Results 161 to 170 of about 22,412 (245)

Nanomedicine‐driven innovations in postoperative cancer immunotherapy: Remodeling tumor microenvironment and precision delivery strategies

open access: yesBMEMat, EarlyView.
Nanomedicine‐Driven Strategies for Suppressing Postoperative Tumor Recurrence. This schematic illustrates three pivotal nanomedical strategies that synergistically counteract recurrence by targeting residual disease and the immunosuppressive tumor microenvironment within the surgical cavity.
Lisong Pang   +8 more
wiley   +1 more source

Exosome‐mimetic vesicle‐encapsulated multi‐responsive antibacterial hydrogel core‐shell microneedle patch promotes scarless healing of infected wounds

open access: yesBMEMat, EarlyView.
The core‐shell microneedle patch VP@FNV‐CuO2‐MN was fabricated by encapsulating n‐CuO2 in a moderately crosslinked PVA/CMCS/Borax4 hydrogel shell and VP‐loaded fibroblast membrane nanovesicles (VP@FNV) in a highly crosslinked PVA/CMCS/Borax6 hydrogel core. Upon application to an infected wound, the acidic microenvironment triggers Fenton‐like reactions
Ziwei Jiang   +12 more
wiley   +1 more source

Engineering programmable peptide hydrogels for chronic refractory wounds: A mechanism‐driven framework

open access: yesBMEMat, EarlyView.
To break the self‐perpetuating pathology of chronic wounds, we propose a mechanism‐driven engineering framework for peptide‐based hydrogels. This review elucidates a hierarchical strategy—from molecular design to intelligent, multi‐functional systems—that enables these programmable biomaterials to dynamically intervene in key pathological loops and ...
Xiaoyu Lv   +3 more
wiley   +1 more source

Tannic acid–metal biomaterials for skin repair: Principles, immune microenvironment modulation, and translational perspectives

open access: yesBMEMat, EarlyView.
Tannic acid–metal materials are emerging as versatile wound biomaterials, but their value depends on more than multifunctionality. This review maps how tannic acid alone, free metal ions, and coordinated TA–metal systems differ in design logic, immune‐microenvironment effects, and translational potential, offering a practical framework for choosing ...
Shahid Mahmood   +6 more
wiley   +1 more source

Small scale purification and biophysical characterization of haptoglobin derived from human Cohn fraction IV

open access: yesBiotechnology Progress, EarlyView.
Abstract Haptoglobin (Hp) is a polymorphic acute phase α‐2 glycoprotein found in plasma that plays a critical role in binding, neutralizing, and removing cell‐free hemoglobin (Hb) from the circulation. Under clinical conditions characterized by high levels of hemolysis, such as in patients with sickle cell disease (SCD), large quantities of cell‐free ...
Shuwei Lu   +5 more
wiley   +1 more source

Customized three dimensionally printed palatal stents: A randomized controlled clinical trial

open access: yesClinical Advances in Periodontics, EarlyView.
Abstract Background Soft tissue grafts are commonly used in periodontal surgery around teeth and implants. However, few studies have examined donor‐site pain through patient‐reported outcomes following soft tissue grafting. This study aimed to minimize donor‐site pain during autologous gingival grafting using a three‐dimensionally (3D)‐printed stent ...
Mi‐Seon Goh   +4 more
wiley   +1 more source

Disorders of Haemostasis

open access: yesInternational Journal of Clinical Practice, 1964
openaire   +2 more sources

Subperiosteal tunnel assisted graft (STAG) technique: Report of two cases

open access: yesClinical Advances in Periodontics, EarlyView.
Abstract Background This case report describes the clinical application of the subperiosteal tunnel‐assisted graft (STAG) technique, a novel approach for peri‐implant phenotype modification and keratinized tissue augmentation. Although free gingival grafts remain the gold standard for increasing keratinized tissue width, their effectiveness may be ...
Seiko Min
wiley   +1 more source

The Triple Wire Dual Angioseal Technique for Large Bore Femoral Access Closure

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT There is a growing need for large‐bore femoral access across cardiac interventions. This has led to a need for more widely accessible vascular closure techniques to facilitate reliable vascular closure and wider access to these interventions.
Hilal Khan, Mohaned Egred
wiley   +1 more source

GelMA‐Based Hydrogel Encapsulating Astragalus Polysaccharides and Umbilical Cord Mesenchymal Stem Cell Exosomes Promotes Full‐Thickness Skin Wound Healing

open access: yesChronic Diseases and Translational Medicine, EarlyView.
ABSTRACT Background Wound healing involves excessive oxidative stress and cellular dysfunction, while current single therapies remain inadequate. Astragalus polysaccharides (APS) and exosomes (Exos) possess antioxidative and regenerative properties, and gelatin methacryloyl (GelMA) hydrogel provides a biocompatible platform for localized delivery. Here,
Jingwen Tian   +7 more
wiley   +1 more source

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