Results 161 to 170 of about 1,180,341 (309)
Advanced Science, EarlyView.Based on a well‐established in vitro directed differentiation model and an integrated analysis of high‐density cell lineage trees (CLTs) and single‐cell transcriptomes, it is demonstrated that many subclones are formed by sub‐CLTs resembling each other in terms of both cell type compositions and topological structures.
Xiaoyu Zhang +14 more
wiley +1 more source
Applied Sciences, 2019 The volume and complexity of commercial bioreactors for sterile hydroponics and hairy roots are too large for comparative analysis of many cultures. Here a small-scale bioreactor fabricated from standard glass materials and suitable for both airlift and ...
Zana Jamal Kareem +6 more
doaj +1 more source
International Journal of Molecular Sciences, 2018 Linum flavum hairy root lines were established from hypocotyl pieces using Agrobacterium rhizogenes strains LBA 9402 and ATCC 15834. Both strains were effective for transformation but induction of hairy root phenotype was more stable with strain ATCC ...
S. Renouard +15 more
semanticscholar +1 more source
Advanced Science, EarlyView.In this study, saponin‐coated silica@gold nanocarriers responsive to NIR radiation is developed to enhance intratympanic drug delivery for cisplatin‐induced hearing loss (CIHL) treatment. The biocompatibility and oto‐protective properties are validated both in vitro and in vivo.
Rawand A. Mustafa +6 more
wiley +1 more source
Journal of Medicinal Plants, 2013 Background: Silymarin, extracted from the seeds of milk thistle (Silybum marianum (L.) Gaertn) is mostly used for liver disease treatment. Hairy root cultures derived from S. marianum are able to produce silymarin.
T Hasanloo +3 more
doaj
Alkaloid production by a Cinchona officinalis 'Ledgeriana' hairy root culture containing constitutive expression constructs of tryptophan decarboxylase and strictosidine synthase cDNAs from Catharanthus roseus [PDF]
, 1999 Arjan Geerlings +5 more
openalex +1 more source
Advanced Science, EarlyView.A type of polydopamine (PDA) nanogel decorated adhesive and responsive hierarchical microcarriers for ALA delivery and deafness prevention. PDA@microcarriers can protect the encapsulated drugs from external disturbances and prolong their retention time in the inner ear.
Hong Chen +8 more
wiley +1 more source
Advanced Science, EarlyView.D‐galactose (D‐gal) induced inner ear hair cell senescence by inhibiting TFEB transcription. RONIN/HCF1 promotes TFEB transcription to prevent cochlear HCs from D‐gal‐induced senescence through autophagy activation. Abstract Age‐related hearing loss is characterized by senescent inner ear hair cells (HCs) and reduced autophagy.
Yongjie Wei +18 more
wiley +1 more source
Proteome Data Analysis of Hairy Root of Panax ginseng : Use of Expressed Sequence Tag Data of Ginseng for the Protein Identification [PDF]
, 2002 Kyung‐Hoon Kwon +10 more
openalex +1 more source
Advanced Science, EarlyView.The fusion peptide LR27‐modified thermosensitive nanodelivery system exhibits both hair cell targeting and inner ear penetrating properties. This system sustainably and effectively delivers PTH1‐34 to the inner ear of a hearing loss mouse model via the synergistic effects of multiple peptides, achieving satisfactory hearing protection through ...
Jiawen Li +12 more
wiley +1 more source