Results 141 to 150 of about 18,669 (233)

Preclinical development of plant-based oral immune modulatory therapy for haemophilia B. [PDF]

Plant Biotechnol J, 2021
Srinivasan A, Herzog RW, Khan I, Sherman A, Bertolini T, Wynn T, Daniell H.   +6 more
europepmc   +1 more source

Treatment of Deep Vein Thrombosis in Congenital Factor VII Deficiency: A Case Report and Literature Review

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT Managing thrombosis in patients with bleeding disorders requires careful assessment of thromboembolic and bleeding risks, tailoring antithrombotic treatment in terms of type, dose, and duration, and considering the need for replacement therapy based on individual factor levels and bleeding history.
Synnøve Gjelsten Mortensen, Lars Erik Laugsand, Martin Syvertsen Mykland, Erik Magnus Berntsen, Tobias S. Slørdahl   +4 more
wiley   +1 more source

Long Term Follow Up of Hereditary Thrombotic Thrombocytopenic Purpura on Plasma Therapy for 9 Years: A Case Report

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT A 7.6‐year‐old boy with hTTP had fever‐induced hemorrhagic rash, MAHA, cerebral infarction, and renal impairment. After plasma therapy, symptoms were partially relieved; 9‐year follow‐up showed regular plasma transfusion was needed, with CKD Stage 3.
Dai Xiaomei, Chen Ruyue, Wu Shuang, Tang Hanyun, Lin Qiang, Li Xiaozhong   +5 more
wiley   +1 more source

Ddavp treatment in children with haemophilia b [PDF]

British Journal of Haematology, 2001
Kavakli, K, Aydinok, Y, Karapinar, D, Balkan, C   +3 more
openaire   +2 more sources

Real-World Unmet Needs of Patients With Haemophilia A and Haemophilia B With or Without Inhibitors: End-of-Study Results From the explorer6 Non-Interventional Study. [PDF]

Haemophilia
Wheeler AP, Abraham A, Barnes C, Brown Frandsen R, d'Oiron R, Eichler H, Hampton K, López-Jaime FJ, Lyu CJ, Tavares CMM, Nogami K, Sutton C, Windyga J, Zulfikar B, Castaman G.   +14 more
europepmc   +1 more source

How to Avoid Misdiagnosing Primary Spinal Epidural Abscess as Spinal Epidural Hematoma: A Case Report and Literature Review

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT Spinal epidural abscess (SEA) is an easily misdiagnosed disease. We report a case of primary SEA (PSEA) that was misdiagnosed as spinal epidural hematoma (SEH) and analyze the reasons. The misdiagnosis was confirmed intraoperatively. Comprehensive analysis is crucial for the diagnosis of PSEA and its differential diagnosis from SEH.
Sheng‐Wei Meng, Qian Liu, Yong‐Sheng Zhao   +2 more
wiley   +1 more source

Comparing Real-World Outcomes of Prophylaxis with Extended Half-life Factor IX (rIX-FP vs. rFIXFc and N9-GP) for Haemophilia B: An Analysis of Medical Chart Data from Germany. [PDF]

Adv Ther
Olivieri M, Yan S, Yang Y, Tomic R, Linhoff T, Zhang X, Drelich D, Jakobs N, Miesbach W.   +8 more
europepmc   +1 more source

High adherence to prophylaxis regimens in haemophilia B patients receiving rIX-FP: Evidence from clinical trials and real-world practice. [PDF]

Haemophilia, 2020
Mancuso ME, Oldenburg J, Boggio L, Kenet G, Chan A, Altisent C, Seifert W, Santagostino E.   +7 more
europepmc   +1 more source

Operationalizing Precision Medicine in Drug Development: Predictive Biomarkers, Companion Diagnostics, and Regulatory Pathways

Clinical Pharmacology &Therapeutics, Volume 120, Issue 4, Page 914-929, October 2026.
Precision medicine offers the opportunity to improve the benefit–risk profile of new therapies by prospectively identifying patients most likely to respond or least likely to experience harm; however, its systematic integration into drug development remains inconsistent outside oncology.
Ingrid Holst‐Laubjerg, José M.A. Moreira   +1 more
wiley   +1 more source

Real-world usage and effectiveness of recombinant factor IX Fc in haemophilia B from the B-SURE study in France. [PDF]

Ther Adv Hematol
Chambost H, Repessé Y, Genre-Volot F, Desprez D, Castet SM, Vanderbecken S, Zidi M, Gandossi C, Nüesch E, Palmborg H, Santagostino E, B-SURE Study Group .   +11 more
europepmc   +1 more source