Results 21 to 30 of about 653 (147)

Pre-storage leucoreduction of platelet concentrates reduced biological response modifier concentrations and TRALI incidence in an in vivo sheep model [PDF]

Scientific Reports
Transfusion-related acute lung injury (TRALI) is a potentially fatal transfusion reaction. It can be caused by the transfusion of proteins, lipids, and extracellular vesicles that accumulate in blood components during routine storage and are collectively
John-Paul Tung, Gabriela Simonova, Elise Hewlett, Sanne Engkilde Pedersen, Arlanna Esguerra Lallen, Fahad Alkhureeb, Rebecca Wellburn, Sara Chiaretti, Fergal T. Temple, Thy Duong, Michelle Cinel, Corey Giles, Peter J. Meikle, John F. Fraser   +13 more
doaj   +2 more sources

Serological screening for cytomegalovirus in a leucodepleted blood supply: A systematic review. [PDF]

Vox Sang
Abstract Background and Objectives Cytomegalovirus (CMV) causes harm in at‐risk populations. Selection of seronegative donors has been used to prevent transmission. Leucodepletion reduces the potential for CMV transmission; however, the residual risk is uncertain, leading to variability in practice.
Crispin PJ, Edwards D, Beattie K, Brown K, Clarke L, King F, Ormerod A, Ross B.   +7 more
europepmc   +2 more sources

Practices in platelet production: A Nordic perspective (2018-2022). [PDF]

Vox Sang
Abstract Background and Objectives The Nordic region includes Denmark, Finland, Iceland, Norway and Sweden, with a population of >27.5 million. Blood services are managed differently in each country. Current data on platelet concentrate (PC) production methods and capacity are important for developing efficiency and cross‐border preparedness. Materials
Alshamari A, Nahreen T, Ihalainen J, Hemminki A, Landrö R, Knútsdóttir E, Sørensen B, Danilova E, Jacobsen B, Auvinen MK, Ramström S, Abedi MR.   +11 more
europepmc   +2 more sources

Nucleic acid testing in Colombian blood banks (2018-2024): Implementation, yield estimates and implications for safer transfusion policy. [PDF]

Vox Sang
Abstract Background and Objectives Colombia has a population of 52.6 million inhabitants and a blood donation rate of 26 donations per 1000 inhabitants. The 84 blood banks in the country collect approximately 1 million donations annually, which are mandatorily screened for human immunodeficiency virus (HIV), hepatitis B virus (HBV), hepatitis C virus ...
Bermúdez-Forero MI, García-Otálora MA.   +1 more
europepmc   +2 more sources

Fundamentals of big data and artificial intelligence in transfusion medicine. [PDF]

Vox Sang
Abstract Within the digital transformation of medicine, transfusion medicine has quietly become a big‐data discipline. The long‐standing tradition of blood product standardization (e.g., ISBT‐128) and large donor cohorts being followed over years—some of which are sampled in national biobank projects, build a favourable setting.
Turki AT, Brieske CM, Gurkan UA, Scheidler KM, Usta OB, Turkulainen E, Arzideh K, Temme C, Hosch R, Horn PA, Arvas M.   +10 more
europepmc   +2 more sources

Coagulation and Transfusion Informatics in Chronic Liver Disease: A Data Linkage Study of Emergency Department Presentations. [PDF]

EJHaem
This study demonstrates the feasibility of applying a data linkage framework to evaluate coagulation abnormalities and transfusion practices in patients with chronic liver disease (CLD) presenting to emergency departments (EDs). Coagulation and transfusion data are typically fragmented across hospitals and information systems, limiting comprehensive ...
Latona A, Smith E, Grant J, Mitra B.
europepmc   +2 more sources

A framework checklist for implementing bedside electronic transfusion systems. [PDF]

Transfus Med
Abstract Background Every time a unit of blood is given to a patient, it is essential that all steps in the transfusion pathway are executed correctly to ensure that the right blood is transfused to the right patient. Bedside transfusion checks at the point of sampling for compatibility testing, sample labelling and blood administration are an ...
McCullagh J, Makki S, Hancock K, Booth C, Bowles L, Djurdjevic O, Farrar K, Geraci C, Hammond S, Mcaleese H, Murphy MF, Oyekan F, Green L.   +12 more
europepmc   +2 more sources

Tocilizumab provides a potential therapeutic option for the management of hyperhaemolysis syndrome in sickle cell disease: A case series and brief narrative overview of the literature. [PDF]

Transfus Med
Abstract Background and Objectives Hyperhaemolysis syndrome is a life‐threatening complication of transfusion, potentially triggered by macrophage activation, with limited treatment options. Tocilizumab, an anti‐IL6 monoclonal antibody, has mechanistic rationale for use and has been shown to be effective in a small number of cases.
Wolf S, Singh B, Zaidi A, Greaves P, Oyesanya F, Bennett S, Kaya B, Barroso F, Telfer P.   +8 more
europepmc   +2 more sources

Acute Transfusion Reactions in a Tertiary Care Hospital: The Saudi Context

Scientific Journal of King Faisal University: Basic and Applied Sciences, 2022
Although blood transfusion is a life-saving procedure, it can be associated with complications in rare cases. An acute transfusion reaction (ATR) is a complication where recipients exhibit an adverse reaction within 24 hours of a blood transfusion.
Mohrah Alalshaikh, Sarah Abo Baker, Ammar Alsughayir, Yasser Almaki, Leenah Almass, Mohammed Alnamnakani, Alyazeed Alsaif, Abdullah Albarghash, Imran Ahad Pukhta   +8 more
doaj   +1 more source

Reporting Adverse Transfusion Reactions in a Teritary Care Centre, Kerala, India

National Journal of Laboratory Medicine, 2019
Introduction: Therapeutic use of blood and its components has increased in most tertiary care centres and also it carries its own advantages and risks.
T Ramanathan, D Meena, D Sushama
doaj   +1 more source