Results 91 to 100 of about 64,183 (238)

De novo or Salvage? Nucleotide Availability as a Driver of Bacterial Adaptation and Virulence

MicrobiologyOpen, Volume 15, Issue 4, August 2026.
Bacterial pathogens survive in different host environments by switching between making nucleotides by de novo synthesis and scavenging them from the host. This flexibility supports growth and virulence making nucleotide metabolism an attractive therapeutic target.
Riya Joshi, Alastair G. McEwan, Ulrike Kappler   +2 more
wiley   +1 more source

A severe asthma phenotype of excessive airway Haemophilus influenzae relative abundance associated with sputum neutrophilia

Clinical and Translational Medicine
Background Severe asthma (SA) encompasses several clinical phenotypes with a heterogeneous airway microbiome. We determined the phenotypes associated with a low α‐diversity microbiome.
Ali Versi, Adnan Azim, Fransiskus Xaverius Ivan, Mahmoud I Abdel‐Aziz, Stewart Bates, John Riley, Mohib Uddin, Nazanin Zounemat Kermani, Anke‐H Maitland‐Van Der Zee, Sven‐Eric Dahlen, Ratko Djukanovic, Sanjay H Chotirmall, Peter Howarth, Ian M Adcock, Kian Fan Chung, the U‐BIOPRED study group   +15 more
doaj   +1 more source

Antibacterial effect of Medicago sativa extract on the common bacterial in sinusitis infection [PDF]

International Journal of Biomedicine and Public Health, 2018
Introduction: Sinusitis is a serious health hazard that is caused by inflammation of the surrounding sinus. Bacterial infection due to Streptococcus pneumonia microorganisms, Haemophilus influenzae, Moraxella catarrhalis and Staphylococcus aureus one of ...
Hamid Chegini, Mozhgan Oshaghi, Mohammad Amin Boshagh, Poorya Foroutan, Amir Hossein Jahangiri   +4 more
doaj  

Cathepsin B, Airway Pathogens, and Inflammation in the Lower Airways of Children With Cystic Fibrosis

Pediatric Pulmonology, Volume 61, Issue 8, August 2026.
ABSTRACT Introduction Dysregulated protease activity contributes to airway inflammation and tissue remodeling in cystic fibrosis (CF); however, the role of the lysosomal cysteine protease Cathepsin B (CTSB) remains incompletely defined. This cross‐sectional study investigates relationships between pro‐CTSB and mature CTSB activity with CF‐specific ...
Matthew K. Fought, John B. O'Connor, Brandie D. Wagner, Alexandra C. Quinn, J. Kirk Harris, Theresa A. Laguna   +5 more
wiley   +1 more source

Etiological Trends and Antibiotic Susceptibility of Bacterial Strains Causing Respiratory Tract Infections

Pakistan Journal of Medicine and Dentistry
Background: Lower respiratory tract infections (LTRIs) are emerging as the most common infectious diseases of humans. Antibiotic resistance has increased in all the major pathogens therefore, this project engrossed on defining the current drift of ...
Fareeha Adnan, Faisal IqbalAfridi, Nazia Kurshid   +2 more
doaj   +1 more source

Modeling the lung‒brain axis in critical illness: Multifactorial crosstalk through organoids and organ‐on‐a‐chip system

VIEW, Volume 7, Issue 4, August 2026.
Patients in intensive care units often experience lung injuries, complicated by brain problems. Advanced laboratory tools, organoids, and organs‐on‐chips facilitated the study of multiorgan interactions, help us understand the communication between the lungs and brain.
Wanyi Zhang, Ting Wang, Mengying Yao, Longxiang Su, Lixin Xie, Pan Pan   +5 more
wiley   +1 more source

Haemophilus Influenzae [PDF]

Scottish Medical Journal, 1974
openaire   +3 more sources

Haemophilus influenzaeType b Meningitis in the Short Period after Vaccination: A Reminder of the Phenomenon of Apparent Vaccine Failure [PDF]

, 2012
Noa Greenberg‐Kushnir, Orly Haskin, Havatzelet Yarden‐Bilavsky, Jacob Amir, Efraim Bilavsky   +4 more
openalex   +1 more source

Iron Physiology and Its Impact on Atopic Diseases: An EAACI Taskforce Report

Allergy, Volume 81, Issue 8, Page 2675-2712, August 2026.
ABSTRACT Iron is essential for oxygen transport, energy metabolism, and immune regulation. Yet iron deficiency is the most common micronutrient disorder across all age groups, affecting nearly one quarter of the global population. Iron deficiency triggers nutritional immunity, a host defense mechanism that withholds and redistributes iron, contributing
Franziska Roth‐Walter, Ioana Agache, Beatriz Cabanillas, Roberto Berni Canani, Pasquale Comberiati, Holger Garn, Cristina Gomez‐Casado, Karin Hufnagl, Ekaterina Khaleva, Gregorio P. Milani, Daniel Munblit, Nikolaos Douladiris, Liam O'Mahony, Frank Redegeld, Carmen Riggioni, Peter K. Smith, Betty van Esch, Emilia Vassilopoulou, Carina Venter, Diego G. Peroni   +19 more
wiley   +1 more source

Immunochemical characterization of variable epitopes of outer membrane protein P2 of nontypeable Haemophilus influenzae [PDF]

, 1991
L van Alphen, Paul P. Eijk, L Geelen-van den Broek, J. Dankert   +3 more
openalex   +1 more source