Results 201 to 210 of about 1,132,099 (329)

Alternative Models for Anticancer Drug Discovery From Natural Products Using Binary Tumor‐Microenvironment‐on‐a‐Chip

open access: yesAdvanced Science, EarlyView.
This study presents a binary tumor‐microenvironment‐on‐a‐chip (T‐MOC) system incorporating multicellular tumor spheroids (MCTs) as an alternative preclinical platform to evaluate the efficacy of anticancer natural products. The T‐MOC model reproduces in vivo drug delivery barriers and physiological conditions, enabling morphological analysis to predict
Youngwon Kim   +7 more
wiley   +1 more source

Hyperspectral Imaging Techniques for Lyophilization: Advances in Data‐Driven Modeling Strategies and Applications

open access: yesAdvanced Science, EarlyView.
Lyophilization is a key process used in the production of biotherapeutic products. This article reviews and discusses the application of HSI on lyophilization, and the strategies that use the resulting data to build models. It is intended to provide guidance and insights for non‐specialist researchers and engineers into leveraging HSI and the data ...
Huiwen Yu   +5 more
wiley   +1 more source

The effects of LED Spectra on synthesis of antiparasitic bioactive compound in Eurycoma longifolia hairy root culture against Blastocystis Sp. [PDF]

open access: yesSci Rep
Abushattal MAK   +7 more
europepmc   +1 more source

Rationally Designed TadA‐Derived Cytosine Editors Enable Context‐Independent Zebrafish Genome Editing

open access: yesAdvanced Science, EarlyView.
A next‐generation cytosine base editor (zTadCBE) and other variants are developed by combining the high‐efficiency (TadCBEa) and low‐indel (TadCBEMax) architectures, followed by the introduction of zebrafish‐optimized mutations (V82S, Q154R) in the TadA domain.
Wei Qin   +7 more
wiley   +1 more source

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