Results 221 to 230 of about 21,171,014 (388)

Real‐World Effectiveness and Safety of Damoctocog Alfa Pegol in Severe and Nonsevere Patients With Hemophilia A From the Prospective, Multinational, Ongoing HEM‐POWR Study

European Journal of Haematology, Volume 116, Issue 2, Page 148-159, February 2026.
ABSTRACT Objectives To assess the effectiveness and safety of damoctocog alfa pegol in patients with severe and nonsevere hemophilia A in the fifth interim analysis of the ongoing HEM‐POWR study. Methods HEM‐POWR (NCT03932201) is a multinational, Phase 4, prospective observational study.
Mark T. Reding, María Teresa Alvarez Román, Giancarlo Castaman, Maissaa Janbain, Tadashi Matsushita, Karina Meijer, Kathrin Schmidt, Johannes Oldenburg   +7 more
wiley   +1 more source

Posterior fossa extradural haematoma with cerebral venous sinus thrombosis precipitates haemophilia a diagnosis: a paediatric case report and literature review. [PDF]

Childs Nerv Syst
Akhbari M, Owen W, Honeyman SI, Badle S, Calisto A.   +4 more
europepmc   +1 more source

Mental, emotional and social dimensions of quality of life and their relationship with physical and functional status in adults with haemophilia [PDF]

Marta Aguilar‐Rodríguez, Sofía Pérez‐Alenda, Juan J. Carrasco, Juan Eduardo Megías‐Vericat, Santiago Bonanad, Felipe Querol, Ana Chimeno‐Hernández   +6 more
openalex   +1 more source

Mutation analysis in the F8 gene in 485 families with haemophilia A and prenatal diagnosis in China [PDF]

, 2020
Yin Feng, Qianqian Li, Panlai Shi, Ning Liu, Xiangdong Kong, Ruixia Guo   +5 more
openalex   +1 more source

Facts and Misfacts on D‐Dimer Testing. Consensus Guidance From the Italian Society on Thrombosis and Hemostasis (SISET)

American Journal of Hematology, Volume 101, Issue 1, Page 97-109, January 2026.
ABSTRACT D‐dimer defines degradation products derived from the proteolysis mediated by plasmin on cross‐linked fibrin. The evidence‐based use of D‐dimer in some conditions has been consolidated. Currently, however, there is an entrenched prescription of D‐dimer testing to screen otherwise healthy subjects that may induce prescribing physicians to start
Armando Tripodi, Walter Ageno, Luca Barcella, Antonio Coppola, Marcello Di Nisio, Massimo Franchini, Monia Marchetti, Rossella Marcucci, Marco Marietta, Pasquale Pignatelli, Domenico Prisco, Valerio De Stefano   +11 more
wiley   +1 more source

A Story Worth Telling: The Evolution of Haemophilia Care in Canada. [PDF]

Haemophilia
Uminski K, Lee A.
europepmc   +1 more source

Proteomic and Ubiquitinated Proteome Insights Into ER Stress Responses in Chinese Hamster Ovary Cells Under Mild Hypothermic Conditions

Biotechnology and Bioengineering, Volume 123, Issue 1, Page 5-25, January 2026.
Proteomic analysis of CHO cells under mild hypothermia (31°C) reveals ER stress responses, ubiquitination dynamics, and adaptive mechanisms. Magnetic immuno‐affinity enrichment and mass spectrometry highlight protein regulation differences in non‐producer versus producer cells, offering insights for optimising biopharmaceutical production of IgG1 and ...
David Ryan, Christiana‐Kondylo Sideri, Michael Henry, Selvaprakash Karuppuchamy, Esen Efeoglu, Paula Meleady   +5 more
wiley   +1 more source

NuPOWER (Nuwiq for Perioperative management Of patients With haemophilia A on Emicizumab Regular prophylaxis): protocol for an open-label, single-arm, multicentre study. [PDF]

BMJ Open
Srivastava A, Kanny A, Langer F, Kubicek-Hofmann C, Álvarez Román MT, Núñez Vázquez R, Boban A, Dejanova-Ilijevska V, Miljić P, Garcia J, Halimeh S, Drillaud N, Valentin JB, Mancuso ME, Castaman G, Santoro RC, Lehtinen AE, Abraham A, Hashimoto M, Knaub S.   +19 more
europepmc   +1 more source

Downstream Process Intensification for AAV Purification by Affinity Chromatography Using Single Pass Tangential Flow Filtration

Biotechnology and Bioengineering, Volume 123, Issue 1, Page 174-185, January 2026.
ABSTRACT To enable adeno‐associated viral vectors (AAV) to achieve their maximum potential, next‐generation manufacturing processes must be developed to make gene therapies more affordable and accessible. This study focused on the design of two different intensified AAV downstream manufacturing processes at bench and pilot scale.
Akshay S. Chaubal, Ronny Horax, Christopher J. Yehl, S. Ranil Wickramasinghe, Xianghong Qian, Lu Wang, Andrew L. Zydney   +6 more
wiley   +1 more source

Real-World Experience with Eptacog Beta for On-Label and Off-Label Indications: The Spanish Experience. [PDF]

Pharmaceuticals (Basel)
Martin de Bustamante JM, Rivas-Pollmar MI, Acedo N, Butta N, Jimenez-Yuste V, Álvarez-Román MT.   +5 more
europepmc   +1 more source