Results 11 to 20 of about 47,932 (261)

Novel recombinant R-spondin1 promotes hair regeneration by targeting the Wnt/β-catenin signaling pathway

Acta Biochimica et Biophysica Sinica, 2023
Roof plate-specific spondin 1 (R-spondin1, RSPO1) is a Wnt/β-catenin signaling pathway activator that binds with Wnt ligands to stimulate the Wnt/β-catenin signaling pathway, which is key to hair regeneration. However, it is not clear whether recombinant
Chen Yijun, Lu Zhujin, Feng Jiaxin, Chen Zefeng, Liu Zejian, Wang Xiuqi, Yan Huichao, Gao Chunqi   +7 more
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Hair follicle regional specificity in different parts of bay Mongolian horse by histology and transcriptional profiling

BMC Genomics, 2020
Background Different morphological structures of hairs having properties like defense and camouflage help animals survive in the wild environment.
Ruoyang Zhao, Wu Yihan, Yiping Zhao, Bei Li, Haige Han, Togtokh Mongke, Tugeqin Bao, Wenxing Wang, Manglai Dugarjaviin, Dongyi Bai   +9 more
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LGR5 is a conserved marker of hair follicle stem cells in multiple species and is present early and throughout follicle morphogenesis

Scientific Reports, 2022
Hair follicle stem cells are key for driving growth and homeostasis of the hair follicle niche, have remarkable regenerative capacity throughout hair cycling, and display fate plasticity during cutaneous wound healing.
Kathryn M. Polkoff, Nithin K. Gupta, Adrian J. Green, Yanet Murphy, Jaewook Chung, Katherine L. Gleason, Sean G. Simpson, Derek M. Walker, Bruce Collins, Jorge A. Piedrahita   +9 more
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Expression profile of long non-coding RNA in inner Mongolian cashmere goat with putative roles in hair follicles development

Frontiers in Veterinary Science, 2022
The hair follicle is a complex skin accessory organ, which determines hair growth. Long non-coding RNAs (lncRNAs) have been proven to play an important role in hair follicle development, but their specific mechanism is still unclear.
Rong Ma, Fangzheng Shang, Youjun Rong, Jianfeng Pan, Min Wang, Shuran Niu, Yunpeng Qi, Yanbo Li, Qi Lv, Zhiying Wang, Ruijun Wang, Rui Su, Zhihong Liu, Yanhong Zhao, Zhixin Wang, Jinquan Li, Jinquan Li, Jinquan Li, Yanjun Zhang   +18 more
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Advances in Understanding Hair Growth [version 1; referees: 2 approved]

F1000Research, 2016
In this short review, I introduce an integrated vision of human hair follicle behavior and describe opposing influences that control hair follicle homeostasis, from morphogenesis to hair cycling.
Bruno A. Bernard
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Autoantigen Discovery in the Hair Loss Disorder, Alopecia Areata: Implication of Post-Translational Modifications

Frontiers in Immunology, 2022
Alopecia areata (AA) is a chronic, multifactorial, polygenic, and heterogeneous disorder affecting growing hair follicles in susceptible individuals, which results in a non-scarring and reversible hair loss with a highly unpredictable course.
Shahnawaz D. Jadeja, Desmond J. Tobin, Desmond J. Tobin   +2 more
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Pre-aggregation of scalp progenitor dermal and epidermal stem cells activates the WNT pathway and promotes hair follicle formation in in vitro and in vivo systems

Stem Cell Research & Therapy, 2019
Background Billions of dollars are invested annually by pharmaceutical companies in search of new options for treating hair loss conditions; nevertheless, the challenge remains.
Yiqun Su, Jie Wen, Junrong Zhu, Zhiwei Xie, Chang Liu, Chuan Ma, Qun Zhang, Xin Xu, Xunwei Wu   +8 more
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Ginsenoside CK inhibits androgenetic alopecia by regulating Wnt/β‐catenin and p53 signaling pathways in AGA mice

Food Frontiers, 2023
Androgenetic alopecia (AGA) is one of the most common chronic skin diseases caused by the destruction of androgens in the body. It is caused by the excessive deposition of dihydrotestosterone around the hair follicle, resulting in hair follicle atrophy ...
Chao Fang, Haixia Yang, Chenhui Zhu, Daidi Fan, Jianjun Deng   +4 more
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Bioengineering of Hair Follicle-like Structure for Validation of Hair Growth Promoting Compounds

Bioengineering, 2022
We aimed to establish screening and efficacy test techniques for use in the development of hair-promoting agents. To this end, we used the dermal papilla cell (DPc)-derived immortalized cell line (SV40T-hTERT DPc) and neonatal foreskin-derived ...
Hyun Woo Joo, Min Kyu Kim, Soon Sun Bak, Young Kwan Sung   +3 more
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Re-activation of Wnt/β-catenin Signaling Pathway in Hair Follicle Stem Cells in Treatment of Androgenetic Alopecia

Journal of Mazandaran University of Medical Sciences, 2022
Hair loss is a common hair disorder in human population. It affects quality of life and there are ongoing attempts to find permanent treatment for this condition. But, today there is no completely safe and protective treatment for all. Hair follicle stem
Razieh Zarei, Majid Saeedi, Ali Hosseinzade   +2 more
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