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Hair Graying Regulators Beyond Hair Follicle [PDF]
Frontiers in Physiology, 2022 Hair graying is an interesting physiological alteration associated with aging and certain diseases. The occurrence is due to depigmentation of the hair caused by depletion and dysfunction of melanocyte stem cells (MeSCs).
Jing Chen +8 more
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Emerging biomedical engineering strategies for hair follicle regeneration [PDF]
Bioactive MaterialsHair follicle undergoes cyclical regeneration that relies on the spatiotemporal coordination of epithelial-mesenchymal interactions and multiple signaling pathways. However, hair follicle homeostasis is susceptible to disruption by various endogenous and
Xinyue Cao +5 more
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The Skin Microenvironment: A Dynamic Regulator of Hair Follicle Development, Cycling and Disease [PDF]
BiomoleculesAs essential skin appendages, hair follicles exhibit complex developmental and regenerative processes shaped by the skin microenvironment. Imbalances in skin microenvironmental homeostasis are often accompanied by follicle miniaturization and even hair ...
Weiguo Song +6 more
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MCL‑1 safeguards activated hair follicle stem cells to enable adult hair regeneration [PDF]
Nature CommunicationsHair follicles cycle through expansion, regression and quiescence. To investigate the role of MCL‑1, a BCL‑2 family protein with anti‑apoptotic and apoptosis‑unrelated functions, we delete Mcl‑1 within the skin epithelium using constitutive and inducible
Hui San Chin +19 more
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Progress on mitochondria and hair follicle development in androgenetic alopecia: relationships and therapeutic perspectives [PDF]
Stem Cell Research & TherapyHair loss has long been a significant concern for many individuals. Recent studies have indicated that mitochondria play a more crucial role in hair loss than previously recognized.
Ting-ru Dong +7 more
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Induction of Hair Follicle Growth
Journal of Investigative Dermatology, 1991 Kurt S. Stenn
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International Journal of Dermatology, 1992 AbstractFour cases of hair follicle nevi are described. Hair follicle nevus is an extremely rare hamartoma occurring on the face, which has had no clear histopathologic definition until now. A short review of the clinicopathologic features of this disease is presented.
Eung Ho Choi +3 more
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Wls is expressed in the epidermis and regulates embryonic hair follicle induction in mice. [PDF]
PLoS ONE, 2012 Wnt proteins are secreted molecules that play multiple roles during hair follicle development and postnatal hair cycling. Wntless (Wls) is a cargo protein required for the secretion of various Wnt ligands.
Sixia Huang +7 more
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Hair Follicle Pigmentation [PDF]
Journal of Investigative Dermatology, 2005 Hair shaft melanin components (eu- or/and pheomelanin) are a long-lived record of precise interactions in the hair follicle pigmentary unit, e.g., between follicular melanocytes, keratinocytes, and dermal papilla fibroblasts. Follicular melanogenesis (FM) involves sequentially the melanogenic activity of follicular melanocytes, the transfer of melanin ...
Ralf Paus +6 more
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Apoptosis in the Hair Follicle [PDF]
Journal of Investigative Dermatology, 2006 Apoptosis plays an important role in many physiological processes, ranging from morphogenetic events to adult tissue homeostasis, and defects in its regulation contribute to many disorders. Here we review molecular mechanisms of apoptosis in the hair follicle (HF), whose cyclical growth pattern is repeatedly interrupted by apoptosis-driven involution ...
Douglas Shander +2 more
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