Results 21 to 30 of about 22,302 (228)
Identification of Bruton's tyrosine kinase as a therapeutic target in acute myeloid leukemia [PDF]
, 2014 Bruton's tyrosine kinase (BTK) is a cytoplasmic protein found in all hematopoietic cell lineages except for T cells. BTK mediates signalling downstream of a number of receptors.
Advani +59 more
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Long-term follow-up after purine analogue therapy in hairy cell leukaemia [PDF]
, 2003 Since 2006 when we last reviewed the literature concerning the use of purine analogues in hairy cell leukaemia (HCL), results from several new and updated series have been published.
Else, Monica +2 more
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Hairy Cell Leukemia: the good news of a bad disease
Galicia Clínica, 2017 Hairy Cell Leukemia (HCL) is an uncommon chronic B cell Lymphoproliferative disorder characterized by the accumulation of a small mature B cell lymphoid cells with abundant cytoplasm and “hairy” projections within the peripheral blood smear, bone marrow ...
Mónica Seidi +2 more
doaj +1 more source
Hairy cell leukemia: a histo-cytochemical and ultra-structural study [PDF]
, 1998 We studied five patients with hairy cell leukemia (HCL) diagnosed within the last ten years at the Department of Hematology of Universidade Federal de São Paulo (UNIFESP) - Escola Paulista de Medicina. Our purpose was to analyze the value of transmission
Freymüller-Haapalainen, Edna +3 more
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Leukemia Research Reports, 2019 Fc receptor-like 1 (FCRL1) positively regulates B-cell responses and may involve in the pathogenesis of B-cell malignancies. This study examined the expression pattern of FCRL1 in B-cell non-Hodgkin's lymphoma patients using real-time PCR and flow ...
Zahra Yousefi, Nahid Eskandari
doaj +1 more source
Archives of Pathology & Laboratory Medicine, 2000 AbstractThe morphologic differential diagnosis of mature B-cell neoplasms with cytoplasmic projections includes splenic lymphoma with villous lymphocytes and hairy cell leukemia. Although the classification of hairy cell leukemia is not universally recognized, 3 variants have been described, namely, classic, variant, and Japanese variant, each of which
M L, Wu, H C, Kwaan, C L, Goolsby
openaire +2 more sources
Hairy cell leukemia and pregnancy [PDF]
Терапевтический архив, 2017 The paper presents experience in following up and treating hairy cell leukemia (HCL) during pregnancy. The combination of HCL and pregnancy was observed in 5 patients. The patients’ median age was 35 years (range, 28—42 years).
L S Al-radi +3 more
doaj +1 more source
Hairy cell leukemia with plasmacytoid morphology [PDF]
eJHaemSiba El Hussein, Dennis P. O'Malley
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Case Reports in Oncology, 2018 The BRAF-V600E mutation has been established as a signature alteration occurring almost universally in hairy cell leukemia. Moreover, it can be detected in a small percentage of patients with non-small cell lung cancer.
Maria Mitsogianni +6 more
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BRAF inhibitor and hairy cell leukemia-related transient acantholytic dermatosis [PDF]
, 2020 Grover disease (GD) is an acquired, nonfamilial, nonimmune mediated, transient or persistent acantholytic dermatosis. Herein, we present a 72-year-old man who had clinical and histopathologic findings of GD following two weeks of treatment with ...
Durkin, John R +3 more
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