Results 191 to 200 of about 16,684 (344)

Optimization of Hairy Root Transformation and Application of RUBY as a Reporter in Lotus corniculatus [PDF]

Kaidi Lyu, Xingli Zhang, Wenjie Yu, Shanhua Lyu, Yinglun Fan   +4 more
openalex   +1 more source

Single‐Cell Dissection of Tumor‐Infiltrating Lymphocytes Reveals Cellular Architecture Predictive of Therapeutic Efficacy in Acral Melanoma

Advanced Science, EarlyView.
Autologous tumor‐infiltrating lymphocyte (TIL) therapy shows promising efficacy in acral melanoma, yet determinants of durable response remain unclear. By integrating single‐cell transcriptomics and TCR sequencing, this study reveals that TIL products enriched for T follicular helper and intermediate exhausted T cells establish persistent clonal ...
Chao Zhang, Wanyi Xiao, Hongru Shen, Fenge Li, Ting Li, Weihong Zhang, Haotian Liu, Ziwei Gao, Hongyu Wang, Xiubao Ren, Kexin Chen, Xiangchun Li, Jilong Yang   +12 more
wiley   +1 more source

Engineering Gypsophila elegans hairy root cultures to produce endosomal escape-enhancing saponins. [PDF]

Plant Biotechnol J
Lacchini E, Qu T, Moses T, Volkov AN, Goossens A.   +4 more
europepmc   +1 more source

Approaching Scarless Wound Healing: From Passive Anti‐Fibrotic to Proactive and Programmable Pro‐Regenerative Strategies

Advanced Science, EarlyView.
This review outlines the wound healing process and factors influencing scar formation, explores how certain animals and human fetuses achieve scarless skin or tissue regeneration, and details tissue engineering material strategies employed in scarless wound dressings.
Meimei Fu, Zhuoyi Huang, Jintao Li, Yue Li, Zhou Fang, Yiwen Jiang, Keke Wu, Jinshan Guo   +7 more
wiley   +1 more source

Mother transformer: A High-Throughput, Cost-Effective in Planta Hairy Root Transformation Method for Cannabis. [PDF]

BMC Biotechnol
Ajdanian L, Torkamaneh D.
europepmc   +1 more source

Enhanced Production of Nitrogenated Metabolites with Anticancer Potential in Aristolochia manshuriensis Hairy Root Cultures. [PDF]

Int J Mol Sci, 2023
Shkryl YN, Tchernoded GK, Yugay YA, Grigorchuk VP, Sorokina MR, Gorpenchenko TY, Kudinova OD, Degtyarenko AI, Onishchenko MS, Shved NA, Kumeiko VV, Bulgakov VP.   +11 more
europepmc   +1 more source

Compensatory Interplay Between Clarin‐1 and Clarin‐2 Deafness‐Associated Proteins Governs Phenotypic Variability in Hearing

Advanced Science, EarlyView.
Functional compensation between clarin‐1 and clarin‐2 in cochlear hair cells. Hearing loss associated with CLRN1 mutations shows striking phenotypic variability; however, the underlying mechanisms remain poorly understood. This study reveals that clarin‐1 and clarin‐2 function cooperatively in cochlear hair cells to sustain mechanoelectrical ...
Maureen Wentling, Aïda Yakhlef Sanchez, Nicolas Thelen, Müge Senarisoy, Maria Hogg, Steven Condamine, Andrea Lelli, Emilia Wysocka, Pranav Patni, Sandrine Vitry, Kerem Yasin Yildizhan, Sébastien Le Gal, Sylvie Nouaille, Michael R. Bowl, Marc Thiry, Didier Dulon, Sedigheh Delmaghani, Aziz El‐Amraoui   +17 more
wiley   +1 more source

Establishment of Transient Transformation Systems in Welsh Onion (<i>Allium fistulosum</i> L.): Hairy Root Induction and Protoplast Transformation. [PDF]

Plants (Basel)
Wang D, Liu Y, Zhang Y, Huang X, Wang J, Wang Y, Liu Y, Yan C, Lv B, Jia Y.   +9 more
europepmc   +1 more source

A Mitochondria‐Specific Nanomedicine for Synergistic Chemo‐Photothermal Therapy and Immunogenic Activation Against Breast Cancer

Advanced Science, EarlyView.
Peptide dendrimer–based nanoplatform with mitochondria‐targeting capability was developed for synergistic chemo‐photothermal therapy. The system promotes efficient transcytosis, induces mitochondrial dysfunction, triggers immunogenic cell death (ICD), and enhance antitumor immunity by promoting dendritic cell maturation and T‐cell activation, resulting
Min Li, Jiangqi Feng, Junyang Zhuang, Qingguo Zhong, Yanda Li, Yanzhuo Lv, Shaoteng Huang, Xiangyu Huang, Mingbo Zhang, Xiaofeng Cai, Yuxin Wang, Wenping Chen, Zhenyu Duan, Zhou Chen, Kui Luo, Ning Li   +15 more
wiley   +1 more source

Establishment of an Efficient <i>Agrobacterium rhizogenes</i>-Mediated Hairy Root Transformation System for Functional Analysis in Passion Fruit. [PDF]

Plants (Basel)
Pan J, Zheng Y, Wang T, Xiong P, Cui K, Zeng L, Fang T.   +6 more
europepmc   +1 more source