Pathogen-targeted quick multiplex PCR identification of <i>Chlamydia psittaci</i> and <i>Haemophilus influenzae</i> coinfection in pneumonia: a case report. [PDF]
Yuan Y +7 more
europepmc +1 more source
A Global Perspective of Childhood Vaccinations: Past, Present, and Future—From Smallpox to mRNA
ABSTRACT Childhood immunisation is one of the most successful public health interventions in history, preventing millions of deaths and substantially reducing global child mortality. This mini‐review summarises the historical development of childhood vaccines, the role of global coordination in expanding immunisation coverage, and the innovations that ...
Tobias Alfvén, Tania Reza, Alieu Sowe
wiley +1 more source
Nasopharyngeal Microbiome Composition and its Clinical Correlates in Children Hospitalized with Severe Pneumonia in East Africa. [PDF]
Makori TO +16 more
europepmc +1 more source
When a Neisseria meningitidis PCR limitation contributes to an immunological disease diagnosis
Claire Duployez +7 more
doaj +1 more source
A comparative study of mNGS and tNGS for pathogen detection in paired upper and lower respiratory tract specimens from pediatric pneumonia patients. [PDF]
Zhao J +7 more
europepmc +1 more source
Trained Immunity in Childhood Vaccination
Trained immunity as an emerging concept in paediatric vaccinology. Trained immunity links vaccine stimuli through epigenetic and metabolic reprogramming to enhanced innate immune cell function, thereby strengthening protection against diverse pathogens while promoting adaptive immune responses through more efficient antigen presentation and co ...
ChenRongRong Cai +2 more
wiley +1 more source
The respiratory microbiome influences the occurrence of respiratory diseases in children. [PDF]
Zheng K +5 more
europepmc +1 more source
ABSTRACT Asthma and atopic dermatitis (AD) are common childhood inflammatory diseases linked to type 2 immune responses and early‐life environmental factors. Emerging evidence suggests that nasopharyngeal microbiota and immune‐regulatory cytokines may influence disease development.
Johanna T. Teräsjärvi +4 more
wiley +1 more source
Epidemiology and antimicrobial resistance trends in <i>Haemophilus parainfluenzae</i> in a tertiary care hospital (2018-2022). [PDF]
Saiz-Escobedo L +13 more
europepmc +1 more source
The Cytokine Response of Circulating Immune Cells to Rhinovirus (RV‐A16) is Reduced in Severe Asthma
ABSTRACT Severe asthma patients (SA) are more susceptible to respiratory infections with human rhinoviruses (HRV) than healthy subjects (H), causing exacerbations. In response to HRV, circulating immune cells are recruited to and activated at the local sites of infection.
Kaschin Jamal Jameel +10 more
wiley +1 more source

