Results 91 to 100 of about 19,894 (182)
Abstract The humanitarian sector has been challenging power relationships between international and local actors for decades, attempting to move towards a mode of operation where local knowledge and capacity are central. The sector is thus striving to promote a more inclusive approach to aid delivery through localisation.
Valerie de Koeijer, Bilge Sahin
wiley +1 more source
The CaM1‐CBP60b‐MYB77 Transcriptional Cascade Regulates K+ Homeostasis and Salt Tolerance in Barley
ABSTRACT Soil salinity is a major abiotic stress that threatens global crop productivity. Calcium (Ca2+) is a pivotal second messenger in plant stress signalling, but how Ca2+ sensors such as calmodulin (CaM) transcriptionally control ion homeostasis and salt tolerance remains largely understood in crops.
Yunfeng Xu +18 more
wiley +1 more source
Synthese Unkonventioneller α‐Polyhalogenierter Amine Durch Hydroaminoalkylierung
Es wird ein redox‐neutrales Verfahren beschrieben, bei dem Alkene und Alkine unter Verwendung stabiler Hemiaminal‐Reagenzien in α‐Polyhalogenmethylamine umgewandelt werden. Dieser Ansatz ermöglicht den Zugang zu α‐CF3‐, α‐CF2H‐, α‐CF2Cl‐, und α‐CFClH‐Aminen und besticht durch ein breites Substratspektrum, eine hohe Toleranz gegenüber funktionellen ...
Angela K. Hofmeister +9 more
wiley +1 more source
Unified Synthesis of Unconventional α‐Polyhalogenated Amines Through Hydroaminoalkylation
A unified, redox‐neutral method that transforms alkenes and alkynes into α‐polyhalomethyl amines using stable hemiaminal reagents is reported. This approach enables access to CF3, CF2H, CF2Cl, and CFClH motifs, expanding halogenated amine space with broad substrate scope, functional group tolerance, and applicability to late‐stage modification of drug ...
Angela K. Hofmeister +9 more
wiley +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
A swelling‐programmed micropatterned hydrogel guides adherent cells through a controlled transition from cell–matrix anchoring to cadherin‐mediated cell–cell compaction, enabling rapid assembly of high‐viability spheroids with defined size and morphology.
Han Gyeol Nam +8 more
wiley +1 more source
Cholesterol‐enriched plasma membranes in hepatocellular carcinoma impede drug penetration. Cholesterol (+)‐liposomes act as membrane‐specific detergents, extracting cholesterol and reducing barrier function without cytotoxicity. Following endocytosis, cholesterol transfers from endosomes to liposomes and is metabolized in the ER.
Chansik Kim +9 more
wiley +1 more source
A supramolecular chirality evolution strategy in chiral low‐bandgap fused‐ring conjugated molecules enables high‐performance near‐infrared (NIR) circularly polarized light photodetection. Halogen substitution and thermal annealing induce chiral amplification and hierarchical ordering. Integrated into Schottky barrier vertical transistors, the optimized
Jaeyong Ahn +6 more
wiley +1 more source
Abstract We describe a surgical technique repairing medium‐to‐large anterosuperior rotator cuff (RC) tear that combines long head of the biceps tendon (LHBT) augmentation with a dermal allograft patch using a knotless double‐row repair. LHBT augmentation is done using a triple‐loaded anchor placed 5 mm posterior to the bicipital groove at the bone ...
Gabriel Antonio A. Escueta +5 more
wiley +1 more source
Ethnic Differences in Unmet Care Needs Among Cancer Survivors in Utah Using a Mixed Methods Approach
ABSTRACT Background Cancer survivors' unmet care needs can negatively affect well‐being and quality of life, yet few studies focus on how Hispanic/Latino (Hispanic) survivors' needs may differ from those of non‐Hispanic White (NHW) survivors. Aims To explore unmet needs of cancer survivors by ethnicity.
Sara G. Jackson +9 more
wiley +1 more source

