Results 11 to 20 of about 80 (75)

Impact of exercise training on tumour‐infiltrating T cells in human prostate cancer: A secondary analysis of a randomized controlled trial (PRO‐TEST)

Experimental Physiology, EarlyView.
Abstract Exercise training reduces tumour growth by increasing tumour‐infiltrating T‐cell density in preclinical models. However, it remains unknown whether exercise training can modify intratumoural T cells in humans.The aim of this study was to compare the effects of an exercise training intervention versus control on human prostate intratumoural T ...
Simon Nørskov Thomsen, Emil Wriedt, Marianne Gardar Stærk, Sissal Sigmundsdottir Djurhuus, Birgitte Grønkær Toft, Sabrina Wielsøe, Andreas Røder, Thomas Hasselager, Peter Busch Østergren, Henrik Jakobsen, Klaus Brasso, Jesper Frank Christensen, Louise Lang Lehrskov, Casper Simonsen   +13 more
wiley   +1 more source

Reversible Metamorphosis of a Conjugated Polymer Induced by Photoexcitation

Advanced Photonics Research, Volume 7, Issue 3, March 2026.
Photon absorption in conjugated polymers induces a persistent, reversible transformation in their optoelectronic and structural properties. At elevated temperatures, photoexcitation alters the molecular conformations and (re)organization of polymer molecules within low‐viscosity matrices, resulting in a persistent “photomemory” effect with blue‐shifted
Solomon L. Joseph, Anmol Arya, Günter Reiter   +2 more
wiley   +1 more source

Design of Bayesian Clinical Trials With Clustered Data

Statistics in Medicine, Volume 45, Issue 6-7, March 2026.
ABSTRACT In the design of clinical trials, it is essential to assess the design operating characteristics (e.g., power and the type I error rate). Common practice for the evaluation of operating characteristics in clinical trials that employ Bayesian analysis and decision procedures relies on estimating the sampling distribution of posterior summaries ...
Luke Hagar, Shirin Golchi
wiley   +1 more source

Genetics of infertility and “assisted fertilization” in the Bible: The case of Abraham and his family

Andrology, Volume 14, Issue 3, Page 641-650, March 2026.
Abstract Couple infertility is a very ancient medical condition. One of the first descriptions of familial infertility/subfertility is contained in the first book of the Bible, Genesis, written in the 10th century BC and reporting tales from the oral tradition even occurred about 800 years earlier.
Manuela Simoni, Frank Tüttelmann, Livio Casarini   +2 more
wiley   +1 more source

Management of a diaphragmatic hernia using self‐locking knots

Equine Veterinary Education, Volume 38, Issue 3, Page e105-e110, March 2026.
Summary A 4‐year‐old Thoroughbred gelding was presented with a history of severe colic signs that were non‐responsive to non‐steroidal anti‐inflammatory drugs. During initial evaluation, distended small intestine was observed, together with continued colic signs and a serosanguinous abdominocentesis sample.
A. Gillen, A. Shanklin, A. Graham, A. A. Alvarez, C. Baldwin   +4 more
wiley   +1 more source

Anticancer Molecular Mechanisms of Phytosterols: An Updated Review on Clinical Trials

Food Science &Nutrition, Volume 14, Issue 2, February 2026.
Phytosterols, a form of naturally occurring substance structurally related to cholesterol, have been getting considerable interest due to their possible anticancer properties. Phytosterols induce apoptosis, block the cell cycle, and abrogate the invasion and metastasis of cancer cells, offering a multi‐manifestation treatment of cancer.
Muhammad Shahbaz, Ushna Momal, Asfa Perween, Hammad Naeem, Muzzamal Hussain, Muhammad Imran, Gamal A. Mohamed, Sabrin R. M. Ibrahim, Suliman A. Alsagaby, Waleed Al Abdulmonem, Entessar Al Jbawi, Mohamed A. Abdelgawad, Samy Selim, Soad K. Al Jaouni, Hagar M. Mohamed   +14 more
wiley   +1 more source

Heterotrophic diazotrophy along a river–lake continuum: Lifestyle and contribution to dinitrogen fixation

Limnology and Oceanography, Volume 71, Issue 1, January 2026.
Abstract Heterotrophic diazotrophs are potentially important to the nitrogen cycle in freshwater ecosystems, yet their abundance, N2 fixation rates, diversity, and association with aggregates remain poorly understood. This study elucidates the contribution of freshwater heterotrophic diazotrophs as free‐living or aggregate‐associated cells to total N2 ...
Eyal Geisler, Hagar Siebner, Max Kolton, Guy Sisma‐Ventura, Eyal Rahav, Shai Arnon, Edo Bar‐Zeev   +6 more
wiley   +1 more source

Letter to the editor on exercise and immune competence: using pre‐clinical findings to inform the design of clinical studies

Experimental Physiology, EarlyView.
Amit Hagar
wiley   +1 more source

Orexin/Hypocretin Modulation of Cholinergic Signaling within the Prefrontal Cortex in Response to an Immune Challenge

Alzheimer's &Dementia, Volume 21, Issue S1, December 2025.
Abstract Background The basal forebrain cholinergic hypothesis (BFCS) describes the degeneration of cholinergic neurons in Alzheimer's Disease (AD) that is correlated with disease pathology and severity [1]. There has been limited progress in understanding of the vulnerability of this system, suggesting that there are other factors at play, such as ...
Marla A. Frick, Jennifer L. Woodruff, Yair M. Caudillo, Christian D. Wohlfeld, Claudia A. Grillo, Lawrence P. Reagan, Jim R. Fadel   +6 more
wiley   +1 more source

Synthesis, In Silico, and Biological Evaluation of Non‐Hydroxamate Benzoic Acid–Based Derivatives as Potential Histone Deacetylase Inhibitors (HDACi)

Chemistry &Biodiversity, Volume 22, Issue 12, December 2025.
Compound A3bn exhibited strong binding affinities for HDAC2, HDAC6, and HDAC8. A3bn’s anticancer IC50 values were similar to those of SAHA. Cell death resulted from the extrinsic apoptotic pathway. Compound A3bn, a hydrophilic linker, which promotes zinc coordination, may be the cause of its increased activity across HDAC isoforms. ABSTRACT Unregulated
Nedaa A. Abd Al Rahim, Ammar A. Razzak Mahmood, Lubna H. Tahtamouni, Randa M. Bawadi, Ayah Y. Almasri, Marya A. Hamad, Nour A. Hussein, Salem R. Yasin, Abdulrahman M. Saleh   +8 more
wiley   +1 more source