Results 131 to 140 of about 149,904 (274)

Meningite a Haemophilus influenzae Serotipo A e por Adenovírus: Caso Raro de Coinfeção em Lactente de Seis Meses

open access: yesActa Médica Portuguesa
O Haemophilus influenzae serotipo A é uma causa rara de meningite e doença invasiva em idade pediátrica. Um lactente de seis meses deu entrada no serviço de urgência por quadro de febre, tosse e rinorreia.
Inês Mazeda   +4 more
doaj   +1 more source

Intra‐Tissue Bacteriome and Cellular Profiles in Periodontal Granulation Tissue From Osseous Defects and Extraction Sockets

open access: yesJournal of Clinical Periodontology, Volume 53, Issue 5, Page 806-820, May 2026.
ABSTRACT Aim To investigate the intra‐tissue bacteriome and cell profiles within periodontal granulation tissue (PGT) for exploring the biological essence and translational potentials. Materials and Methods PGT samples were collected from 49 patients with severe periodontitis—including those from osseous defects (GT) during periodontal surgery ...
Tianfan Cheng   +9 more
wiley   +1 more source

Vaccination Coverage and Factors Associated With Incomplete Vaccination Schedules in Children Under 5 in a Peripheral Area of the Federal District of Brazil

open access: yesPublic Health Nursing, Volume 43, Issue 3, Page 543-553, May/June 2026.
ABSTRACT Objective To estimate vaccination coverage (VC) and analyze the factors associated with the incomplete vaccination schedule (IVS) in children under 5 years of age in two Basic Health Units in the Federal District of Brazil. Design A cross‐sectional study.
Ivea Rayane Mendes Nicacio Viana   +1 more
wiley   +1 more source

The Role of Cytomegalovirus, Haemophilus Influenzae and Epstein Barr Virus in Guillain Barre Syndrome

open access: yesActa Medica Iranica, 2013
Guillain Barre Syndrome (GBS) is an inflammatory, usually demyelinating, polyneuropathy; clinically characterized by acute onset of symmetric progressive muscle weakness with loss of myotatic reflexes.
Shahriar Nafissi   +4 more
doaj  

Biocatalytic Potential of a Mycobacterial Aminoacylase for Synthesis of N‐Acyl‐L‐Amino Acids in Aqueous Media

open access: yesChemBioChem, Volume 27, Issue 7, 14 April 2026.
The aminoacylase MsAA is a suitable enzyme for the biotechnological production of N‐acyl‐L‐amino acids. This study focuses on the optimization of the synthesis of N‐lauroyl‐L‐methionine. A detailed analysis of the catalytic reaction mechanism of MsAA is performed in an in silico protein modeling study.
Jessika Wirges   +11 more
wiley   +1 more source

The Epidemiology of Sickle Cell Disease in Sub‐Saharan Africa: Current Knowledge and Gaps to be Filled

open access: yesAmerican Journal of Hematology, Volume 101, Issue S1, Page 5-16, April 2026.
What are the available data on incidence & prevalence prognosis risk factors of severity of sickle cell disease in sub‐Saharan Africa? ABSTRACT Sickle Cell Disease (SCD) is highly prevalent in sub‐Saharan Africa. Epidemiological data remain sparse, but regional screening and research initiatives are expanding.
Brigitte Ranque   +2 more
wiley   +1 more source

Why, Immunologically, Housing‐Related Fungi and Endotoxins (and Other Chronic Pro‐Inflammatory Stressors) Risk Latent Tuberculosis Reactivation, Severe Asthma, and Translocating and Invasive Infections in Indigenous Communities in Canada

open access: yesAmerican Journal of Human Biology, Volume 38, Issue 4, April 2026.
ABSTRACT Type 1/M1/TH1 and type 3/M1/TH17 pro‐inflammatory switches are risks for latent Mycobacterium tuberculosis (Mtb) reactivation and ongoing infection transmission. This paper considers the heavy toll of reactivation risk in Indigenous communities in Canada and the chronic, everyday pro‐inflammatory stressors connected with type 3/M1/TH17 immune ...
Stacie Burke
wiley   +1 more source

Decoding the Pathophysiology of Autoimmune Diseases—Mechanism, Triggers, and Nanotherapeutics: A Review

open access: yesAdvanced NanoBiomed Research, Volume 6, Issue 4, April 2026.
This review highlights how autoimmune diseases arise from intertwined immunological, genetic, and environmental factors, emphasizing gut microbiota dysbiosis as a pivotal driver. It outlines emerging nanotechnology‐based strategies—such as liposomes, hydrogels, and polymeric nanoparticles—that enhance targeted drug delivery, minimize systemic toxicity,
Md. Meraj Ansari   +5 more
wiley   +1 more source

Influence of Gut Microbiota on Response to Immune Check Point Inhibitors in MASLD Patients With HCC: Unraveling the Connection

open access: yesCancer Medicine, Volume 15, Issue 4, April 2026.
ABSTRACT Immune checkpoint inhibitors (ICIs) have emerged as a promising treatment for various cancers, including advanced hepatocellular carcinoma (HCC). However, a significant proportion of patients with HCC, particularly those with metabolic dysfunction‐associated liver disease (MASLD), exhibit resistance to ICI therapy.
Mazen Elsheikh   +9 more
wiley   +1 more source

Characterization of the Oral Bacteria in Patients With Neuroendocrine Tumors of the Pancreas

open access: yesCancer Medicine, Volume 15, Issue 4, April 2026.
ABSTRACT The primary objective of this study was to investigate dysbiosis in the oral microbiota of patients with pancreatic neuroendocrine tumors (pNETs) and to identify potential biomarkers for clinical diagnosis and prognostic evaluation of pNETs. Healthy controls and pNETs patients were recruited from our hospital.
Jiayue Yao   +4 more
wiley   +1 more source

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