Results 111 to 120 of about 20,794 (210)

Single Cell Analysis Reveals the Presence of Novel Intermediate Cells in Both Mice and Patients With Severe MASLD

The FASEB Journal, Volume 40, Issue 6, 31 March 2026.
Schematic overview of the experimental workflow combining single‐cell RNA sequencing and spatial proteomics in a murine model of MASLD. Tissues were isolated, dissociated, and processed for single‐cell transcriptomic profiling to identify distinct cellular clusters and define cell‐type–specific gene expression signatures. Computational analysis enabled
Marica Meroni, Paride Pelucchi, Erika Paolini, Miriam Longo, Ada Sula, Michele Battistin, Alice Chiodi, Deborah Mattinzoli, Masami Ikehata, Elena Trombetta, Daniele Dondossola, Alessandra Mezzelani, Gianluca Martino Tartaglia, Giuseppe Castellano, Anna Ludovica Fracanzani, Flora Peyvandi, Stefano Gatti, Ettore Mosca, Paola Dongiovanni   +18 more
wiley   +1 more source

CBP/β‐Catenin Signaling in Hepatocytes Plays Pivotal Roles in MMP‐7‐Mediated Liver Fibrosis in a Metabolic Dysfunction‐Associated Steatohepatitis Mouse Model

The FASEB Journal, Volume 40, Issue 6, 31 March 2026.
CDAHFD‐induced hepatic steatosis stimulates CBP/β‐catenin signaling in hepatocytes, leading to increased production of the downstream effector MMP‐7. Hepatocyte‐derived MMP‐7 contributes to fibrogenic responses and is associated with the progression of liver fibrosis.
Jun Imamura, Masamichi Kimura, Yumi Otoyama, Koji Nishikawa, Michinori Kohara, Kiminori Kimura   +5 more
wiley   +1 more source

Dual‐Functional Polyphosphoesters for Gene Delivery: Synergistic Effects of Guanidinium and Hydrophobic Side Chains in Degradable Polymers

Advanced Healthcare Materials, Volume 15, Issue 9, 6 March 2026.
This study presents guanidinium‐ and indole‐functionalized polyphosphoesters as degradable, non‐viral gene delivery vectors. Through precise tuning of charge density and hydrophobicity, these polymers form stable polyplexes with low toxicity. Remarkably, minor structural changes yield up to 200‐fold differences in transfection efficiency, highlighting ...
Markus Kötzsche, Andreas Dzierza, Jan Egger, Timo Rheinberger, Christin Weilandt, Frederik R. Wurm, Ivo Nischang, Dagmar Fischer, Kalina Peneva   +8 more
wiley   +1 more source

HAEMATURIA IN PATIENTS WITH HAEMOPHILIA

Zdravniški Vestnik, 2008
BACKGROUND A review article intends to discover a cause, frequency, treatment and complications ofhaematuria in patients with haemophilia. METHODS A review of PubMed (1969–2007) for key words haemophilia, haematuria and renaldisease. RESULTS Four studies
Majda Benedik Dolničar
doaj  

Redefining the role of the transfusion medicine physician in the era of advanced cellular therapies

Transfusion, EarlyView.
Eric A. Gehrie, Kevin J. Land
wiley   +1 more source

Factor XIII Deficiency: A Silent Bleeder Behind a Normal Coagulation Profile

Clinical Case Reports, Volume 14, Issue 3, March 2026.
ABSTRACT Factor XIII deficiency is a rare cause of bleeding disorder. An 8‐month‐old male infant presented with persistent bleeding from a minor lip cut injury, which was sustained 2 days prior. The bleeding did not stop despite local hemostatic measures.
Ramesh Yadav, Madhav Raj Karki, Dikshya Pokhrel, Aron Neupane, Kshitiz Parajuli, Hem Sagar Rimal   +5 more
wiley   +1 more source

Management of neonatal massive hemorrhage: A narrative review

Transfusion, EarlyView.
Cheryl S. L. Chooi, Mary Claire Simmonds, Laura Fisher, Tara Crawford, Michael J. Stark, Scott Morris, Marcus Brecht, Fiona Taverner   +7 more
wiley   +1 more source

Asundexian Versus Apixaban in Patients With Atrial Fibrillation

Health Science Reports, Volume 9, Issue 3, March 2026.
ABSTRACT Background Anticoagulation therapy is central to the prevention of thromboembolic disorders but is limited by bleeding complications associated with traditional agents such as warfarin and direct oral anticoagulants (DOACs). Factor XIa inhibition has emerged as a novel strategy aimed at reducing thrombotic risk while preserving hemostasis ...
Zara Saeed, Syeda Ariba Zehra, Sumyya Tariq, Rocio Pun Zumaran, Mounika Kotte, Zeeshan Hameed, Neeraj Joshi, Pushpa Kumari, Kanta Kumari, Awais Habib, Fawad Talat, Osama Taj, Jahanzeb Malik, Abida Perveen   +13 more
wiley   +1 more source

Patients' Associations as Co‐Creators of Knowledge: Insights From a Community‐Based Participatory Research Study (ProSafe Project)

Health Science Reports, Volume 9, Issue 3, March 2026.
ABSTRACT Background and Aims Patient and public involvement and engagement (PPIE) in research is crucial for producing knowledge that is meaningful to the participating community. Sharing PPIE principles into practical tools and strategies enriches the development of participatory research methodologies.
Francesca Moretti, Silvia Colpo, Sara Montresor, Daniela Facchinello, Raffaella Robello, Mariangela Mazzi, Stefano Tardivo, Lisa Stagi, Luisa De Stefano, Andrea Zotti, Luigi Ambroso, Cristina Destro, Salvo Leone, Davide Petruzzelli, Ugo Moretti, Michela Rimondini   +15 more
wiley   +1 more source

PB2652: EVALUATION OF 6 CASES WITH FXIII DEFICIENCY: SINGLE CENTRE EXPERIENCE

HemaSphere, 2023
Fahri Sahin, Denis Bozer, Zuhal Demirci, Guray Saydam   +3 more
doaj   +1 more source