Results 161 to 170 of about 32,062 (289)

Long-term impact of COVID-19 on haemophilia: a multicenter study in Southwest China. [PDF]

BMC Infect Dis
Cao C, Chen S, Liu Y, Tan X, Zhu J, Deng J, Ma H, Li T, Zhang Q, Gan X, Wu X.   +10 more
europepmc   +1 more source

Perioperative Management in Persons With Haemophilia on Rebalancing Therapies: A Narrative Review

Haemophilia, EarlyView.
ABSTRACT Introduction Perioperative management in haemophilia often requires on‐demand use of clotting factor concentrates (CFC) and/or bypassing agents. Rebalancing agents (fitusiran, concizumab, marstacimab) offer a novel approach to prophylaxis by modulating endogenous anticoagulant pathways to restore haemostatic balance.
Amanda M. Henderson, Roy Khalife, Kelsey Uminski   +2 more
wiley   +1 more source

Variables Affecting Periprocedural Haemostatic Response in Patients With Haemophilia: Real-World Retrospective Study. [PDF]

EJHaem
Sanchez Salas JA, Soler Espejo E, García Candel F, Roldán Schilling V.   +3 more
europepmc   +1 more source

100 Years of von Willebrand Disease (VWD): Comparison of Historical and Contemporary von Willebrand Factor (VWF) Activity Assays in the Laboratory Identification of VWD

Haemophilia, EarlyView.
Abstract Introduction von Willebrand disease (VWD) is a prevalent bleeding disorder resulting from deficiencies and/or defects in von Willebrand factor (VWF). Accurately diagnosing VWD, particularly distinguishing between qualitative defects (types 2A, 2B, 2 M, and 2N) and quantitative defects (types 1 and 3), poses challenges that have significant ...
Emmanuel J. Favaloro, Sandya Arunachalam, Mahzuza Salwa, Ronny Vong, Leonardo Pasalic   +4 more
wiley   +1 more source

In a nutshell: Explaining joint and muscle bleeding in individuals with haemophilia A and B. [PDF]

Br J Haematol
Lau BK, Srivatsa S, Mackman N.
europepmc   +1 more source

Efficacy of Air‐Polishing in Managing Biofilm Formation in Patients Wearing Fixed Orthodontic Appliances: A Single‐Blind, Split‐Mouth, Randomised Controlled Trial

International Journal of Dental Hygiene, EarlyView.
ABSTRACT Objectives To investigate the efficacy of air‐polishing in managing biofilm formation in patients wearing fixed orthodontic appliances. Methods This pilot study was designed as a single‐blind split‐mouth randomised controlled study. Twenty patients undergoing fixed orthodontic treatment were enrolled.
James Millar, Tianyou Wu, Richard D. Cannon, Mauro Farella, Li Mei   +4 more
wiley   +1 more source

Advanced Molecular Analysis in Hemophilia A in a Single Step: Next Generation Sequencing (NGS) and Copy Number Variation (CNV) Analysis

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Background Hemophilia A, an X‐linked bleeding disorder caused by pathogenic variants in the F8 gene, requires precise genetic diagnosis for optimal management. Conventional stepwise sequence and copy number variation (CNV) analyses are time‐consuming and may leave some cases unresolved.
Enise Avci Durmusalioglu, Esra Isik, Basak Durmus Ozen, Mehmet Mert Topaloglu, Nihal Karadas, Kaan Kavakli, Melike Sezgin Evim, Tolga Aslan, Erşen Kavak, Adalet Meral Gunes, Funda Tayfun Kupesiz, Alphan Kupesiz, Fahri Sahin, Tahir Atik   +13 more
wiley   +1 more source

Perceived Barriers to Healthcare Access Among Paediatric Patients With Haemophilia in Cambodia: A Cross-Sectional Survey. [PDF]

Haemophilia
Sophâl C, Sivmeng H, Kimsreng L, Ponndara I.   +3 more
europepmc   +1 more source

How I Investigate Bleeding Disorders of Unknown Cause: Current Diagnostic Pathways and Gaps in Laboratory Investigation

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Bleeding disorder of unknown cause (BDUC) constitutes the largest group of patients presenting with a mild‐to‐moderate bleeding tendency in tertiary care settings. Their clinical bleeding phenotype is characterized by mucocutaneous bleeding, as well as bleeding following surgical challenges or childbirth, and is associated with impaired health‐
Dino Mehic, Faris Karaselimovic, Tim Dreier, Johanna Gebhart   +3 more
wiley   +1 more source

An Ex Vivo Pharmacodynamic Study of KN057, a Tissue Factor Pathway Inhibitor Neutralizing Antibody, in Plasma Samples From Patients With Haemophilia or VWD3. [PDF]

Haemophilia
Ju M, Xue F, Sun W, Li F, Xu T, Yang R.
europepmc   +1 more source