Hair Graying Regulators Beyond Hair Follicle [PDF]
Frontiers in Physiology, 2022 Hair graying is an interesting physiological alteration associated with aging and certain diseases. The occurrence is due to depigmentation of the hair caused by depletion and dysfunction of melanocyte stem cells (MeSCs).
Jing Chen +8 more
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Emerging biomedical engineering strategies for hair follicle regeneration [PDF]
Bioactive MaterialsHair follicle undergoes cyclical regeneration that relies on the spatiotemporal coordination of epithelial-mesenchymal interactions and multiple signaling pathways. However, hair follicle homeostasis is susceptible to disruption by various endogenous and
Xinyue Cao +5 more
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MCL‑1 safeguards activated hair follicle stem cells to enable adult hair regeneration [PDF]
Nature CommunicationsHair follicles cycle through expansion, regression and quiescence. To investigate the role of MCL‑1, a BCL‑2 family protein with anti‑apoptotic and apoptosis‑unrelated functions, we delete Mcl‑1 within the skin epithelium using constitutive and inducible
Hui San Chin +19 more
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Circ 0020938 inhibits hair follicle stem cells proliferation via the miR-142-5p/DSG4 axis in cashmere goats [PDF]
BMC GenomicsBackground Shaanbei white cashmere goat is an excellent cashmere goat breed, and its market favored cashmere from the secondary hair follicles. Hair follicles mature around birth and each hair follicle repeatedly undergoes a growth cycle that comprises ...
Jiamian Du +5 more
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Progress on mitochondria and hair follicle development in androgenetic alopecia: relationships and therapeutic perspectives [PDF]
Stem Cell Research & TherapyHair loss has long been a significant concern for many individuals. Recent studies have indicated that mitochondria play a more crucial role in hair loss than previously recognized.
Ting-ru Dong +7 more
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Platelet-rich plasma-derived exosomes stimulate hair follicle growth through activation of the Wnt/β-Catenin signaling pathway [PDF]
Regenerative TherapyBackground: Androgenetic alopecia (AGA) is a common type of hair loss that affects a large segment of the global population, significantly influencing individuals' appearance and mental health.
Changpei Lu +9 more
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Induction of Hair Follicle Growth
Journal of Investigative Dermatology, 1991 Kurt S. Stenn
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Wls is expressed in the epidermis and regulates embryonic hair follicle induction in mice. [PDF]
PLoS ONE, 2012 Wnt proteins are secreted molecules that play multiple roles during hair follicle development and postnatal hair cycling. Wntless (Wls) is a cargo protein required for the secretion of various Wnt ligands.
Sixia Huang +7 more
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International Journal of Dermatology, 1992 AbstractFour cases of hair follicle nevi are described. Hair follicle nevus is an extremely rare hamartoma occurring on the face, which has had no clear histopathologic definition until now. A short review of the clinicopathologic features of this disease is presented.
Eung Ho Choi +3 more
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Hair Follicle Pigmentation [PDF]
Journal of Investigative Dermatology, 2005 Hair shaft melanin components (eu- or/and pheomelanin) are a long-lived record of precise interactions in the hair follicle pigmentary unit, e.g., between follicular melanocytes, keratinocytes, and dermal papilla fibroblasts. Follicular melanogenesis (FM) involves sequentially the melanogenic activity of follicular melanocytes, the transfer of melanin ...
Ralf Paus +6 more
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