Results 11 to 20 of about 22,302 (228)

Classic Hairy Cell Leukemia With MAP2K1 Mutation: Diagnosis and Targeted Therapy. [PDF]

Am J Hematol
American Journal of Hematology, Volume 101, Issue 2, Page 339-340, February 2026.
Duminuco A, Venanzi A, Santi A, Mancini A, Romano A, Tiacci E.   +5 more
europepmc   +2 more sources

Selective influences in the expressed immunoglobulin heavy and light chain gene repertoire in hairy cell leukemia

Haematologica, 2008
Background We previously reported ongoing mutational and isotype switch events in the immunoglobulin (Ig) heavy chain (H) locus in hairy cell leukemia.
Francesco Forconi, Elisa Sozzi, Davide Rossi, Surinder S. Sahota, Teresa Amato, Donatella Raspadori, Livio Trentin, Lorenzo Leoncini, Gianluca Gaidano, Francesco Lauria   +9 more
doaj   +1 more source

Recent advances in understanding and managing hairy cell leukemia [version 1; referees: 4 approved]

F1000Research, 2018
Hairy cell leukemia is a rare B-cell malignancy that is characterized by an indolent course. It was initially described as a distinct entity in 1958. Before the establishment of modern treatment, median survival was only 4 years.
Tobias Roider, Brunangelo Falini, Sascha Dietrich   +2 more
doaj   +1 more source

Hairy cell leukemia with an aggressive outcome: A case report with a review of the literature

MGM Journal of Medical Sciences, 2023
Hairy cell leukemia (HCL), an uncommon cancer affecting B-lymphocytes primarily in the bone marrow and spleen, is identified by abnormal projections on malignant B cells, which give the illness its name.
Adwaita Mashelkarm, Shirish Khatu, Prakash Dive, S Sudhamani   +3 more
doaj   +1 more source

Neutropenia caused by hairy cell leukemia in a patient with myelofibrosis secondary to polycythemia vera: a case report

Journal of Medical Case Reports, 2018
Background Polycythemia vera is a myeloproliferative disease that sometimes evolves to myelofibrosis, causing splenomegaly and neutropenia. In this case report, we describe a patient with polycythemia vera and unexplained neutropenia who later turned out
Andreas Hanssønn Habberstad, Hoa Thi Tuyet Tran, Ulla Randen, Signe Spetalen, Ingunn Dybedal, Geir E. Tjønnfjord, Anders Erik Astrup Dahm   +6 more
doaj   +1 more source

A Hairy Cell Leukaemia Variant – A Rare Case Report [PDF]

Journal of Clinical and Diagnostic Research, 2013
The aim of the article is to present a rare case of Hairy cell leukaemia variant (HCl-V) which is a distinct clinico-pathological entity with intermediate features between classical HCl (HCl-C) and B-cell prolymphocytic leukaemia.
Pankaj Pande, Balasaheb Ramling Yelikar, Mahesh Kumar U   +2 more
doaj   +1 more source

Visszatérő szomatikus mutáció hajas sejtes leukémiában [PDF]

, 2013
A hajas sejtes leukémia olyan érett B-sejtes non-Hodgkin-lymphoma, amelyet egyedi klinikai, morfológiai és immunfenotípusbeli sajátosságok jellemeznek. A betegséget splenomegalia, progresszív pancytopenia és relatív indolens lefolyás kíséri.
Demeter, Judit, Nagy, Zsolt, Sári, Eszter   +2 more
core   +1 more source

Tuberculous (TB) Meningitis and Pneumonia in a Case of Hairy Cell Leukemia Treated by 2-CDA [PDF]

International Journal of Hematology-Oncology and Stem Cell Research, 2012
Patients with lymphoproliferative disorders have cellular immune deficiency and are susceptible to typical and atypical mycobacterial infections.Hairy cell leukemia is a B-cell type lymphoproliferative disorder.2-CDA is the choice of treatment for ...
Shahin Nateghi, Rahim Nejad Rahim, Nasim Valizadeh   +2 more
doaj   +2 more sources

Ibrutinib inhibits SDF1/CXCR4 mediated migration in AML [PDF]

, 2014
Pharmacological targeting of BTK using ibrutinib has recently shown encouraging clinical activity in a range of lymphoid malignancies. Recently we reported that ibrutinib inhibits human acute myeloid leukemia (AML) blast proliferation and leukemic cell ...
Bowles, Kristian M, Lawes, Matthew J, MacEwan, David J, Murray, Megan Y, Rushworth, Stuart A, Shafat, Manar S., Zaitseva, Lyubov   +6 more
core   +2 more sources

Detection of BRAF mutations in patients with hairy cell leukemia and related lymphoproliferative disorders

Haematologica, 2012
Hairy cell leukemia has been shown to be strongly associated with the BRAF V600E mutation. We screened 59 unenriched archived bone marrow aspirate and peripheral blood samples from 51 patients with hairy cell leukemia using high resolution melting ...
Piers A. Blombery, Stephen Q. Wong, Chelsee A. Hewitt, Alexander Dobrovic, Ellen L. Maxwell, Surender Juneja, George Grigoriadis, David A. Westerman   +7 more
doaj   +1 more source