Results 131 to 140 of about 883,171 (266)
Meningococcal Disease in Older Adults: Challenges in Diagnosis and Management
Invasive meningococcal disease (IMD) in older adults frequently presents with atypical clinical manifestations, including bacteremic pneumonia, often without classical meningeal signs or sepsis, which presents clinicians with diagnostic challenges, and ...
Muhamed-Kheir Taha +4 more
doaj +1 more source
Microbial and host‐derived biomarkers for the diagnosis and management of peri‐implant diseases
Abstract Objectives To critically evaluate the current evidence on microbial and host‐derived biomarkers for the diagnosis and management of peri‐implant diseases, with emphasis on their biological relevance, potential clinical utility, and current translational limitations.
Su Sheng Quach +5 more
wiley +1 more source
This bibliometric mapping of 1746 publications (2000–2025) charts molecular diagnostics for WHO priority bacterial pathogens across platforms, targets, and resistance markers. Conventional PCR/NAAT and whole‐genome sequencing emerge as complementary core platforms, and the field evolves from targeted pathogen detection into an AMR‐centered ...
Selahattin Ünlü
wiley +1 more source
Gastrointestinal Microbiome Dysbiosis in Cancer Development: Mechanisms and Biomarker Potential
Dysbiosis of the gastrointestinal microbiome plays a role in carcinogenesis by inducing chronic inflammation, DNA damage, and activation of signaling pathways such as NF‐κB, STAT3, and Wnt/β‐catenin. Microorganisms such as Helicobacter pylori, Fusobacterium nucleatum, and Bacteroides fragilis promote the development of gastrointestinal tumors through ...
Negar Asgari +2 more
wiley +1 more source
Active Bacterial Core Surveillance (ABCs) Report Emerging Infections Program Network : Haemophilus influenzae, 2000 [PDF]
ABCs Areas: California (3 county San Francisco Bay area); Connecticut; Georgia; Maryland; Minnesota; New York (15 county Rochester/Albany area);Oregon;Tennessee (11 county area).ABCs Population: The surveillance areas represent 33,327,077 persons. Source:
core
Mucosal‐Associated Invariant T Cells in Health and Disease
The roles of MAIT cells in health and disease and their therapeutic applications. In healthy individuals, riboflavin metabolites secreted by commensal bacteria at mucosal sites are presented by MR1, leading to the activation of MAIT cells. Activated MAIT cells can maintain the barrier integrity of mucosal tissues in a steady state or migrate to the ...
Yu Zhao +5 more
wiley +1 more source
International audienceIntroduction & AimsInvasive infections due to Haemophilus influenzae became less frequent since the implementation of vaccination againstH. influenzae of serotype b.
Deghmane, Ala-Eddine +4 more
core +1 more source
Structural Insights Into the Function of Leishmania major Adenylosuccinate Lyase
ABSTRACT One of several intriguing aspects of kinetoplastid biochemistry is the complete dependence on host purines and purine recycling due to the lack of a de novo purine biosynthesis pathway. Adenylosuccinate lyase (ASL, EC 4.3.2.2) is a key enzyme in the purine synthesis pathway responsible for the conversion of adenylosuccinate into adenosine ...
Ivan R. e Silva +10 more
wiley +1 more source
ABSTRACT Background Bloodstream infections remain a major cause of mortality among cancer patients. Pathogen surveillance and risk stratification tools are key to improved management. This study describes trends in causative pathogens and explores risk factors for positive blood cultures (PBCs) and post‐infection mortality in cancer patients.
Mathias Holmsgaard Eskesen +7 more
wiley +1 more source
Guillain Barre Syndrome (GBS) is an inflammatory, usually demyelinating, polyneuropathy; clinically characterized by acute onset of symmetric progressive muscle weakness with loss of myotatic reflexes.
Shahriar Nafissi +4 more
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