Results 1 to 10 of about 47,932 (261)

Synergizing biomaterials and cellular molecular pathways: a new frontier in hair follicle generation [PDF]

Journal of Translational Medicine
Despite significant advances in our understanding of hair follicle cycling and regeneration, creating fully functional hair follicles with active cycling capabilities remains a considerable challenge for clinical applications. This literature review aims
Amir Bajouri, Nasser Aghdami, Mohammad Ali Nilforoushzadeh   +2 more
doaj   +2 more sources

Emerging biomedical engineering strategies for hair follicle regeneration [PDF]

Bioactive Materials
Hair follicle undergoes cyclical regeneration that relies on the spatiotemporal coordination of epithelial-mesenchymal interactions and multiple signaling pathways. However, hair follicle homeostasis is susceptible to disruption by various endogenous and
Xinyue Cao, Minhui Lu, Ning Li, Lijun Cai, Yu Wang, Yuanjin Zhao   +5 more
doaj   +2 more sources

The Skin Microenvironment: A Dynamic Regulator of Hair Follicle Development, Cycling and Disease [PDF]

Biomolecules
As essential skin appendages, hair follicles exhibit complex developmental and regenerative processes shaped by the skin microenvironment. Imbalances in skin microenvironmental homeostasis are often accompanied by follicle miniaturization and even hair ...
Weiguo Song, Mingli Peng, Qiqi Ma, Xiaoyu Han, Chunyan Gao, Wenqi Zhang, Dongjun Liu   +6 more
doaj   +2 more sources

Scalp Apocrine Glands: The Neglected Component of the Hair Follicle Complex. [PDF]

Skin Appendage Disord
Torres FN, Donda ALV, Melo DF.
europepmc   +3 more sources

Hair Graying Regulators Beyond Hair Follicle

Frontiers in Physiology, 2022
Hair graying is an interesting physiological alteration associated with aging and certain diseases. The occurrence is due to depigmentation of the hair caused by depletion and dysfunction of melanocyte stem cells (MeSCs).
Jing Chen, Jing Chen, Yixin Zheng, Chen Hu, Xuexiao Jin, Xiaoping Chen, Ying Xiao, Chaochen Wang, Chaochen Wang   +8 more
doaj   +1 more source

Wls is expressed in the epidermis and regulates embryonic hair follicle induction in mice. [PDF]

PLoS ONE, 2012
Wnt proteins are secreted molecules that play multiple roles during hair follicle development and postnatal hair cycling. Wntless (Wls) is a cargo protein required for the secretion of various Wnt ligands.
Sixia Huang, Xuming Zhu, Yanfang Liu, Yixin Tao, Guoyin Feng, Lin He, Xizhi Guo, Gang Ma   +7 more
doaj   +1 more source

Identification of N6-Methyladenosine-Related Factors and the Prediction of the Regulatory Mechanism of Hair Follicle Development in Rex and Hycole Rabbits

Biology, 2023
Hair follicle development directly affects the development of the rabbit fur industry. The growth and development of a hair follicle is modified and regulated by many genes and mechanisms. M6A is an important RNA modification.
Gang Luo, Ruiguang Gong, Yaotian Ai, Tongyan Zhu, Zhanjun Ren   +4 more
doaj   +1 more source

Gene network analysis reveals candidate genes related with the hair follicle development in sheep

BMC Genomics, 2022
Background Merino sheep are the most famous fine wool sheep in the world. They have high wool production and excellent wool quality and have attracted worldwide attention. The fleece of the Merino sheep is composed predominantly of wool fibers grown from
Junmin He, Bingru Zhao, Xixia Huang, Xuefeng Fu, Guifen Liu, Yuezhen Tian, Cuiling Wu, Jingyi Mao, Jing Liu, Shuangbao Gun, Kechuan Tian   +10 more
doaj   +1 more source

Hair follicle-targeting drug delivery strategies for the management of hair follicle-associated disorders

Asian Journal of Pharmaceutical Sciences, 2022
The hair follicle is not only a critical penetration route in percutaneous absorption but also has been recognized to be a target for hair follicle-associated disorders, such as androgenetic alopecia (AGA) and acne vulgaris.
Yueting Gu, Qiong Bian, Yanjun Zhou, Qiaoling Huang, Jianqing Gao   +4 more
doaj   +1 more source

Integrative Analysis of Methylome and Transcriptome Reveals the Regulatory Mechanisms of Hair Follicle Morphogenesis in Cashmere Goat

Cells, 2020
Studies in humans and mice have revealed that hair follicle morphogenesis relies on tightly coordinated ectodermal–mesodermal interactions, involving multiple signals and regulatory factors.
Shanhe Wang, Fang Li, Jinwang Liu, Yuelang Zhang, Yujie Zheng, Wei Ge, Lei Qu, Xin Wang   +7 more
doaj   +1 more source