Results 111 to 120 of about 25,084 (169)

Polyphenol‐Based Biomaterials for Antibacterial Infection Management: From Assembly Chemistry to Infection Site‐Specific Therapeutic Platforms

cMat, Volume 3, Issue 3, September 2026.
Polyphenol assembly chemistry provides a versatile basis for antibacterial biomaterials. Matching material format and function to the distinct barriers of wound, respiratory, intestinal, and implant‐associated infections is central to effective and translatable design. ABSTRACT Bacterial infections involving multidrug‐resistant pathogens and persistent
Wei Yang, Li Wan, Ming Wen, Haiyan He, Hongliang Tan   +4 more
wiley   +1 more source

A First‐in‐Japanese Phase 1, Double‐Blind, Placebo‐Controlled, Parallel‐Cohort Study of Sefaxersen, an Antisense Oligonucleotide Targeting Complement Factor B, in Healthy Participants

Clinical Pharmacology in Drug Development, Volume 15, Issue 9, September 2026.
Abstract Increased activity in the complement alternative pathway (AP) plays a key role in diseases such as IgA nephropathy (IgAN). This first‐in‐Japanese double‐blind Phase 1 study investigated the pharmacokinetics (PK), pharmacodynamics (PD), safety, and tolerability of sefaxersen (RO7434656), an antisense oligonucleotide targeting complement factor ...
Takakazu Sato, Hiroyuki Fukase, Takaaki Ishida, Arisa Karasawa   +3 more
wiley   +1 more source

Case of invasive nontypable Haemophilus influenzae respiratory tract infection with a large quantity of neutrophil extracellular traps in sputum

, 2012
Shigeto Hamaguchi,1,* Masafumi Seki,1,* Norihisa Yamamoto,1 Tomoya Hirose,2 Naoya Matsumoto,2 Taro Irisawa,2 Ryosuke Takegawa,2 Takeshi Shimazu,2 Kazunori Tomono11Division of Infection Control and Prevention, 2Department of Traumatology and Acute ...
Yamamoto N, Hamaguchi S, Takegawa R, Hirose T, Seki M, Matsumoto N, Irisawa T, Shimazu T, Tomono K   +8 more
core  

Biofilm-associated haemophilus influenzae in genital infections: a potential target for therapeutic intervention

International audienceBackground: Haemophilus influenzae is increasingly implicated in women genital infections and septic abortion. This study characterizes H.
Belkacem, Nouria, Hong, Eva, Deghmane, Ala-Eddine, Taha, Muhamed-Kheir, Terrade, Aude   +4 more
core   +1 more source

Causes and Contributing Factors of In‐Hospital and Post‐Discharge Mortality Among Patients With Severe Acute Respiratory Infection in Low‐ and Middle‐Income Countries: A Scoping Review

Health Science Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background and Aims Severe acute respiratory infections (SARI) remain a major cause of global morbidity and mortality, with a disproportionate burden in low‐ and middle‐income countries (LMICs). Although in‐hospital mortality is frequently reported, deaths occurring after hospital discharge remain poorly documented.
Md Ariful Islam, Holly Seale, Md Saiful Islam, Saju Bhuiya, Md Zakiul Hassan, Quazi Fayeza Sultana, Fahmida Chowdhury, Abrar Ahmad Chughtai   +7 more
wiley   +1 more source

Organ‐Specific Human Microbiomes and Dysbiosis: Mechanistic Links to Disease and Emerging Therapeutic Strategies

Journal of Clinical Laboratory Analysis, Volume 40, Issue 18, September 2026.
Schematic overview of the human microbiome and major microbiota‐derived metabolites across body sites, highlighting the gut–brain, gut–heart, and gut–kidney axes in host physiology and disease. ABSTRACT Background The human microbiome is a dynamic and diverse community of microorganisms that affects susceptibility to illness and promotes wellness ...
Awadh Alanazi
wiley   +1 more source

Lateral Mucosal Flap With Steroid‐Eluting Implant in Revision Draf Type III Frontal Sinus Surgery

The Laryngoscope, Volume 136, Issue 9, Page 3732-3736, September 2026.
This technical note introduces a novel endoscopic strategy that integrates a laterally based endonasal mucosal flap with a bioabsorbable steroid‐eluting implant to prevent restenosis following revision of Draf type III frontal sinus surgery. The vascularized flap is stabilized and maintained in close apposition to the underlying bone by a self ...
Mario Turri‐Zanoni, Gloria Schiavo, Marco Valentini, Andrea Presta, Federico Russo, Alessandro Vinciguerra, Paolo Battaglia   +6 more
wiley   +1 more source

Greater Cochlear Damage in Otogenic Versus Meningogenic Meningitis: Hearing Rehabilitation Implications

The Laryngoscope, Volume 136, Issue 9, Page 3998-4005, September 2026.
Otogenic route of meningitis was associated with greater cochlear hair cell loss in comparison with the meningogenic one in this otopathology study. Neuronal depletion has been traditionally implicated in failed hearing rehabilitation of post‐meningitis deafness.
Matheus Pedrosa Tavares, Henrique Furlan Pauna, Rafael da Costa Monsanto, Nevra Keskin‐Yilmaz, Breno Lima de Almeida, Norma de Oliveira Penido   +5 more
wiley   +1 more source

Post‐Mortem Nasal Swab Testing to Reveal Hidden Respiratory Pathogens: Unlocking Public Health Insights in Bangladesh

Medicine Advances, Volume 4, Issue 3, Page 401-407, September 2026.
Respiratory deaths in Bangladesh are frequently assigned non‐specific causes because of limited diagnostic information. Through stakeholder consultations, key informant interviews, microbiologist consultations, and literature review, 11 priority respiratory pathogens were identified for potential detection using post‐mortem nasal swab testing and ...
Ridwana Maher Manna, Aniqa Tasnim Hossain   +1 more
wiley   +1 more source

Clinical Outcomes of Chronic Airway Infection in Primary Ciliary Dyskinesia

Pediatric Pulmonology, Volume 61, Issue 9, September 2026.
ABSTRACT Introduction Primary ciliary dyskinesia (PCD) is a rare disorder of impaired respiratory mucociliary clearance and chronic pulmonary infections. The clinical impact of chronic infection is poorly understood. The objective of this single‐center, retrospective cohort study was to assess clinical outcomes of people with PCD and chronic airway ...
Thomas G. Saba, Madsen Zimbric, Harlan McCaffery, Lindsay J. Caverly   +3 more
wiley   +1 more source