Results 41 to 50 of about 199,686 (265)
Acta Dermato-Venereologica, 2020 is missing (Short communication)
Florentia Dimitriou +2 more
doaj +1 more source
Effects of taxifolin from enzymatic hydrolysis of Rhododendron mucrotulatum on hair growth promotion
Frontiers in Bioengineering and Biotechnology, 2022 Flavonoid aglycones possess biological activities, such as antioxidant and antidiabetic activities compared to glycosides. Taxifolin, a flavonoid aglycones, is detected only in trace amounts in nature and is not easily observed. Therefore, in this study,
Sun-Min Park +10 more
doaj +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Hormonal therapy in female pattern hair loss
International Journal of Women's Dermatology, 2017 Female pattern hair loss is the most common cause of hair loss in women and one of the most common problems seen by dermatologists. This hair loss is a nonscarring alopecia in which loss occurs on the vertex scalp, generally sparing the frontal hairline.
Kevin R. Brough, Rochelle R. Torgerson
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Advanced medical treatments for hair loss
Cell TransplantationPatients with hair-loss experience stress and a loss of confidence. Several factors contribute to hair loss, including aging, androgen hormone effects, genetics, and diseases.
Kwanrudee Kaewmungkun +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Stimulation of Hair Growth by Small Molecules that Activate Autophagy
Cell Reports, 2019 Summary: Hair plays important roles, ranging from the conservation of body heat to the preservation of psychological well-being. Hair loss or alopecia affects millions worldwide, but methods that can be used to regrow hair are lacking.
Min Chai +12 more
doaj +1 more source
CXXC5 Mediates DHT-Induced Androgenetic Alopecia via PGD2
Cells, 2023 The number of people suffering from hair loss is increasing, and hair loss occurs not only in older men but also in women and young people. Prostaglandin D2 (PGD2) is a well-known alopecia inducer. However, the mechanism by which PGD2 induces alopecia is
Yeong Chan Ryu +10 more
doaj +1 more source