Results 311 to 320 of about 846,397 (361)

CCDC80 Protects against Aortic Dissection and Rupture by Maintaining the Contractile Smooth Muscle Cell Phenotype

open access: yesAdvanced Science, EarlyView.
Aortic dissection (AD) is accompanied by a decrease in CCDC80 in vascular smooth muscle cells (VSMCs). CCDC80 can interact with JAK2, and VSMC‐specific CCDC80 deficiency accelerates the progression of AD by activating the JAK2/STAT3 pathway involved in regulating the phenotype switching and function of VSMCs.
Qingqing Xiao   +18 more
wiley   +1 more source

The Hormonal Background of Hair Loss in Non-Scarring Alopecias. [PDF]

open access: yesBiomedicines
Owecka B   +3 more
europepmc   +1 more source

Nano‐Oil‐Barrier‐Based Fluttering Triboelectric Nanogenerator

open access: yesAdvanced Science, EarlyView.
This work proposes a wind‐driven nano‐oil‐barrier‐based fluttering triboelectric nanogenerator (NF‐TENG). A nano‐oil barrier is a simple and innovative strategy to maintain a thin lubricant layer for long‐term cycling based on commercial oil‐absorbing sheets and oil‐infusion steps, which can improve both mechanical and electrical stability of TENGs ...
Deokjae Heo   +8 more
wiley   +1 more source

Kinsenoside‐Loaded Microneedle Accelerates Diabetic Wound Healing by Reprogramming Macrophage Metabolism via Inhibiting IRE1α/XBP1 Signaling Axis

open access: yesAdvanced Science, EarlyView.
Gut metabolite trimethylamine N‐oxide accumulates in the diabetic wound area to amplify macrophage inflammation via enhancing glycolysis activities. Kinsenoside induces macrophage repolarization from M1 to M2 phenotype through inhibiting IRE1α/XBP1 pathway, followed by HIF‐1α‐glycolysis axis repression and mitophagy‐oxidative phosphorylation axis ...
Li Lu   +13 more
wiley   +1 more source

ADAM17 variant causes hair loss via ubiquitin ligase TRIM47-mediated degradation. [PDF]

open access: yesJCI Insight
Wang X   +15 more
europepmc   +1 more source

Amino Acid‐Sensing Neurons in the Anterior Piriform Cortex Control Brown Adipose Tissue Thermogenesis

open access: yesAdvanced Science, EarlyView.
This study identifies a class of amino acid‐sensing neurons, APCCRH neurons, which regulate BAT thermogenesis. Leucine deficiency alters intrinsic excitability through GCN2 signaling pathway, activating APCCRH neurons, which in turn regulate BAT thermogenesis via projections to the lateral hypothalamus.
Peixiang Luo   +15 more
wiley   +1 more source

Lupus Panniculitis With Linear Hair Loss on the Scalp. [PDF]

open access: yesDermatol Pract Concept
Chou YJ, Ko PH, Wang KH, Chang HC.
europepmc   +1 more source

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