Results 151 to 160 of about 18,669 (233)

Budget impact analysis of extended half-life recombinant factor IX (rFIXFc) in the treatment of haemophilia B. [PDF]

open access: yesGlob Reg Health Technol Assess, 2020
Aiello A   +4 more
europepmc   +1 more source

Peripheral Seal Composite Barrier (PSCB) for Management of Palatal Donor Sites in Mucogingival Surgery: A Randomized Clinical Trial

open access: yesClinical and Experimental Dental Research, Volume 12, Issue 5, October 2026.
ABSTRACT Objectives Management of the palatal donor site following periodontal plastic surgery remains challenging because of postoperative pain, bleeding, and patient discomfort. This study aimed to evaluate the efficacy of a chairside‐fabricated composite barrier in reducing morbidity at the palatal donor site.
Moein Khojaste   +2 more
wiley   +1 more source

Factor VIII inhibitors demonstrate type I or type II kinetics in high‐titre alloantibodies and autoantibodies

open access: yesClinical and Translational Discovery, Volume 6, Issue 5, October 2026.
The inhibitor kinetics type cannot be used by itself to determine auto‐ versus allo‐anti‐FVIII antibody type. To characterise inhibitor kinetics in inherited haemophilia A (HA) and acquired haemophilia A (AHA) patients in our centre, results show that inhibitors for both HA alloantibodies and AHA autoantibodies may exhibit either type I or type II ...
Cuicui Qiao   +10 more
wiley   +1 more source

Teaching Cell and Gene Therapy in Genetic Counseling Programs: Survey Findings and Suggested Practical Resources for Integration

open access: yesJournal of Genetic Counseling, Volume 35, Issue 5, October 2026.
ABSTRACT As cell and gene therapies (CGTs) advance through clinical trials into clinical practice, it becomes increasingly important for genetic counselors (GCs) to understand these therapeutics to discuss them with patients. Despite the apparent need for GCs to obtain CGT‐related education, little is known about the training GCs receive on CGT topics ...
Mariel Sebby   +4 more
wiley   +1 more source

Red lines and green lights: Gene therapy for inherited erythroid disorders beyond the haemoglobinopathies

open access: yesBritish Journal of Haematology, Volume 209, Issue 4, Page 1469-1481, October 2026.
Gene therapy is revolutionizing treatment paradigms for haemoglobinopathies, establishing a translational framework for disorders that impact red blood cell development. In their paper, Joshi et al. describe the preclinical and early clinical landscape of gene therapies for non‐haemoglobinopathy erythroid disorders and highlight common thematic ...
Gaurav Joshi   +3 more
wiley   +1 more source

An Automated Microfluidic System for Haemostasis Assessment in Cirrhosis With Thrombocytopenia

open access: yesLiver International, Volume 46, Issue 10, October 2026.
ABSTRACT Background & Aims Conventional laboratory tests do not capture platelet–vessel wall interactions (primary haemostasis) occurring in vivo, limiting guidance before invasive procedures. This is relevant in patients with thrombocytopenia, hallmark of advanced cirrhosis. Microfluidic assays may overcome these limitations.
Niccolò Bitto   +14 more
wiley   +1 more source

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