Results 211 to 220 of about 12,995,996 (318)
Joint health and treatment modalities in Nordic patients with moderate haemophilia A and B – The MoHem study [PDF]
Ragnhild J. Måseide+9 more
openalex +1 more source
The halfspace depth generalizes quantiles to multivariate data. This is a bagplot—a depth‐based analog of a boxplot. It succinctly captures the geometry of the bivariate dataset (blue/red points) and identifies the four red points in the top left corner as deviating from the general pattern of the data.
Stanislav Nagy
wiley +1 more source
Medical conditions associated with Prolonged Activated Partial Thromboplastin time in Swat
Background: APPT is a commonly requested laboratory test in various bleeding conditions and as a screening test preoperatively. It is also used to monitor heparin therapy.
Mukamil Shah+4 more
doaj
Recent Advances in mRNA Delivery Systems for Cancer Therapy
This review systematically investigates the applications of mRNA therapy in cancer treatment, with particular emphasis on nonviral delivery systems, targeting strategies, stimulus‐responsive systems, and local delivery methods. Concluding with a meticulous evaluation, the review sheds light on the prevailing challenges while illuminating promising ...
Zheng Zhang+9 more
wiley +1 more source
IntroductionProphylaxis is considered the optimal treatment for persons with moderate to severe haemophilia (factor activity between 1\u20135% of normal and
core
Progress towards gene therapy for haemophilia B [PDF]
Nishil Patel+3 more
openalex +1 more source
ABSTRACT Background Up to 50% of patients with ST‐segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (pPCI) develop coronary microvascular dysfunction (CMD). Aims This study aims to assess whether a prothrombotic state of coronary blood, defined by thromboelastography (TEG), is associated with post ...
Roberto Scarsini+15 more
wiley +1 more source
Pregnancy outcomes in female carriers of haemophilia B Leyden [PDF]
Jinal Gandhi+3 more
openalex +1 more source
Impact of Model‐Informed Drug Development on Drug Development Cycle Times and Clinical Trial Cost
Model‐informed drug development (MIDD) integrates data to quantify benefit/risk informing objective drug discovery and development decisions. An additional critical benefit of MIDD is postulated to be improvement in trial and program efficiencies. While the application of MIDD has grown, there have been no clear examples across programs to demonstrate ...
Vaishali Sahasrabudhe+4 more
wiley +1 more source