim
Yumuşak Ergin G, Tıraş Çetin A, Ceylan A, Önal Altınkaya S, Çetin E.   +4 more
europepmc   +1 more source

Microglia‐Targeted Biomimetic Tetrahedral Framework Nucleic Acid Nanovesicles for Synergistic Treatment of Sepsis‐Associated Encephalopathy

Advanced Science, EarlyView.
Sepsis‐associated encephalopathy (SAE) lacks effective therapies. We developed ME@FDsi, a biomimetic nanodrug using a tetrahedral framework nucleic acid to deliver disulfiram and siTNFα. It crosses the blood‐brain barrier, targets M1 microglia, inhibits pyroptosis and inflammation, and scavenges ROS.
Huimin Shi, Qiuxia Gao, Wenying Wang, Bin Li, Yukun Chen, Zhijun Yao, Yujie Li, Junrui Li, Na Li, Gong Gu, Zhimin Hou, Mengyuan Yang, Ruilin Zhang, Hongju Yang, Yuhui Liao, Hongyi Lei   +15 more
wiley   +1 more source

Prognostic Value of Systemic Inflammation Markers (NLR and Haemoglobin) in Non-Small Cell Lung Cancer: Survival Analysis from a Real-World Single-Centre Cohort Study. [PDF]

Medicina (Kaunas)
Golban CM, Davidescu L, Alexandru A, Vlad S, Negru AG, Saftescu S, Ileana PC, Barbulescu CP, Negru SM.   +8 more
europepmc   +1 more source

The prevalence and impact of thrombocytopenia, anaemia and leucopenia on sustained virological response in patients receiving hepatitis C therapy: evidence from a large ‘real world’ cohort [PDF]

, 2016
Allen, Samuel, Barclay, Stephen T., Bramley, Peter, Dillon, John F., Fox, Raymond, Fraser, Andrew, Goldberg, David, Hayes, Peter, Hutchinson, Sharon, Innes, Hamish, Kennedy, Nicholas, Mills, Peter R., Wang, Huan   +12 more
core   +1 more source

Cross‐Modal Denoising and Integration of Spatial Multi‐Omics Data with CANDIES

Advanced Science, EarlyView.
In this paper, we introduce CANDIES, which leverages a conditional diffusion model and contrastive learning to effectively denoise and integrate spatial multi‐omics data. We conduct extensive evaluations on diverse synthetic and real datasets, CANDIES shows superior performance on various downstream tasks, including denoising, spatial domain ...
Ye Liu, Wanpeng Zou, Yuekai Li, Jiayi Wang, Mingxuan Cai, Hongmin Cai   +5 more
wiley   +1 more source

Improving the Algorithm: The Inclusion of a Socioeconomic Status Measure in Predicting Type 2 Diabetes Development in Youth With Prediabetes. [PDF]

Diabetes Care
Jang S, Wang Y, Ma S, Hsia DS, Cossen K, Haynes D, Bensignor MO.   +6 more
europepmc   +1 more source

Haemoglobin and Evolution [PDF]

BMJ, 1965
openaire   +2 more sources

Tetrahedral DNA Nanostructure‐Based Biomimetic Nanovesicles Attenuate Sepsis‐Associated ARDS by Suppressing Glycolysis via the BMAL1/PFKFB3 Axis

Advanced Science, EarlyView.
Upon inhalation, RM@TNT could persist long‐term in the diseased lungs, while undergoing disintegration to release TNT specifically within the ROS‐rich pathological microenvironments of SA‐ARDS. The released TNT was then precisely delivered to AMs via Tuftsin, where it released Nob intracellularly to activate BMAL1 expression, thus inhibiting AM ...
Yunlong Zhang, Bin Li, Zhijin Fan, Yan Yan, Fei Ma, Changting He, Shiping Liu, Mingliang Pan, Zhou Pan, Huijuan Wang, Xinting Fu, Jiamei Wang, Yue Jia, Qin Gu, Duo Jiang, Xueting Liu, Bohua Ren, Qinqin Wang, Yuehua Hei, Han Duan, Yanqiu Wu, Zihui Wei, Liying Zhan, Yuhui Liao   +23 more
wiley   +1 more source

Fructosamine and HbA1c for Monitoring Diabetes in Pregnancy: <i>Complementary or competing?</i> [PDF]

Sultan Qaboos Univ Med J
Htira Y, Jemai C, Fennira E, Hadj Ali Z, Lajili O, Hedfi I, Bettaieb J, Ben Mami F.   +7 more
europepmc   +1 more source

Integrating Radiomics and Computational Pathology to Predict Early Recurrence of Pancreatic Ductal Adenocarcinoma and Uncover Its Biological Basis in Tumor Microenvironment

Advanced Science, EarlyView.
Accurate prediction of early recurrence in pancreatic ductal adenocarcinoma is vital for optimizing treatment. A novel, integrated radiomics‐pathology machine learning model successfully forecasts recurrence risks by analyzing preoperative CT images and computational pathology.
Sihang Cheng, Fuze Cong, Shenbo Zhang, Rui Lv, Wenjia Zhang, Xinyi Ke, Juncheng Wu, Zhonghe Zhao, Kui Zhao, Di Dong, Ruofan Zhang, Zhengyu Jin, Max Seidensticker, Zhiwei Wang, Huanwen Wu, Xianlin Han, Nan Hong, Huadan Xue   +17 more
wiley   +1 more source