Results 51 to 60 of about 268,834 (305)

EDTA‐Functionalized Nanoscale Metal–Organic Framework for Onco‐Cardiology via Radiochemotherapy Synergy and Spatiotemporally Matched Iron Chelation

Advanced Science, EarlyView.
Doxorubicin (DOX)‐induced cardiotoxicity is a major limitation to its broader clinical application, while cardioprotective interventions often risk reducing the anticancer efficacy of DOX. To address these challenges, this work constructs an EDTA‐functionalized metal–organic framework that enhances tumor therapy and provides efficient cardioprotection ...
Daojing Yuan, Liyang Tian, Luwen Zhuang, Yongyu Liang, Lingfei Chen, Xuetao Wang, Yanli Li, Xiyong Yu, Teng Gong   +8 more
wiley   +1 more source

Fundraising Central: Majority of Presidential Bundlers and Other Fundraisers Hail from Only Five U.S. Industries: Lawyers and Law Firms, Three Finance Industries and Real Estate [PDF]

, 2007
More than half the major fundraisers for the presidential campaigns hail from just three segments of the U.S. economy: lawyers and law firms, representing both corporate and consumer interests; the financial sector; and real estate, according to a joint ...
Steve Weissman, Taylor Lincoln
core  

Bacterial Outer Membrane Vesicles in Potentiating Cancer Vaccines: Progress and Prospects

Advanced Science, EarlyView.
Bacterial outer membrane vesicles (OMVs) have emerged as versatile platforms for cancer vaccine development owing to their intrinsic immunostimulatory properties and high engineering flexibility. This review summarizes OMV biology, immune mechanisms, and engineering strategies that enhance vaccine efficacy, discusses key translational challenges, and ...
Jiabeini Zhang, Tianyu Shao, Fengjiang Qu, Caiyun Bai, Sijie Li, Pin Gao, Wenna Li, Keman Cheng, Xiao Zhao, Zhimin Fan   +9 more
wiley   +1 more source

Improved Real‐Time Hail Damage Estimates Leveraging Dense Crowdsourced Observations

Meteorological Applications
Severe hail storms are a leading cause of building damages in Switzerland, yet accurately observing hail using weather radar remains challenging. Opportunely, Switzerland benefits from a uniquely dense network of crowdsourced hail reports, providing an ...
Timo Schmid, Valentin Gebhart, David N. Bresch   +2 more
doaj   +1 more source

Effects of Different Materials and Structures on Mechanical Properties of Hail Used in Aviation Testing

Aerospace
Hail absorption test of aeroengine is one of the important components of airworthiness certification. The accurate test data are closely related to the density and mechanical properties of the artificial hail used in airworthiness tests.
Yewei Liu, Lifen Zhang, Xin Ge, Zhenxia Liu   +3 more
doaj   +1 more source

Hail, Trombones and Liszt [PDF]

, 2006
As the music department moved into its new digs in the Vivian A. Bull Music Center, musicians carried with them more than just instruments, sheet music and tuning forks.
Davis, Laura, Linfield Magazine Staff
core   +1 more source

ALKBH3 m1A Demethylase Deficiency Reduces Alzheimer's Amyloid‐β Pathology

Advanced Science, EarlyView.
This study identifies that ALKBH3‐driven m1A demethylation orchestrates Alzheimer's disease progression by disrupting mitochondrial and synaptic homeostasis. This epitranscriptomic mechanism suppresses PINK1‐mediated mitophagy via m1A erasure, leading to mitochondrial dysfunction, oxidative stress, elevated Aβ production, and impaired microglial ...
Yueyang Li, Sifei Yu, Kaidong Lu, Yujie Zhang, Mingjie Dong, Yan Peng, Liang Xue, Waleed Alam, Yuxuan Shui, Yi Zhou, Wuyunhan Ma, Meng Bao, Peiming Li, Peiyi Luo, Tiezhan Lu, Jiajia Li, Kang Zhang, Yuying Wang, Shuchen Yang, Nuoya Yin, Francesco Faiola, Zilong Gao, Jingfeng Zhou, Fei Zhao, Yali He, Magdalena J. Koziol   +25 more
wiley   +1 more source

HAIL SENSITIVE AREAS IN THE REPUBLIC OF MOLDOVA [PDF]

Scientific Papers Series : Management, Economic Engineering in Agriculture and Rural Development, 2016
In this study, the geographical and local topographic factors have been incorporated into geo-statistical approaches and also various models have been developed relating hail events to site position to assess of a hail hazard at high resolution in the ...
Mihail DARADUR, Tamara LEAH, Rajendra P. PANDEY, Valeriu CAZAC   +3 more
doaj  

Reconstructing hail days in Switzerland with statistical models (1959–2022) [PDF]

Natural Hazards and Earth System Sciences
Hail is one of the costliest natural hazards in Switzerland and causes extensive damage to agriculture, cars, and infrastructure each year. In a warming climate, hail frequency and its patterns of occurrence are expected to change, which is why ...
L. Wilhelm, C. Schwierz, K. Schröer, M. Taszarek, O. Martius   +4 more
doaj   +1 more source

Multi‐Tissue Omics Analysis Uncovers Translational Regulation Underlying Complex Traits in Pigs

Advanced Science, EarlyView.
Integrated multi‐omics across pig breeds and tissues reveals key principles of post‐transcriptional translational regulation and their contribution to trait formation. A gene network framework integrating transcriptomic and translatomic data is developed and applied to elucidate the genetic basis of meat production, offering new insights into mammalian
Chao Wang, Yuanyuan Zhang, Choulin Chen, Xiaoxian Xu, Shenghua Qin, Junyan Qi, Yongzhou Bao, Huiming Li, Ruipu Chen, Weigang Zheng, Zhilong Chen, Lingzhao Fang, Yunxiang Zhao, Yuwen Liu   +13 more
wiley   +1 more source