Results 51 to 60 of about 449,015 (299)

Yellow dots in trichoscopy: relevance, clinical significance and peculiarities [PDF]

Anais Brasileiros de Dermatologia, 2017
: Yellow dots are follicular ostium filled with keratin and/or sebum. Initially, they were exclusively associated with alopecia areata. Currently they have also been described in androgenetic alopecia, chronic cutaneous (discoid) lupus erythematosus, and
Caren dos Santos Lima, Luciana Rodino Lemes, Daniel Fernandes Melo   +2 more
doaj   +2 more sources

Morphogenesis, Growth Cycle and Molecular Regulation of Hair Follicles

Frontiers in Cell and Developmental Biology, 2022
As one of the main appendages of skin, hair follicles play an important role in the process of skin regeneration. Hair follicle is a tiny organ formed by the interaction between epidermis and dermis, which has complex and fine structure and periodic ...
Xiangyu Lin, Liang Zhu, Jing He
doaj   +1 more source

Spaceflight modulates gene expression in the whole blood of astronauts [PDF]

, 2016
Astronauts are exposed to a unique combination of stressors during spaceflight, which leads to alterations in their physiology and potentially increases their susceptibility to disease, including infectious diseases.
Barrila, Jennifer, Crabbé, Aurélie, LeBlanc, Carly, Mehta, Satish K, Nickerson, Cheryl A, Ott, C Mark, Pierson, Duane L, Stafford, Phillip   +7 more
core   +2 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

A prospective descriptive study of 100 patients with facial trichostasis spinulosa

Turkderm Turkish Archives of Dermatology and Venereology
Background and Design: Trichostasis spinulosa (TS) is a common but frequently underdiagnosed dermatological condition. Dermoscopy has recently been identified as the most practical and useful noninvasive diagnostic tool.
Ecem Baklan, Ayda Acar, Işıl Karaarslan, İdil Ünal   +3 more
doaj   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Numerical simulation of the hair formation –modeling of hair cycle [PDF]

, 2018
In the recent years, the fields of study of anti-aging, health and beauty, cosmetics, and hair diseases have attracted significant attention. In particular, human hair is considered to be an important aspect with regard to an attractive appearance.
Kajihara Narumichi, Nagayama Katsuya
core   +2 more sources

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Hair microscopy: an easy adjunct to diagnosis of systemic diseases in children

Applied Microscopy, 2021
Hair, having distinct stages of growth, is a dynamic component of the integumentary system. Nonetheless, derangement in its structure and growth pattern often provides vital clues for the diagnosis of systemic diseases.
Dharmagat Bhattarai, Aaqib Zaffar Banday, Rohit Sadanand, Kanika Arora, Gurjit Kaur, Satish Sharma, Amit Rawat   +6 more
doaj   +1 more source