Multi-Component Vaccine Candidates Against Non-Typeable Haemophilus influenzae
Background: Haemophilus influenzae (Hi), a Gram-negative bacterium, is divided into two broad categories: encapsulated and non-capsulated isolates, also called non-typeable Hi isolates (NTHi).
Nouria Belkacem +2 more
doaj +1 more source
The Landscape of Realized Homologous Recombination in Pathogenic Bacteria [PDF]
Recombination enhances the adaptive potential of organisms by allowing genetic variants to be tested on multiple genomic backgrounds. Its distribution in the genome can provide insight into the evolutionary forces that underlie traits, such as the ...
Didelot, X +6 more
core +2 more sources
Invasive Disease Caused by Nontypeable Haemophilus influenzae
These infections are emerging worldwide, especially in young children and the elderly.
J. Langereis, M. D. de Jonge
semanticscholar +1 more source
Chronic rhinosinusitis with nasal polyps (CRSwNP) is a heterogeneous inflammatory condition. Dysbiosis is commonly observed. This study identified distinct sinonasal microbial communities in CRSwNP patients and explored their clinical and pathological associations. Two distinct microbial communities were identified: community type 1 (CT1), dominated by
Bixing Fang +10 more
wiley +1 more source
The prevalence of antimicrobial resistance among Haemophilus spp. is a critical concern, but high-level quinolone-resistant strains had not been isolated from children. We isolated high-level quinolone-resistant H.
Emi Tanaka +5 more
doaj +1 more source
Susceptibility of conjunctival bacterial pathogens to fluoroquinolones. A comparative study of ciprofloxacin, norfloxacin and ofloxacin [PDF]
In order to determine the most common bacteria implicated in conjunctivitis, and the effectiveness of the antibiotic Fluoroquinolone for its treatment, a total of 50 subjects (100 ) eyes, between the ages of 1-30 years with mean age of 16.94 ± 8.06 years
Faustina, Dr Idu, Odjimogho, Ms Stella
core +1 more source
Resistance decay in individuals after antibiotic exposure in primary care: A systematic review and meta-analysis [PDF]
Background Antibiotic resistance is an urgent global problem, but reversibility is poorly understood. We examined the development and decay of bacterial resistance in community patients after antibiotic use.
Bakhit, Mina +5 more
core +1 more source
Molecular characterisation of a meropenem-resistant Haemophilus influenzae [PDF]
Yuan Yi Constance Chen +2 more
openalex +1 more source
This study analyzed the clinical data of 52 patients with moderate‐to‐severe bronchiectasis who were admitted to our hospital. It explored the diagnostic value of bronchoalveolar lavage fluid (BALF) metagenomic next‐generation sequencing (mNGS) in identifying infectious pathogens in patients with moderate‐to‐severe bronchiectasis, and clarified the ...
Jiachun Li +6 more
wiley +1 more source
Service evaluation to establish the sensitivity, specificity and additional value of broad-range 16S rDNA PCR for the diagnosis of infective endocarditis from resected endocardial material in patients from eight UK and Ireland hospitals [PDF]
Infective endocarditis (IE) can be diagnosed in the clinical microbiology laboratory by culturing explanted heart valve material. We present a service evaluation that examines the sensitivity and specificity of a broad-range 16S rDNA polymerase chain ...
Alshafi, K +8 more
core +1 more source

