Results 51 to 60 of about 32,062 (289)

Human biomarker navigator

iMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source

Time‐ and Temperature‐Dependent Response of Acquired FV Inhibitors: Implications for Laboratory Diagnosis and Clinical Management

Journal of Clinical Laboratory Analysis, EarlyView.
This in vitro workflow illustrates the time‐and temperature‐dependent behavior of acquired FV inhibitors. Patient plasma was centrifuged and serially diluted, followed by parallel incubation at room temperature and 37°C. Serial measurements of APTT mixing test and residual FV activity were recorded across incubation time points to monitor inhibitor ...
Lihua Zhang, Mingjie Li, Zhiqiang Xie, Junxiang Yao, Yingping Cao, Lihui Chen, Meihua Wang   +6 more
wiley   +1 more source

Distribution and predictors of haemophilia-related costs in the United Kingdom: analysis of the CHESS I and CHESS II burden of illness studies

BMC Health Services Research
Background Few studies have evaluated direct medical or societal costs of haemophilia in the United Kingdom (UK), and how patient characteristics impact future costs is uncertain.
Ione Woollacott, Amit Chhabra, Tom Burke, Jack Brownrigg, Lucy Richardson, Enrico Ferri Grazzi, Jamie O’Hara, Josie Godfrey, Michael Laffan   +8 more
doaj   +1 more source

Haemophilia [PDF]

, 2019
Haemophilia A and haemophilia B are inherited bleeding disorders caused by deficiencies in blood clotting factor proteins. This chapter gives an overview of evidence about psychological aspects of haemophilia, including inheritance, adherence to ...
Elander, James
core  

Understanding the Concept of Self‐Performed Ultrasound: A Scoping Review

Journal of Ultrasound in Medicine, EarlyView.
Self‐performed ultrasound is an emerging technology that facilitates adept self‐scans in untrained hands. Inspired by self‐performed imaging in space for more prompt diagnosis and therapy, it has the potential to accurately monitor chronic conditions remotely. However, the lack of supervision and physical restraints can hinder its usability.
Vy Do, Anson Chau, Elio Arruzza, Nayana Parange   +3 more
wiley   +1 more source

Health-related quality of life of moderate and severe haemophilia patients: Results of the haemophilia-specific quality of life index in Korea.

PLoS ONE, 2020
The assessment of health-related quality of life (HRQoL) as a patient-reported outcome provides information about the patients' general well-being as well as the effects of the disease and its treatment.
Hee Jo Baek, Young Shil Park, Ki Young Yoo, Jin-Hye Cha, Young-Joo Kim, Kun Soo Lee   +5 more
doaj   +1 more source

Gene therapy in haemophilia: literature review and regional perspectives for Turkey

Therapeutic Advances in Hematology, 2022
Haemophilia is an X-linked lifelong congenital bleeding disorder that is caused by insufficient levels of factor VIII (FVIII; haemophilia A) or factor IX (FIX; haemophilia B) and characterized by spontaneous and trauma-related bleeding episodes.
Kaan Kavaklı, Bülent Antmen, Vahap Okan, Fahri Şahin, Selin Aytaç, Can Balkan, Ergül Berber, Zühre Kaya, Alphan Küpesiz, Bülent Zülfikar   +9 more
doaj   +1 more source

Patients with obesity have a higher risk of periprosthetic joint infection and more frequent polymicrobial infections after knee arthroplasty: A nationwide register‐based study from Denmark

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose To compare the 2‐year incidence of (1) revision due to periprosthetic joint infection (PJI) and (2) all‐cause revision after primary knee arthroplasty (KA) in patients with/without obesity and to compare the microbial profiles in early (≤ 90 days) and late (91–730 days) PJI.
Saber M. Aljuboori, Espen Jimenez‐Solem, Henrik Calum, Robin Christensen, Søren Overgaard   +4 more
wiley   +1 more source

Pain management in patients with haemophilia : a European survey

, 2012
Summary. There are no evidence-based guidelines on pain management in people with haemophilia (PWH), who may suffer acute, disabling pain from haemarthroses and chronic arthropathic pain.
R. Klamroth, M. Richards, R. Pérez Garrido, M. Carvalho, the European Haemophilia Therapy Standardization Board, K. Holstein, A. Gringeri   +6 more
core   +1 more source

Specific functional knee phenotypes are associated with increased osteoarthritis progression: A ≥10‐year longitudinal study

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose To evaluate osteoarthritis (OA) progression across functional knee phenotypes (FKPs) over a follow‐up period of ≥10 years. Methods This retrospective longitudinal study included 388 patients (764 knees) with healthy knees or early OA (Kellgren–Lawrence grade ≤1) at baseline and a minimum follow‐up of 10 years.
Sang Jun Song, Hyo Beom Lee, Cheol Hee Park   +2 more
wiley   +1 more source