Results 1 to 10 of about 235 (117)
Impact of Functional Disability on Quality of Life in Patients with Haemophilia: An Observational Study [PDF]
Journal of Clinical and Diagnostic Research, 2021 Introduction: Haemophilia is a disease characterised by multiple episodes of spontaneous as well as traumatic bleeding leading to joint pains, joint damage.
Ashish Kavi +3 more
doaj +1 more source
Gene Therapy in Hemophilia: A Transformational Patient Experience
Journal of Patient Experience, 2023 Hemophilia is a bleeding disorder caused by a single absent/defective gene and characterized by a lack of functional clotting factors. People with hemophilia may experience joint damage, pain, and psychological impairments, all of which could contribute ...
Enayet Rasul +7 more
doaj +1 more source
South African Family Practice, 2022 Background: Haemophilia A and B are X-linked recessive bleeding disorders resulting from a deficiency of factors VIII and IX, respectively. Early diagnosis and a comprehensive approach to management is mandatory.
Lethukuthula Mafisa +2 more
doaj +1 more source
Utilization evaluation of factor concentration and frequencyof bleeds among patients with haemophilia "A" and haemophilia "B" in northwest Iran [PDF]
Journal of Analytical Research in Clinical Medicine, 2013 Background Haemophilia A and B are X-linked bleeding disorders which result in decreased blood levels of coagulants. According to some studies, Hemophilia Severity Score (HSS) is higher in severe Haemophilia A(HA) than in severe Haemophilia B(HB ...
Roya Dolatkhah +5 more
doaj +1 more source
International consensus recommendations on the management of people with haemophilia B
Therapeutic Advances in Hematology, 2022 Haemophilia B is a rare X-linked genetic deficiency of coagulation factor IX (FIX) that, if untreated, can cause recurrent and disabling bleeding, potentially leading to severe arthropathy and/or life-threatening haemorrhage.
Daniel P. Hart +14 more
doaj +1 more source
Molecular Profiling of FIX (FACTOR 9) Gene of Hemophilia B in Karnataka
BLDE University Journal of Health Sciences, 2020 Introduction: Haemophilia is one of the “Bleeder Disorder” that causes abnormal bleeding or poor blood clotting. It occurs due to the defect in the clotting factors even in their functions and in some cases structures are altered.
Sujayendra Kulkarni +6 more
doaj +1 more source
Orphanet Journal of Rare Diseases, 2021 Background Real-world studies of the burden of severe haemophilia B in the context of recent therapeutic advances such as extended half-life (EHL) factor IX (FIX) products are limited.
Tom Burke +5 more
doaj +1 more source
Global measurement of coagulation in plasma from normal and haemophilia dogs using a novel modified thrombin generation test - Demonstrated in vitro and ex vivo. [PDF]
PLoS ONE, 2017 Canine models of severe haemophilia resemble their human equivalents both regarding clinical bleeding phenotype and response to treatment. Therefore pre-clinical studies in haemophilia dogs have allowed researchers to make valuable translational ...
Daniel Elenius Madsen +4 more
doaj +1 more source
Medicina, 2021 We present the case of a 70-year-old man with a history of haemophilia B, who presented to our hospital with a non-ST-elevation myocardial infarction.
Konstantinos C. Theodoropoulos +6 more
doaj +1 more source
BMJ Open, 2021 Introduction Two meta-analyses showed lower bone mineral density (BMD) in patients with haemophilia (haemophilia type and severity were often not specified) compared with healthy controls.
Brigitte Tardy‐Poncet +7 more
doaj +1 more source