Results 241 to 250 of about 48,230 (310)

Higher Doses of Eculizumab may be Beneficial in Paroxysmal Nocturnal Haemoglobinuria in Pregnancy. [PDF]

Eur J Case Rep Intern Med
Patel HV, Stone S, Laird MC, Motiani V, Haque A, Tokala H, Amaraneni A.   +6 more
europepmc   +1 more source

Tackling cancer stemness with nanotechnology in the era of precision medicine

BMEMat, EarlyView.
Precise customization of nanoparticles (NPs) enables active targeting of cancer stem cells (CSCs), thereby improving drug delivery and therapeutic efficacy. NP‐based probing enhances CSC detection through imaging and liquid biopsy, whereas diverse therapeutic payloads improve therapeutic outcomes.
Shaolei Guo, Shun Yao, Lihui Meng, Chunyuan Chen, Yuechu Lucinda Lu, Rong Lu, Kashif Rafiq Zahid, Umar Raza, Qingzhi Wu, Wenli Chen   +9 more
wiley   +1 more source

Functional Evaluation, Antioxidant, Antimicrobial, Antibiofilm, and Haemolytic Capacity of <i>Calathea lutea</i> (Bijao) and <i>Calathea inocephala</i> (Shutupipanga) Leaves. [PDF]

Antioxidants (Basel)
Coyago-Cruz E, Mayorga-Ramos A, Méndez G, Alpusig-Guanoluisa L, Rivera-Rueda F, Zúñiga-Miranda J, Barba-Ostria C, Heredia-Moya J.   +7 more
europepmc   +1 more source

Sequential catalytic nanosystem of carbon dots and uricase integrated with polydopamine for therapy of gouty wound ulceration

BMEMat, EarlyView.
Sequential dual‐catalytic treatment of the gout wound ulceration process by CDs‐Uri@PDA. (a) Synthesis steps and morphology of CDs‐Uri@PDA. (b) Sequential treatment process and mechanism of CDs‐Uri@PDA for gout wound ulceration according to (i) uric acid reduction, (ii) antibacterial activity, and (iii) anti‐inflammatory effects.
Yonglan Yang, Yang Yang, Pengpeng Ma, Ruiqi Zhu, Xia Pan, Shaoling Zheng, Bo Chen, Yanli Jin, Youcong Gong, Jie Liu, Tianwang Li, Xu Chen   +11 more
wiley   +1 more source

G6PD deficiency in Indonesia: a systematic review and update of prevalence and variant maps in the context of malaria elimination. [PDF]

Lancet Reg Health West Pac
Sadhewa A, Panggalo LV, Nanine I, Fadilah I, Hutagalung J, Kenangalem E, Limardi PC, Malik SG, Noviyanti R, Pasaribu AP, Poespoprodjo JR, Prameswari HD, Price RN, Puspadewi RT, Setiadi W, Trianty L, Sudoyo H, Sutanto I, Syafruddin D, Kevin Baird J, Ley B, Elyazar IRF, Satyagraha AW.   +22 more
europepmc   +1 more source

Scalable desolvation synthesis, storage stability, and comprehensive biophysical characterization of human hemoglobin nanoparticles as a potential hemoglobin‐based oxygen carrier

Biotechnology Progress, EarlyView.
This work describes the development of human hemoglobin nanoparticles using an anti‐solvent precipitation synthesis method as a potential next generation hemoglobin‐based oxygen carrier. The hemoglobin nanoparticles are uniform in size and shape, hemocompatible, stable at various storage conditions, and demonstrate a scalable synthesis technique ...
Alisyn Greenfield, Andre F. Palmer
wiley   +1 more source

Tocilizumab provides a potential therapeutic option for the management of hyperhaemolysis syndrome in sickle cell disease: A case series and brief narrative overview of the literature. [PDF]

Transfus Med
Wolf S, Singh B, Zaidi A, Greaves P, Oyesanya F, Bennett S, Kaya B, Barroso F, Telfer P.   +8 more
europepmc   +1 more source

Around and Through: Successful Mitral Paravalvular Leakage Closure Using Both Anterograde and Retrograde Approaches

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Paravalvular leak (PVL) is a recognized complication after surgical mitral valve replacement and may cause heart failure, pulmonary hypertension, or hemolysis when moderate or severe. Although redo surgery is the definitive treatment, it carries substantial risk in elderly patients or those with multiple prior cardiac surgeries.
Marco Garaventa, Luca Nai Fovino, Tommaso Fabris, Giuseppe Tarantini   +3 more
wiley   +1 more source

Severe renal haemosiderosis in a patient with untreated paroxysmal nocturnal haemoglobinuria: a case report. [PDF]

BMC Nephrol
Goh ZZ, Tang K, Chau K, Viswanathan S.
europepmc   +1 more source

Repurposing Drugs for Malaria through a Human Dose Prediction: A Case Study with Berzosertib

Clinical Pharmacology &Therapeutics, EarlyView.
Repurposing drugs whose clinical safety has been established offers a valuable approach to reduce the cost and time associated with the development of new drugs for malaria. Here, we investigate the potential to repurpose the anticancer kinase inhibitor berzosertib for the treatment of malaria, by assessing whether a predicted efficacious human dose ...
Devasha Redhi, Mwila Mulubwa, Mmakwena M. Mmonwa, Mathew Njoroge, Liezl Krugmann, Kelly Chibale   +5 more
wiley   +1 more source