Results 121 to 130 of about 18,669 (233)

How I Investigate Bleeding Disorders of Unknown Cause: Current Diagnostic Pathways and Gaps in Laboratory Investigation

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Bleeding disorder of unknown cause (BDUC) constitutes the largest group of patients presenting with a mild‐to‐moderate bleeding tendency in tertiary care settings. Their clinical bleeding phenotype is characterized by mucocutaneous bleeding, as well as bleeding following surgical challenges or childbirth, and is associated with impaired health‐
Dino Mehic, Faris Karaselimovic, Tim Dreier, Johanna Gebhart   +3 more
wiley   +1 more source

CS05 | Joint ultrasound follow-up in pediatric patients with haemophilia: a 12-year prospective single-center experience

Bleeding, Thrombosis and Vascular Biology
Introduction: Periodic monitoring of joints status in patients with haemophilia (PwH) is recommended to identify and prevent the arthropathies. Ultrasound (US) is able to detect and quantify markers of disease activity and degenerative damage.
doaj   +1 more source

Optimizing Perioperative Management of Haemophilia B With rFIX-FP: Pharmacokinetic Validation of the Hemoptidose Tool. [PDF]

Haemophilia
Delavenne X, Vollard C, Drillaud N, Castet S, Luyck N, Hénin E, Seve JD, Volot F, Tardy B, Désage S, Guillet B.   +10 more
europepmc   +1 more source

Testing for Non‐Severe Heritable Platelet Function Disorders

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Heritable platelet function disorders (HPFD) are a diverse group of bleeding disorders characterised by a primary qualitative defect in platelet function rather than platelet number. HPFD may be broadly categorised according to the severity of bleeding, with Glanzmann thrombasthenia and Bernard Soulier syndrome classically considered severe ...
Kate Burley, Naomi Cornish, Maria Molina Carretero, Sarah K. Westbury   +3 more
wiley   +1 more source

UK Experience of Children With Inhibitors in Severe Haemophilia B: A Report by the UKHCDO Paediatric Working Party. [PDF]

Haemophilia
Mathias M, Alamelu J, Bhatnagar N, Biss T, Grainger J, Green S, M AK, Motwani J, Payne J, Stokley S.   +9 more
europepmc   +1 more source

Optimal trough levels in haemophilia B: Raising expectations. [PDF]

Haemophilia, 2020
Walsh C, Coppens M, Escobar M, Wang M.
europepmc   +1 more source

Factors Associated With Challenging Behaviour in People With Severe‐Profound Intellectual Disabilities: A Systematic Review

Journal of Intellectual Disability Research, EarlyView.
ABSTRACT Background Individuals with severe to profound intellectual disability (ID) exhibit high support needs and significant communication impairments and may present with challenging behaviours such as aggression, self‐injury and stereotypies. These behaviours can cause distress, hinder healthcare access and delivery and impair quality of life for ...
I. D. C. van Balkom, J. Cooke, A. G. de Cuba, E. Burkitt‐Wright, C. Gaasterland, M. Burdeus‐Olavarrieta   +5 more
wiley   +1 more source

Perceptions and Recommendations Regarding Haemophilia B Gene Therapy: A Multistakeholder View From Patients, Caregivers and Healthcare Professionals. [PDF]

Haemophilia
Bhatt N, Anderson T, Bryndziar T, Fortner G, Fowlkes L, Khan H, Hodges JR, Reiss UM.   +7 more
europepmc   +1 more source

Plasma ADAMTS13 activity in healthy dogs and dogs with chronic enteropathy

Journal of Small Animal Practice, EarlyView.
Objectives A disintegrin and metalloproteinase with thrombospondin type 1 motif, member 13 is a von Willebrand factor cleaving enzyme that is associated with prothrombotic/hypercoagulable states in humans. In people, A disintegrin and metalloproteinase with thrombospondin type 1 motif, member 13 activity is reduced with inflammatory bowel disease ...
S. I. Barth, S. M. DeMonaco, B. J. Conner, P. B. S. Serpa, A. R. Wilkinson   +4 more
wiley   +1 more source

Haemophilia B: an illustrative review of current challenges and opportunities. [PDF]

Res Pract Thromb Haemost
Hermans C, Astermark J, Trakymienė SŠ, Jiménez-Yuste V.   +3 more
europepmc   +1 more source