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Hair Graying Regulators Beyond Hair Follicle [PDF]

open access: yesFrontiers in Physiology, 2022
Hair graying is an interesting physiological alteration associated with aging and certain diseases. The occurrence is due to depigmentation of the hair caused by depletion and dysfunction of melanocyte stem cells (MeSCs).
Jing Chen   +8 more
doaj   +3 more sources

Functional hair follicle regeneration: an updated review

open access: yesSignal Transduction and Targeted Therapy, 2021
The hair follicle (HF) is a highly conserved sensory organ associated with the immune response against pathogens, thermoregulation, sebum production, angiogenesis, neurogenesis and wound healing. Although recent advances in lineage-tracing techniques and
Xiaobing Fu
exaly   +2 more sources

Integrative Analysis of Methylome and Transcriptome Reveals the Regulatory Mechanisms of Hair Follicle Morphogenesis in Cashmere Goat

open access: yesCells, 2020
Studies in humans and mice have revealed that hair follicle morphogenesis relies on tightly coordinated ectodermal–mesodermal interactions, involving multiple signals and regulatory factors.
Shanhe Wang   +7 more
doaj   +2 more sources

Hair Follicle [PDF]

open access: yesDefinitions, 2020
A tube-like invagination of the epidermis from which the hair shaft develops and into which the sebaceous glands open; the follicle is lined by a cellular inner and outer root sheath of epidermal origin and is invested with a fibrous sheath derived from ...
openaire   +2 more sources

Emerging biomedical engineering strategies for hair follicle regeneration [PDF]

open access: yesBioactive Materials
Hair follicle undergoes cyclical regeneration that relies on the spatiotemporal coordination of epithelial-mesenchymal interactions and multiple signaling pathways. However, hair follicle homeostasis is susceptible to disruption by various endogenous and
Xinyue Cao   +5 more
doaj   +2 more sources

Synergizing biomaterials and cellular molecular pathways: a new frontier in hair follicle generation [PDF]

open access: yesJournal of Translational Medicine
Despite significant advances in our understanding of hair follicle cycling and regeneration, creating fully functional hair follicles with active cycling capabilities remains a considerable challenge for clinical applications. This literature review aims
Amir Bajouri   +2 more
doaj   +2 more sources

The Skin Microenvironment: A Dynamic Regulator of Hair Follicle Development, Cycling and Disease [PDF]

open access: yesBiomolecules
As essential skin appendages, hair follicles exhibit complex developmental and regenerative processes shaped by the skin microenvironment. Imbalances in skin microenvironmental homeostasis are often accompanied by follicle miniaturization and even hair ...
Weiguo Song   +6 more
doaj   +2 more sources

Human Hair and the Impact of Cosmetic Procedures: A Review on Cleansing and Shape-Modulating Cosmetics [PDF]

open access: yesCosmetics, 2016
Hair can be strategically divided into two distinct parts: the hair follicle, deeply buried in the skin, and the visible hair fiber. The study of the hair follicle is mainly addressed by biological sciences while the hair fiber is mainly studied from a ...
Célia F. Cruz   +4 more
doaj   +3 more sources

The hair follicle enigma [PDF]

open access: yesExperimental Dermatology, 2017
AbstractThe hair follicle is a mini‐organ endowed with a unique structure and cyclic behaviour. Despite the intense research efforts which have been devoted at deciphering the hair follicle biology over the past 70 years, one must admit that hair follicle remains an enigma.
B. Bernard
openaire   +3 more sources

Tissue engineering strategies for human hair follicle regeneration: How far from a hairy goal?

open access: yesStem Cells Translational Medicine, 2020
The demand for an efficient therapy for alopecia disease has fueled the hair research field in recent decades. However, despite significant improvements in the knowledge of key processes of hair follicle biology such as genesis and cycling, translation ...
Ana Rita Castro, Elsa Logarinho
doaj   +2 more sources

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