Results 11 to 20 of about 36,870 (258)

Microfluidics in Haemostasis: A Review [PDF]

Molecules, 2020
Haemostatic disorders are both complex and costly in relation to both their treatment and subsequent management. As leading causes of mortality worldwide, there is an ever-increasing drive to improve the diagnosis and prevention of haemostatic disorders.
Panchal, Heta Jigar, Kent, Nigel, Knox, Andrew, Harris, Leanne   +3 more
openaire   +6 more sources

Haemostasis in hypothyroidism [PDF]

Postgraduate Medical Journal, 1990
SummaryAbnormalities that have been reported for platelet indices and function, coagulation factors and tests, and the fibrinolytic system in hypothyroidism are reviewed. These abnormalities, although usually of limited importance clinically, may occasionally lead to major bleeding episodes and to diagnostic confusion.
H C, Ford, J M, Carter
openaire   +2 more sources

Vascular haemostasis [PDF]

Haemophilia, 2010
Summary.  While the majority of this session will deal with selected inherited vascular abnormalities that may manifest as a haemorrhagic disorder, the initial discussion by Dr Key will focus on the interplay between the vessel wall and components of the coagulation system, with a focus on haemophilia A and B.
Key, N. S., De Paepe, A., Malfait, F., Shovlin, C. L.   +3 more
openaire   +4 more sources

Weight-adjusted dosing of fibrinogen concentrate and cryoprecipitate in the treatment of hypofibrinogenaemic bleeding adult cardiac surgical patients: a post hoc analysis of the Fibrinogen Replenishment in cardiac surgery randomised controlled trial

BJA Open, 2022
Background: Hypofibrinogenaemia is associated with excessive bleeding after cardiac surgery. Our aim was to compare the efficacy and safety of weight-adjusted vs empiric dosing of fibrinogen replacement in cardiac surgery.
Cian Devine, Justyna Bartoszko, Jeannie Callum, Keyvan Karkouti   +3 more
doaj   +1 more source

Identification of reference miRNAs in plasma useful for the study of oestrogen-responsive miRNAs associated with acquired Protein S deficiency in pregnancy

BMC Research Notes, 2017
Background Accumulating evidence indicate that circulating microRNAs (miRNAs) are useful independent non-invasive biomarkers, with unique miRNA signatures defined for various pathophysiological conditions.
J. W. Tay, I. James, Q. W. Hughes, J. Y. Tiao, R. I. Baker   +4 more
doaj   +1 more source

Genetics of haemostasis [PDF]

Haemophilia, 2012
Summary.  Congenital defects of platelets or plasma proteins involved in blood coagulation generally lead to bleeding disorders. In some of these disorders, patients with a severe phenotype are prone to spontaneous bleeds with critical consequences. This situation occurs more commonly in haemophilia A and haemophilia B and to a certain extent in severe
A C, Goodeve, D J, Perry, T, Cumming, M, Hill, I, Jennings, S, Kitchen, I, Walker, E, Gray, G R, Jayandharan, E, Tuddenham   +9 more
openaire   +2 more sources

“COAGULATION”: a mnemonic device for treating coagulation disorders following traumatic brain injury—a narrative-based method in the intensive care unit

Frontiers in Public Health, 2023
IntroductionCoagulopathy associated with isolated traumatic brain injury (C-iTBI) is a frequent complication associated with poor outcomes, primarily due to its role in the development or progression of haemorrhagic brain lesions.
Manuel Quintana-Diaz, Manuel Quintana-Diaz, Manuel Quintana-Diaz, Pasquale Anania, Raúl Juárez-Vela, Raúl Juárez-Vela, Raúl Juárez-Vela, Emmanuel Echaniz-Serrano, Emmanuel Echaniz-Serrano, Clara Isabel Tejada-Garrido, Clara Isabel Tejada-Garrido, Pilar Sanchez-Conde, Kapil Nanwani-Nanwani, Kapil Nanwani-Nanwani, Ainhoa Serrano-Lázaro, Ainhoa Serrano-Lázaro, Pilar Marcos-Neira, María Gero-Escapa, Jorge García-Criado, Daniel Agustín Godoy   +19 more
doaj   +1 more source

Haemostatics in surgery and our experience in the enucleoresection of renal cell carcinoma

World Journal of Surgical Oncology, 2010
Background 30 patients, with T1 renal cell carcinomas (RCC) who underwent open enucleoresection of the tumour, were randomized to the use of a topical haemostatic agent (Floseal) or to an infrared-sapphire coagulator (ISC), to compare their efficacy in ...
Saldutto Pietro, Pace Gianna, Vicentini Carlo, Miano Lucio   +3 more
doaj   +1 more source

1,8-Cineole Affects Agonists-Induced Platelet Activation, Thrombus Formation and Haemostasis

Cells, 2021
1,8-cineole, a monoterpenoid is a major component of eucalyptus oil and has been proven to possess numerous beneficial effects in humans. Notably, 1,8-cineole is the primary active ingredient of a clinically approved drug, Soledum® which is being mainly ...
Kahdr A. Alatawi, Divyashree Ravishankar, Pabitra H. Patra, Alexander P. Bye, Alexander R. Stainer, Ketan Patel, Darius Widera, Sakthivel Vaiyapuri   +7 more
doaj   +1 more source

T2* Magnetic Resonance Imaging Uncovers Hemosiderin Burden in Pediatric Hemophilia: A Call for Sensitive Imaging Biomarkers

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Hemophilic arthropathy remains the leading morbidity in hemophilia despite modern prophylaxis, and early joint damage may be missed by routine exams. This study explored T2* MRI as a noninvasive biomarker of hemosiderin deposition in pediatric hemophilia.
Jessica Garcia, Tarique Hussain, Jeanne Dillenbeck, Matthew Hammer, Annette von Drygalski, Guy Young, Ayesha Zia   +6 more
wiley   +1 more source