Results 111 to 120 of about 18,669 (233)

A Common Language for the Multidisciplinary Team: Point‐of‐Care Musculoskeletal Ultrasound in Modern Haemophilia Care

Haemophilia, EarlyView.
ABSTRACT The evolving haemophilia care landscape has evolved with personalised prophylaxis, new coagulation factor molecules, non‐replacement therapies, and gene therapy, leading to significantly reduced bleeding frequency and haemophilic arthropathy burden.
Hortensia De la Corte‐Rodriguez, María Teresa Álvarez‐Román, Mauro Davoli, Magnus Aspdahl, Christina Burgess, Karin Fijinvandraat, Roberta Gualtierotti, Cedric Hermans, Marko Marinić, Carlo Martinoli, Wolfgang Miesbach, Gianluigi Pasta, Michael Sigl‐Kraetzig, David Stephensen, Malin Svennefalk, Víctor Jiménez‐Yuste, the E.A.H.A.D. Joint Health Group   +16 more
wiley   +1 more source

Cost analysis of extended half-life recombinant factor IX products in the treatment of haemophilia B in Italy: an update. [PDF]

Glob Reg Health Technol Assess, 2022
Aiello A, Mancuso ME, Leone S, Rossi L, Cioni L, Teruzzi C.   +5 more
europepmc   +1 more source

Understanding Contact Risks of Pediatric Physical Activity: Video Analysis to Inform Decisions for Children at Risk of Bleeding Injuries

Haemophilia, EarlyView.
ABSTRACT Introduction Physical activity guidelines for children with inherited or acquired bleeding disorders are largely based on expert opinion rather than objective measures of injury exposure, making evidence‐based participation recommendations challenging.
Lauren Backstein, Ria Patel, Mona Elmikaty, Brooklyn Westlake, Sarah Sbeiti, Leonardo R. Brandão, Robert Klaassen, Allison Clouthier, Chris Joslin, Ryan Graham, Patricia E. Longmuir   +10 more
wiley   +1 more source

Safety of Damoctocog Alfa Pegol in Patients With Severe Haemophilia A Aged 7 to <12 Years of Age: Pooled Data From PROTECT VIII Kids and Alfa‐PROTECT

Haemophilia, EarlyView.
Margareth C. Ozelo, Anthony K. C. Chan, Matteo Luciani, Monika Maas Enriquez, Claudia Tueckmantel, Maria Elisa Mancuso   +5 more
wiley   +1 more source

Population Pharmacokinetics of Plasma‑Derived Factor X Using Clotting and Chromogenic Assays: A WAPPS‑Hemo Model

Haemophilia, EarlyView.
ABSTRACT Background Hereditary factor X (FX) deficiency is a rare autosomal recessive bleeding disorder for which individualized pharmacokinetic (PK) assessment can support optimized prophylactic management. The WAPPS‐Hemo platform enables population pharmacokinetic (PopPK) individualized PK predictions based on sparse sampling.
Dagmar M. Hajducek, Pierre Chelle, Manuela Scarpellini, Andrea Edginton, Alfonso Iorio   +4 more
wiley   +1 more source

Perioperative Management in Persons With Haemophilia on Rebalancing Therapies: A Narrative Review

Haemophilia, EarlyView.
ABSTRACT Introduction Perioperative management in haemophilia often requires on‐demand use of clotting factor concentrates (CFC) and/or bypassing agents. Rebalancing agents (fitusiran, concizumab, marstacimab) offer a novel approach to prophylaxis by modulating endogenous anticoagulant pathways to restore haemostatic balance.
Amanda M. Henderson, Roy Khalife, Kelsey Uminski   +2 more
wiley   +1 more source

100 Years of von Willebrand Disease (VWD): Comparison of Historical and Contemporary von Willebrand Factor (VWF) Activity Assays in the Laboratory Identification of VWD

Haemophilia, EarlyView.
Abstract Introduction von Willebrand disease (VWD) is a prevalent bleeding disorder resulting from deficiencies and/or defects in von Willebrand factor (VWF). Accurately diagnosing VWD, particularly distinguishing between qualitative defects (types 2A, 2B, 2 M, and 2N) and quantitative defects (types 1 and 3), poses challenges that have significant ...
Emmanuel J. Favaloro, Sandya Arunachalam, Mahzuza Salwa, Ronny Vong, Leonardo Pasalic   +4 more
wiley   +1 more source

Unexpected haemophilia despite pre‐natal testing – a combined haemophilia A and haemophilia B family [PDF]

British Journal of Haematology, 2017
Noémi B. A. Roy, Nicola Curry, David Keeling   +2 more
openaire   +2 more sources

Efficacy of Air‐Polishing in Managing Biofilm Formation in Patients Wearing Fixed Orthodontic Appliances: A Single‐Blind, Split‐Mouth, Randomised Controlled Trial

International Journal of Dental Hygiene, EarlyView.
ABSTRACT Objectives To investigate the efficacy of air‐polishing in managing biofilm formation in patients wearing fixed orthodontic appliances. Methods This pilot study was designed as a single‐blind split‐mouth randomised controlled study. Twenty patients undergoing fixed orthodontic treatment were enrolled.
James Millar, Tianyou Wu, Richard D. Cannon, Mauro Farella, Li Mei   +4 more
wiley   +1 more source

Advanced Molecular Analysis in Hemophilia A in a Single Step: Next Generation Sequencing (NGS) and Copy Number Variation (CNV) Analysis

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Background Hemophilia A, an X‐linked bleeding disorder caused by pathogenic variants in the F8 gene, requires precise genetic diagnosis for optimal management. Conventional stepwise sequence and copy number variation (CNV) analyses are time‐consuming and may leave some cases unresolved.
Enise Avci Durmusalioglu, Esra Isik, Basak Durmus Ozen, Mehmet Mert Topaloglu, Nihal Karadas, Kaan Kavakli, Melike Sezgin Evim, Tolga Aslan, Erşen Kavak, Adalet Meral Gunes, Funda Tayfun Kupesiz, Alphan Kupesiz, Fahri Sahin, Tahir Atik   +13 more
wiley   +1 more source