Results 171 to 180 of about 449,015 (299)

Breathing the Job: Impaired Pulmonary Function in Hairdressers due to Occupational Chemical Exposure. [PDF]

Med Lav
Demir Giden Z, Demir E, Giden R, Sevinç Akın HY.   +3 more
europepmc   +1 more source

Sensory Nerve‐Derived CGRP Controls Osteoclastogenesis by Limiting Macrophage Bioenergetics in Bone Repair

Advanced Science, EarlyView.
Sensory nerves help bones heal. This study shows that the neuropeptide CGRP, released from sensory nerves, slows down macrophage energy production, preventing excessive bone breakdown. By revealing this nerve–immune–metabolism connection, the work provides new insight into how the body balances bone repair and opens doors to targeted treatments ...
Jiaying Liu, Ting Zhang, Yuqing Mu, Lili Li, Ju Jin, Kevin J Dudley, Wendong Gao, Donglin Cai, Fuhua Yan, Lan Xiao, Yin Xiao   +10 more
wiley   +1 more source

Female pattern hair loss. [PDF]

CMAJ
McMullen E, Aldien AS, Sibbald C, Donovan J.   +3 more
europepmc   +1 more source

Congenital Hypotrichosis in a female Rottweiler [PDF]

, 1993
Ihrke, P. J., Mueller, Ralf S., Stannard, A. A.   +2 more
core   +1 more source

The Transcription Factor FgSge1 Harnesses the SAGA Complex to Activate Mycotoxin Biosynthesis and Fungal Virulence

Advanced Science, EarlyView.
This study reveals the molecular mechanism by which the transcription factor FgSge1 regulates mycotoxin biosynthesis and virulence in Fusarium graminearum. FgSge1 binds to the TAARGTTT cis‐element, enabling self‐activation. It recruits the SAGA complex, promotes histone acetylation, and facilitates jet‐like chromatin remodeling, thereby activating ...
Yueqi Zhang, Jingrui Wang, Qiaowan Chen, Chen Jiao, Yun Chen, Zhongshou Wu, Zhonghua Ma   +6 more
wiley   +1 more source

Natural products and their derivatives as candidate treatments for hair greying: from drug discovery to molecular mechanisms. [PDF]

Chin Med
Zhu C, Gao Y, Gong H, Wang J.
europepmc   +1 more source

Genetic Diagnosis and Discovery Enabled by Large Language Models

Advanced Science, EarlyView.
We demonstrate that large language models (LLMs) can facilitate genetic diagnosis and discovery. LLMs were used to solve four types of genetic problems of sequentially increased complexity. An LLM‐based pipeline could analyze genetic variants in the genomic sequences of human hearing loss or rare genetic disease patients and assist in identifying ...
Tao Tu, Khaled Saab, Weida Liu, Zhouqing Fang, Zhuanfen Cheng, Svetolik Spasic, Maja Djurisic, Hiroaki Mohri, Wenlong Ren, Anil Palepu, Juraj Gottweis, Alan Karthikesalingam, Kavita Kulkarni, Annalisa Pawlosky, Devon Bonner, Elijah Kravets, Shruti Marwaha, Hector R. Mendez, Matthew T. Wheeler, Jonathan A. Bernstein, Undiagnosed Diseases Network, Cheng‐Yu Tsai, Chen‐Chi Wu, Konstantina M. Stankovic, Vivek Natarajan, Gary Peltz   +25 more
wiley   +1 more source

PrEP and Contraceptive Persistence Among Young Women Receiving Sexual and Reproductive Health Services Through Hair Salons in South Africa. [PDF]

J Acquir Immune Defic Syndr
Bassett IV, Yan J, Govere S, Johnson LS, Shezi S, Ngcobo LM, Sagar S, Sagar S, Jarolimova J, Zionts D, Khumalo A, Zwane PG, Dube N, Psaros C, Parker RA.   +14 more
europepmc   +1 more source

Nanotherapeutic Macrophage‐Neuro Reprogramming Through Immunometabolic Crosstalk Mitigates Sepsis‐Induced Lung Injury and Neurologic Damage

Advanced Science, EarlyView.
SJNPs co‐deliver JHU083 and spermine to reprogram macrophage–neuron immunometabolic crosstalk in sepsis. By suppressing pro‐inflammatory M1 polarization and promoting NGF‐mediated neurotrophic signaling, SJNPs preserve pulmonary neuronal integrity, alleviate lung injury, and improve survival in murine sepsis models.
Wenhui Wang, Yongrui Hai, Xintong Lu, Ye Chen, Bingjie Zhang, Renming Fan, Jiarui Dou, Jiaxin Yan, Shuo Fu, Wen Zhang, Junke Song, Gaofei Wei   +11 more
wiley   +1 more source

Cutaneous Manifestations of Inborn Errors of Immunity: Clinical Clues to Immune Disorders. [PDF]

Medicina (Kaunas)
Napiorkowska-Baran K, Pastuszczak M, Płocka-Karpińska M, Tykwińska M, Treichel P, Margossian GA, Margossian CL, Rogalska A, Czajkowski R.   +8 more
europepmc   +1 more source