Results 111 to 120 of about 3,286,663 (345)

Diagnosis of Upper and Lower Respiratory Tract Bacterial Infections with the Use of Multiplex PCR Assays

Diagnostics, 2013
The investigation of respiratory infections by molecular techniques provides important information about the epidemiology of respiratory disease, especially during the post-vaccination era.
Jenny Kourea-Kremastinou, Georgina Tzanakaki, Panayotis Markoulatos, Olga Paniara, Antonia Makri, Athina Argyropoulou, Aliki Voyiatzi, Maria Sioumala, Maria Tsolia, Athanasia Xirogianni   +9 more
doaj   +1 more source

Crystal Structure and Functional Characterization of YjgK From Salmonella Typhimurium

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT The YhcH/YjgK/YiaL (DUF386) family, widely conserved across bacterial species, is involved in essential cellular processes yet remains poorly characterized. YjgK from Salmonella enterica serovar Typhimurium has drawn attention because of its potential role in biofilm formation associated with metal homeostasis, which may be critical for ...
Su‐Yeon Choi, Eunsuk Kim, Hyunjin Yoon, Ha‐Neul Kim, Ji‐Hun Kim, Seung‐Hyeon Seok, Min‐Duk Seo   +6 more
wiley   +1 more source

Lactoferrin. A natural glycoprotein involved in iron and inflammatory homeostasis [PDF]

, 2017
Human lactoferrin (hLf), an iron-binding multifunctional cationic glycoprotein secreted by exocrine glands and by neutrophils, is a key element of host defenses.
Cutone, Antimo, Lepanto, Maria Stefania, Paesano, Rosalba, Rosa, Luigi, Valenti, Piera   +4 more
core   +2 more sources

From Membrane Composition to Antimicrobial Strategies: Experimental and Computational Approaches to AMP Design and Selectivity

Small, EarlyView.
Antimicrobial peptides (AMPs) are promising candidates for next‐generation antibiotics, acting through mechanisms such as membrane disruption and intracellular targeting. This review examines how variations in bacterial membrane composition critically influence AMP activity.
Paolo Rossetti, Marius F.W. Trollmann, Christina Wichmann, Thomas Gutsmann, Christian Eggeling, Rainer A. Böckmann   +5 more
wiley   +1 more source

The Mechanism of NLRP3 Inflammasome Activation and Its Roles in Chronic Rhinosinusitis

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT NLRP3 (NLR family pyrin domain containing 3) is one of the crucial receptors in pathogen recognition receptor (PRR) families which can recognize the pathogen‐associated molecular patterns (PAMPs) and the damage‐associated molecular patterns (DAMPs), thus triggering innate immune response. After NLRP3 activation, it recruits the adaptor protein
Dong‐Lin Li, Yue Li, Yan‐Jie Jiang, Ge‐Hua Zhang, Li‐Hong Chang   +4 more
wiley   +1 more source

Molecular tools for differentiation of nontypeable Haemophilus influenzae from Haemophilus haemolyticus

Frontiers in Microbiology, 2014
Nontypeable Haemophilus influenzae (NTHi) and Haemophilus haemolyticus are closely related bacteria that reside in the upper respiratory tract. NTHi is associated with respiratory tract infections that frequently result in antibiotic prescription whilst ...
Janessa ePickering, Peter C Richmond, Peter C Richmond, Lea-Ann S Kirkham, Lea-Ann S Kirkham   +4 more
doaj   +1 more source

Younger Age and Viral Triggers Were Associated With Post‐Infectious Bronchiolitis Obliterans in French Children

Acta Paediatrica, EarlyView.
ABSTRACT Aim Post‐infectious bronchiolitis obliterans (PIBO) is a rare but severe chronic paediatric obstructive lung disease, characterised by the obliteration of small airways following severe lower respiratory tract infections. Epidemiological data in Europe remain limited. Methods This multicentre retrospective study examined the characteristics of
Julie Mazenq, Marine Crebassa, Alice Hadchouel, Souad Ghattas, Philippe Reix, Laurianne Coutier, Christophe Marguet, Nadia Nathan, Lisa Giovannini‐Chami, Caroline Thumerelle, François Galode, Marie‐Catherine Renoux, Léa Roditis, Eglantine Hullo, Pierrick Cros, Laurence Weiss, Sébastien Kiefer, Marie Tochon, Brahim Allali, Katia Bessaci Kabouya, Céline Delestrain, Louisa Goumidi, Hortense Petat, Véronique Houdouin, Jean‐Christophe Dubus   +24 more
wiley   +1 more source

Identification of dfrA14 in two distinct plasmids conferring trimethoprim resistance in Actinobacillus pleuropneumoniae [PDF]

, 2015
OBJECTIVES: The objective of this study was to determine the distribution and genetic basis of trimethoprim resistance in Actinobacillus pleuropneumoniae isolates from pigs in England.
Alexander W. Tucker, Andrew N. Rycroft, Brendan W. Wren, Clinical and Laboratory Standards Institute, de Groot, Duncan J. Maskell, Janine T. Bossé, Jon Rogers, Lucy A. Weinert, Matt T. G. Holden, Olusegun Oshota, Paul R. Langford, Roberto Fernandez Crespo, Roy R. Chaudhuri, Stephanie Walker, Susanna M. Williamson, Tom Atherton, Yanwen Li   +17 more
core   +3 more sources

Polyarticular Septic Arthritis Caused by Haemophilus influenzae Serotype f in an 8-Month-Old Immunocompetent Infant: A Case Report and Review of the Literature

Case Reports in Orthopedics, 2015
Background. The standard use of vaccinations against pathogens has resulted in a decreased incidence of musculoskeletal infections caused by these previously common bacterial pathogens.
Raheel Ahmed Ali, Sheldon L. Kaplan, Scott B. Rosenfeld   +2 more
doaj   +1 more source

The Aetiology of Elevated Total Serum Immunoglobulin E in Children

Acta Paediatrica, EarlyView.
ABSTRACT Aim The paucity of real‐world data on the aetiology of elevated total serum immunoglobulin E (TS‐IgE) in children afflicts families and health care systems with diagnostic uncertainty. We explored a cohort of children with TS‐IgE levels over 1000 kU/L, focusing on the prevalence of atopic and non‐atopic conditions, the aetiology of extremely ...
Aliisa Ärölä, Kaarina Kukkonen, Svetlana Vakkilainen   +2 more
wiley   +1 more source